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题名: The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film
作者: Liu, YJ; Luo, J; Liu, B(刘斌); Zhang, JY
收录类别: SCIE ; EI
出版日期: 2011-05-15
刊名: APPLIED SURFACE SCIENCE
卷号: 257, 期号:15, 页码:6429-6434
英文摘要: The objective of the present study is to preliminarily explore the effect of surface chemistry modification of Ti6Al4V with a fluorine-contained copolymer thin film on the cellular behavior of osteoblasts. A fluorine-contained random copolymer thin film was fabricated on Ti6Al4V substrate, and then characterized by X-ray photoelectron spectroscopy (XPS), contact angle meter and surface profiler. The results showed that the surface modification of Ti6Al4V alloy could simultaneously transform the surface chemical constitution and reduce the surface energy evidently. However, the surface morphology and roughness of the Ti6Al4V substrate were hardly changed after the modification. By immersion process with simulated body fluid (SBF) and then by in vitro cytotoxicity test with MC3T3-E1 osteoblasts, the fluorine-contained copolymer thin film exhibited desirable stability and admirable cytocompatibility. In conclusion, the fluorine-contained copolymer thin film could be easily applied in modifying various solid surfaces, and the as-fabricated film also has potential applications in biomedical field. (C) 2011 Elsevier B.V. All rights reserved.
关键词: Copolymer ; Thin film ; Ti6Al4V ; Cytocompatibility ; Osteoblast
作者部门: [Liu, Yijun ; Liu, Bin] Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China ; [Liu, Yijun ; Luo, Jia ; Zhang, Junyan] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China ; [Luo, Jia] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
通讯作者: Liu, B (reprint author), Lanzhou Univ, Sch Stomatol, 199 Donggang W Rd, Lanzhou 730000, Peoples R China.
学科分类: Chemistry ; Materials Science ; Physics
文章类型: Article
所属项目编号: National Natural Science Foundation of China [50823008, 20673131] ; Chinese Academy of Sciences
所属项目名称: 国家自然科学基金项目
项目资助者: NSFC
语种: 英语
DOI: 10.1016/j.apsusc.2011.02.021
ISSN号: 0169-4332
WOS记录号: WOS:000289512500019
EI记录号: 20111613920229
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/122086
Appears in Collections:口腔医学院_期刊论文

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Recommended Citation:
Liu, YJ,Luo, J,Liu, B,et al. The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film[J]. APPLIED SURFACE SCIENCE,2011,257(15):6429-6434.
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