兰州大学机构库 >口腔医学院
The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film
Liu, YJ; Luo, J; Liu, B(刘斌); Zhang, JY; Liu, B (reprint author), Lanzhou Univ, Sch Stomatol, 199 Donggang W Rd, Lanzhou 730000, Peoples R China.
收录类别SCIE ; EI
2011-05-15
发表期刊APPLIED SURFACE SCIENCE
卷号257期号:15页码:6429-6434
出版者ELSEVIER
出版地AMSTERDAM
摘要The objective of the present study is to preliminarily explore the effect of surface chemistry modification of Ti6Al4V with a fluorine-contained copolymer thin film on the cellular behavior of osteoblasts. A fluorine-contained random copolymer thin film was fabricated on Ti6Al4V substrate, and then characterized by X-ray photoelectron spectroscopy (XPS), contact angle meter and surface profiler. The results showed that the surface modification of Ti6Al4V alloy could simultaneously transform the surface chemical constitution and reduce the surface energy evidently. However, the surface morphology and roughness of the Ti6Al4V substrate were hardly changed after the modification. By immersion process with simulated body fluid (SBF) and then by in vitro cytotoxicity test with MC3T3-E1 osteoblasts, the fluorine-contained copolymer thin film exhibited desirable stability and admirable cytocompatibility. In conclusion, the fluorine-contained copolymer thin film could be easily applied in modifying various solid surfaces, and the as-fabricated film also has potential applications in biomedical field. (C) 2011 Elsevier B.V. All rights reserved.
关键词Copolymer Thin film Ti6Al4V Cytocompatibility Osteoblast
作者部门[Liu, Yijun;
Liu, Bin] Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China;
[Liu, Yijun;
Luo, Jia;
Zhang, Junyan] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China;
[Luo, Jia] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
学科领域Chemistry ; Materials Science ; Physics
所属项目编号National Natural Science Foundation of China [50823008, 20673131] ; Chinese Academy of Sciences
资助项目国家自然科学基金项目
项目资助者NSFC
DOI10.1016/j.apsusc.2011.02.021
ISSN0169-4332
文章类型Article
语种英语
WOS记录号WOS:000289512500019
EI记录号20111613920229
第一机构
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文献类型期刊论文
条目标识符http://ir.lzu.edu.cn/handle/262010/122086
Collection口腔医学院
通讯作者Liu, B (reprint author), Lanzhou Univ, Sch Stomatol, 199 Donggang W Rd, Lanzhou 730000, Peoples R China.
Recommended Citation:
GB/T 7714
Liu, YJ,Luo, J,Liu, B,et al. The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film[J]. APPLIED SURFACE SCIENCE,2011,257(15):6429-6434.
APA Liu, YJ,Luo, J,Liu, B,Zhang, JY,&Liu, B .(2011).The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film.APPLIED SURFACE SCIENCE,257(15),6429-6434.
MLA Liu, YJ,et al."The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film".APPLIED SURFACE SCIENCE 257.15(2011):6429-6434.
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