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Spermidine ameliorates the neuronal aging by improving the mitochondrial function in vitro 期刊论文
EXPERIMENTAL GERONTOLOGY, 2018, 卷号: 108, 页码: 77-86
Authors:  Jing, YH;  Yan, JL;  Wang, QJ;  Chen, HC;  Ma, XZ;  Yin, J;  Gao, LP;  Gao, LP (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Biochem & Mol Biol, 199 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.
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Mitochondria  Spermidine  Nerve cells  Aging  
Catalyst-free tandem halogenation/semipinacol rearrangement of allyl alcohols with sodium halide in water 期刊论文
GREEN CHEMISTRY, 2018, 卷号: 20, 页码: 2477-2480
Authors:  Zeng, ZX;  Xun, XD;  Huang, LW;  Xu, JC;  Zhu, GM;  Li, GF;  Sun, WS;  Hong, L;  Wang, R;  Hong, L (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China....Zeng, ZX;  Xun, XD;  Huang, LW;  Xu, JC;  Zhu, GM;  Li, GF;  Sun, WS;  Hong, L;  Wang, R;  Hong, L (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China.;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.
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Regio- and stereospecific Friedel-Crafts alkylation of indoles with spiro-epoxyoxindoles 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 19, 页码: 3655-3661
Authors:  Li, GF;  Bao, GJ;  Zhu, GM;  Li, YP;  Huang, LW;  Sun, WS;  Hong, L;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.;  Hong, L (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China....Li, GF;  Bao, GJ;  Zhu, GM;  Li, YP;  Huang, LW;  Sun, WS;  Hong, L;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.;  Hong, L (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China.
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Druggable negative allosteric site of P2X3 receptors 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 19, 页码: 4939-4944
Authors:  Wang, J;  Wang, Y;  Cui, WW;  Huang, YC;  Yang, Y;  Liu, Y;  Zhao, WS;  Cheng, XY;  Sun, WS;  Cao, P...Wang, J;  Wang, Y;  Cui, WW;  Huang, YC;  Yang, Y;  Liu, Y;  Zhao, WS;  Cheng, XY;  Sun, WS;  Cao, P;  Zhu, MX;  Wang, R;  Hattori, M;  Yu, Y;  Hattori, M (reprint author), Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Sch Life Sci, Dept Physiol & Biophys,State Key Lab Genet Engn, Shanghai 200438, Peoples R China.;  Yu, Y (reprint author), Shanghai Jiao Tong Univ, Sch Med, Inst Med Sci, Dept Pharmacol & Chem Biol, Shanghai 200025, Peoples R China.;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.;  Yu, Y (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200025, Peoples R China.
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P2X3 receptors  allosteric inhibition  X-ray crystallography  AF-219  AF-353  
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 页码: 988-1002
Authors:  Liu, K;  Fang, LJ;  Sun, HY;  Pan, ZY;  Zhang, JC;  Chen, JT;  Shao, XM;  Wang, W;  Tan, YY;  Ding, ZH...Liu, K;  Fang, LJ;  Sun, HY;  Pan, ZY;  Zhang, JC;  Chen, JT;  Shao, XM;  Wang, W;  Tan, YY;  Ding, ZH;  Ao, LJ;  Wu, CL;  Liu, XQ;  Li, HS;  Wang, R;  Su, W;  Li, HC;  Li, HC (reprint author), Shenzhen Inst Adv Technol, 1068 Xueyuan Blvd, Shenzhen 518055, Guangdong, Peoples R China.;  Su, W (reprint author), Lanzhou Univ, 199 West Donggang Rd, Lanzhou 730020, Gansu, Peoples R China.
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Anti-atherosclerotic effect of Fermentum Rubrum and Gynostemma pentaphyllum mixture in high-fat emulsion- and vitamin D-3-induced atherosclerotic rats 期刊论文
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, 2018, 卷号: 81, 页码: 398-408
Authors:  Gou, SH;  Liu, BJ;  Han, XF;  Wang, L;  Zhong, C;  Liang, S;  Liu, H;  Qiang, Y;  Zhang, Y;  Ni, JM...Gou, SH;  Liu, BJ;  Han, XF;  Wang, L;  Zhong, C;  Liang, S;  Liu, H;  Qiang, Y;  Zhang, Y;  Ni, JM;  Ni, JM (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Gansu, Peoples R China.
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Atherosclerosis  Fermentum Rubrum  Gynostemma pentaphyllum  Gypenosides  Hyperlipidemia  Red yeast rice  
Seneca Valley Virus 3C(pro) abrogates the IRF3-and IRF7-mediated innate immune response by degrading IRF3 and IRF7 期刊论文
VIROLOGY, 2018, 卷号: 518, 期号: 19, 页码: 1-7
Authors:  Xue, Q;  Liu, HS;  Zhu, ZX;  Yang, F;  Ma, LN;  Cai, XP;  Xue, QH;  Zheng, HX;  Zheng, HX (reprint author), Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol,Minist Agr, Natl Foot & Mouth Dis Reference Lab,Key Lab Anim, Lanzhou 730046, Gansu, Peoples R China.
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Seneca Valley Virus  Innate immunity  3C-like protease  IRF3  IRF7  
Prolonged intervals during Mycobacterium tuberculosis subunit vaccine boosting contributes to eliciting immunity mediated by central memory-like T cells 期刊论文
TUBERCULOSIS, 2018, 卷号: 110, 期号: 5-6, 页码: 104-111
Authors:  Bai, CX;  He, JJ;  Niu, HX;  Hu, LN;  Luo, YP;  Liu, X;  Peng, L;  Zhu, BD;  Zhu, BD (reprint author), Lanzhou Univ, Inst Pathogen Biol, Sch Basic Med Sci, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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Mycobacterium tuberculosis  Subunit vaccine  Immunization schedules  Immune memory  Protective efficacy  
Phosphoric Acid Catalyzed Asymmetric [2+2] Cyclization/Penicillin-Penillonic Acid Rearrangement 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 19, 页码: 4921-4925
Authors:  Zhang, M;  Yu, CJ;  Xie, JQ;  Xun, XD;  Sun, WS;  Hong, L;  Wang, R;  Hong, L (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China.;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.
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asymmetric cyclization  azlactones  carbolines  chiral phosphoric acids  PPA rearrangement  
Visible-Light-Promoted Dearomative Fluoroalkylation of beta-Naphthols through Intermolecular Charge Transfer 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 页码: 4747-4751
Authors:  Guo, QP;  Wang, MR;  Liu, H;  Wang, R;  Xu, ZQ;  Xu, ZQ (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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beta-naphthols  dearomatization  donor-acceptor complexes  fluoroalkylation  intermolecular charge transfer