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题名: Repair of dGMP hydroxyl radical adducts by verbascoside via electron transfer: A pulse radiolysis study
作者: Li, WY; Zheng, RL(郑荣梁); Su, BN; Jia, ZJ(贾忠建); Li, HC; Jiang, Y; Yao, S; Lin, NY
收录类别: SCIE ; PubMed ; MEDLINE ; BIOSIS
出版日期: 1996-04
刊名: International Journal of Radiation Biology
卷号: 69, 期号:4, 页码:481-485
出版者: INFORMA HEALTHCARE
出版地: LONDON
英文摘要: The repair activity of verbascoside (VER), isolated from Pedicularis spicata, towards the oxidizing hydroxyl radical adduct of dGMP and its reaction mechanism were studied using pulse radiolysis. Upon pulse radiolysis of nitrous oxide saturated aqueous solution of 2'-deoxyguanosine-5'-monophosphate (dGMP) and VER, it was found that the transient absorption spectrum of the hydroxyl adduct of dGMP decays with the formation of that of the phenoxyl radical of VER, several tens of microseconds after the electron pulse. From the formation kinetics of the phenoxyl radical of VER, the rate constant of the repair reaction was determined to be 1.12 x 10(9) dm(3) mol(-1) s(-1).
作者部门: LANZHOU UNIV, DEPT BIOL, LANZHOU 730000, PEOPLES R CHINA ; LANZHOU UNIV, INST ORGAN CHEM, LANZHOU 730000, PEOPLES R CHINA ; ACAD SINICA, SHANGHAI INST NUCL RES, LAB RADIAT CHEM, SHANGHAI 201800, PEOPLES R CHINA
学科分类: Life Sciences & Biomedicine - Other Topics; Nuclear Science & Technology; Radiology, Nuclear Medicine & Medical Imaging
文章类型: Article
语种: 英语
DOI: 10.1080/095530096145779
ISSN号: 0955-3002
WOS记录号: WOS:A1996UK06300008
PM记录号: 8627130
BIOSIS记录号: BCI:BCI199699062451
IR记录号: BCI:BCI199699062451
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内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/115998
Appears in Collections:生命科学学院_期刊论文

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Recommended Citation:
Li, WY,Zheng, RL,Su, BN,et al. Repair of dGMP hydroxyl radical adducts by verbascoside via electron transfer: A pulse radiolysis study[J]. International Journal of Radiation Biology,1996,69(4):481-485.
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