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题名: The protective effect of apelin on ischemia/reperfusion injury
作者: Yang, YJ; Lu:, SY(吕少瑜); Lyu, SK; Wu, DD; Chen, Q
收录类别: SCIE ; PubMed ; MEDLINE
出版日期: 2015-01
刊名: PEPTIDES
卷号: 63, 页码:43-46
出版者: ELSEVIER
出版地: NEW YORK
英文摘要: Apelin is the endogenous ligand for the APJ, a member of the G protein coupled receptors family. Apelin/APJ system is widely distributed in central nervous system and peripheral tissues, especially in heart, lung and kidney. Apelin plays important physiological and pathological roles in cardiovascular system, immune system, neuroprotection, etc. This article outlines the protective effect of apelin on ischemia/reperfusion (I/R) injury. Apelin could activate multiple protective mechanisms to prevent heart, brain, liver and kidney I/R injury. Apelin/APJ system may be a promising therapeutic target for ischemic and other related diseases. (C) 2014 Elsevier Inc. All rights reserved.
关键词: Apelin ; APJ ; Ischemia/reperfusion injury ; Heart ; Brain
作者部门: [Yang, Yanjie ; Lv, Shuang-Yu ; Wu, Dongdong] Henan Univ, Sch Med, Kaifeng 475004, Henan, Peoples R China ; [Lyu, Shuang-Kun] Lanzhou Univ, Key Lab Nonferrous Met Chem & Resources Utilizat, Coll Chem & Chem Engn, Lanzhou 730000, Gansu, Peoples R China ; [Chen, Qiang] Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Gansu, Peoples R China
通讯作者: Lv, SY (reprint author), Henan Univ, Sch Med, Jinming Ave, Kaifeng 475004, Henan, Peoples R China.
学科分类: Biochemistry & Molecular Biology; Pharmacology & Pharmacy
文章类型: Review
语种: 英语
DOI: 10.1016/j.peptides.2014.11.001
ISSN号: 0196-9781
WOS记录号: WOS:000352153500013
PM记录号: 25447414
IR记录号: WOS:000352153500013
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内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/180007
Appears in Collections:化学化工学院_期刊论文

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Recommended Citation:
Yang, YJ,Lv, SY,Lyu, SK,et al. The protective effect of apelin on ischemia/reperfusion injury[J]. PEPTIDES,2015,63:43-46.
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