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Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance 期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 108, 页码: 364-372
Authors:  Wang, ZL;  Li, N;  Wang, P;  Tang, HH;  Han, ZL;  Song, JJ;  Li, XH;  Yu, HP;  Zhang, T;  Zhang, R...Wang, ZL;  Li, N;  Wang, P;  Tang, HH;  Han, ZL;  Song, JJ;  Li, XH;  Yu, HP;  Zhang, T;  Zhang, R;  Xu, B;  Zhang, MN;  Fang, Q(方泉);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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Chimeric peptide  Endomorphin-2  Neuropeptide FF  Opioid  Antinociception  Non-tolerance  
Proteomic analysis of apoptosis induction by lariciresinol in human HepG2 cells 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2016, 卷号: 256, 页码: 209-219
Authors:  Ma, ZJ;  Wang, XX;  Su, G;  Yang, JJ;  Zhu, YJ;  Wu, YW;  Li, J;  Lu, L;  Zeng, L;  Pei, HX...Ma, ZJ;  Wang, XX;  Su, G;  Yang, JJ;  Zhu, YJ;  Wu, YW;  Li, J;  Lu, L;  Zeng, L;  Pei, HX;  Wang, XX (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Med, 205 Tianshui Rd South, Lanzhou 730000, Gansu, Peoples R China.
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Lariciresinol  HepG2 cells  Apoptosis  Proteomics  Bioinformatics  
Asymmetric Synthesis of CF3- and Indole-Containing Thiochromanes via a Squaramide-Catalyzed Michael-Aldol Reaction 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 15, 页码: 3546-3549
Authors:  Zhu, YY;  Dong, ZH;  Cheng, X;  Zhong, XL;  Liu, XL;  Lin, L;  Shen, ZQ;  Yang, PJ;  Li, Y;  Wang, HL...Zhu, YY;  Dong, ZH;  Cheng, X;  Zhong, XL;  Liu, XL;  Lin, L;  Shen, ZQ;  Yang, PJ;  Li, Y;  Wang, HL;  Yan, WJ;  Wang, KR;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Inst Pharmacol, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic,Med Sci, Lanzhou 730000, Peoples R China.;  Wang, R (reprint author), Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China.
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Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex 期刊论文
BRAIN STRUCTURE & FUNCTION, 2016, 卷号: 221, 期号: 6, 页码: 3327-3336
Authors:  Shao, YF(邵玉峰);  Wang, C;  Xie, JF;  Kong, XP;  Xin, L;  Dong, CY;  Li, J;  Ren, WT;  Hou, YP;  Hou, YP (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Dept Neurosci, 199 Donggang Xi Rd, Lanzhou 730000, Peoples R China....Shao, YF(邵玉峰);  Wang, C;  Xie, JF;  Kong, XP;  Xin, L;  Dong, CY;  Li, J;  Ren, WT;  Hou, YP;  Hou, YP (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Dept Neurosci, 199 Donggang Xi Rd, Lanzhou 730000, Peoples R China.;  Hou, YP (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Dept Anat, 199 Donggang Xi Rd, Lanzhou 730000, Peoples R China.;  Hou, YP (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Dept Histol, 199 Donggang Xi Rd, Lanzhou 730000, Peoples R China.;  Hou, YP (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Dept Embryol, 199 Donggang Xi Rd, Lanzhou 730000, Peoples R China.
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Neuropeptide S (NPS)  Neuropeptide S receptor (NPSR)  Olfactory spatial memory  Subiculum complex  Muscarinic cholinergic receptor  N-methyl-D-aspartate receptor  Antagonist  c-Fos  
A flavonoid compound from Chrysosplenium nudicaule inhibits growth and induces apoptosis of the human stomach cancer cell line SGC-7901 期刊论文
PHARMACEUTICAL BIOLOGY, 2016, 卷号: 54, 期号: 7, 页码: 1133-1139
Authors:  Luo, YP(雒艳萍);  Yu, HJ;  Yang, YS;  Tian, WH;  Dong, KZ;  Shan, JY;  Ma, XM;  Ma, XM (reprint author), Lanzhou Univ, Sch Basic Med Sci, Dept Immunol, Lanzhou 730000, Peoples R China.
