兰州大学机构库 >化学化工学院
The protective effect of apelin on ischemia/reperfusion injury
Yang, YJ; Lu:, SY(吕少瑜); Lyu, SK; Wu, DD; Chen, Q; Lv, SY (reprint author), Henan Univ, Sch Med, Jinming Ave, Kaifeng 475004, Henan, Peoples R China.
收录类别SCIE ; PubMed ; MEDLINE
2015-01
发表期刊PEPTIDES
卷号63页码:43-46
出版者ELSEVIER
出版地NEW YORK
摘要Apelin is the endogenous ligand for the APJ, a member of the G protein coupled receptors family. Apelin/APJ system is widely distributed in central nervous system and peripheral tissues, especially in heart, lung and kidney. Apelin plays important physiological and pathological roles in cardiovascular system, immune system, neuroprotection, etc. This article outlines the protective effect of apelin on ischemia/reperfusion (I/R) injury. Apelin could activate multiple protective mechanisms to prevent heart, brain, liver and kidney I/R injury. Apelin/APJ system may be a promising therapeutic target for ischemic and other related diseases. (C) 2014 Elsevier Inc. All rights reserved.
关键词Apelin APJ Ischemia/reperfusion injury Heart Brain
作者部门[Yang, Yanjie;
Lv, Shuang-Yu;
Wu, Dongdong] Henan Univ, Sch Med, Kaifeng 475004, Henan, Peoples R China;
[Lyu, Shuang-Kun] Lanzhou Univ, Key Lab Nonferrous Met Chem & Resources Utilizat, Coll Chem & Chem Engn, Lanzhou 730000, Gansu, Peoples R China;
[Chen, Qiang] Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Gansu, Peoples R China
学科领域Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
DOI10.1016/j.peptides.2014.11.001
ISSN0196-9781
文章类型Review
语种英语
WOS记录号WOS:000352153500013
PM记录号25447414
IR记录号WOS:000352153500013
第一机构
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文献类型期刊论文
条目标识符http://ir.lzu.edu.cn/handle/262010/180007
Collection化学化工学院
通讯作者Lv, SY (reprint author), Henan Univ, Sch Med, Jinming Ave, Kaifeng 475004, Henan, Peoples R China.
Recommended Citation:
GB/T 7714
Yang, YJ,Lv, SY,Lyu, SK,et al. The protective effect of apelin on ischemia/reperfusion injury[J]. PEPTIDES,2015,63:43-46.
APA Yang, YJ,Lv, SY,Lyu, SK,Wu, DD,Chen, Q,&Lv, SY .(2015).The protective effect of apelin on ischemia/reperfusion injury.PEPTIDES,63,43-46.
MLA Yang, YJ,et al."The protective effect of apelin on ischemia/reperfusion injury".PEPTIDES 63(2015):43-46.
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