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题名: Quality Control of Fingerprint of Radix Astragali by High-Performance Liquid Chromatography Coupled with Chemometric Methods
作者: Feng, ZF; Sun, XM; Ning, SR; Di, DL
收录类别: SCIE
出版日期: 2012-09
刊名: CURRENT PHARMACEUTICAL ANALYSIS
卷号: 8, 期号:3, 页码:225-235
出版者: BENTHAM SCIENCE PUBL LTD
出版地: SHARJAH
英文摘要: High-performance liquid chromatography (HPLC) was employed in a fingerprint analysis of Radix astragali. A characteristic HPLC profile of known Radix astragali samples collected from five primary habitats in China was established by evaluating 15 samples with chemometric methods, including similarity evaluation, hierarchical cluster analysis (HCA), principal component analysis (PCA) and discriminant analysis (DA). The feasibility and advantages of employing chromatographic fingerprinting combined with chemometric methods were investigated and demonstrated in the evaluation of Radix astragali for the first time. The results showed that the chromatographic fingerprint combined with chemometric methods could efficiently distinguish Radix astragali from various areas and provide quality control in the quantitative analysis.
关键词: Chemometric ; Fingerprint ; HPLC ; Radix astragali
作者部门: [Feng, Zu-fei ; Sun, Xiao-ming ; Di, Duo-long] Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem NW Plant Resources, Lanzhou 730000, Peoples R China ; [Feng, Zu-fei ; Sun, Xiao-ming ; Di, Duo-long] Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China ; [Feng, Zu-fei ; Sun, Xiao-ming] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China ; [Ning, Sheng-rong ; Di, Duo-long] Lanzhou Univ, Pharmacol Sch, Lanzhou 730000, Peoples R China
通讯作者: Di, DL (reprint author), Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem NW Plant Resources, 18 Tianshui Middle Rd, Lanzhou 730000, Peoples R China.
学科分类: Pharmacology & Pharmacy
文章类型: Review
所属项目编号: National Science and Technology Support Programme [2007BAI37B05] ; Chinese Academy of Sciences (CAS)
所属项目名称: 国家科技支撑计划
项目资助者: MOST
语种: 英语
ISSN号: 1573-4129
WOS记录号: WOS:000307962800002
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内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/121930
Appears in Collections:药学院_期刊论文

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Recommended Citation:
Feng, ZF,Sun, XM,Ning, SR,et al. Quality Control of Fingerprint of Radix Astragali by High-Performance Liquid Chromatography Coupled with Chemometric Methods[J]. CURRENT PHARMACEUTICAL ANALYSIS,2012,8(3):225-235.
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