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Antitumor  cell-cycle arrest  Tibetan medicine  
Silver-Catalyzed Difluoroamidation of Activated Alkenes for the Construction of Difluorinated 3,3-Disubstituted Oxindoles 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2016, 卷号: 81, 期号: 13, 页码: 5782-5788
Authors:  Wang, C;  Chen, Q;  Guo, QP;  Liu, H;  Xu, ZQ;  Liu, YB;  Wang, MR;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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BN-9, a chimeric peptide with mixed opioid and neuropeptide FF receptor agonistic properties, produces nontolerance-forming antinociception in mice 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2016, 卷号: 173, 期号: 11, 页码: 1864-1880
Authors:  Li, N;  Han, ZL;  Wang, ZL;  Xing, YH;  Sun, YL;  Li, XH;  Song, JJ;  Zhang, T;  Zhang, R;  Zhang, MN...Li, N;  Han, ZL;  Wang, ZL;  Xing, YH;  Sun, YL;  Li, XH;  Song, JJ;  Zhang, T;  Zhang, R;  Zhang, MN;  Xu, BA;  Fang, Q(方泉);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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Adherence to ARRIVE Guidelines in Chinese Journal Reports on Neoplasms in Animals 期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 5
Authors:  Liu, YL;  Zhao, XX;  Mai, YF;  Li, XX;  Wang, J;  Chen, LL;  Mu, J;  Jin, GX;  Gou, HP;  Sun, WT...Liu, YL;  Zhao, XX;  Mai, YF;  Li, XX;  Wang, J;  Chen, LL;  Mu, J;  Jin, GX;  Gou, HP;  Sun, WT;  Feng, YC;  Liu, YL (reprint author), Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, Lanzhou 730000, Peoples R China.;  Liu, YL (reprint author), Key Lab Evidence Based Med & Knowledge Translat G, Lanzhou, Peoples R China.;  Liu, YL (reprint author), China Acad Chinese Med Sci, Inst Basic Res Clin Med, Beijing, Peoples R China.
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Proteomic identification of predictive tissue biomarkers of sensitive to neoadjuvant chemotherapy in squamous cervical cancer 期刊论文
LIFE SCIENCES, 2016, 卷号: 151, 页码: 102-108
Authors:  Guo, L;  Zhang, CX;  Zhu, JH;  Yang, YQ;  Lan, JF;  Su, G;  Xie, XD;  Xie, XD (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.
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Squamous cervical cancer  Neoadjuvant chemotherapy  Proteomics  Drug sensitivity  
A Highly Conserved Salt Bridge Stabilizes the Kinked Conformation of 2,3-Sheet Essential for Channel Function of P2X4 Receptors 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 15, 页码: 7990-8003
Authors:  Zhao, WS;  Sun, MY;  Sun, LF;  Liu, Y;  Yang, Y;  Huang, LD;  Fan, YZ;  Cheng, XY;  Cao, P;  Hu, YM...Zhao, WS;  Sun, MY;  Sun, LF;  Liu, Y;  Yang, Y;  Huang, LD;  Fan, YZ;  Cheng, XY;  Cao, P;  Hu, YM;  Li, LY;  Tian, Y;  Wang, R(王锐);  Yu, Y;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Life Sci, Lanzhou 730000, Peoples R China.;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.;  Yu, Y (reprint author), Shanghai Jiao Tong Univ, Sch Med, Inst Med Sci, Shanghai 200025, Peoples R China.;  Yu, Y (reprint author), Shanghai Jiao Tong Univ, Sch Med, Dept Pharmacol & Chem Biol, Shanghai 200025, Peoples R China.;  Yu, Y (reprint author), Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Hunan, Peoples R China.
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ATP  conformational change  ion channel  protein expression  protein stability  P2X receptors  salt bridge