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题名: BODIPY-derived piperazidine fluorescent near-neutral pH indicator and its bioimaging
作者: Deng, M; Yang, CD; Gong, DY; Iqbal, A; Tang, XL(唐晓亮); Liu, WS(刘伟生); Qin, WW
收录类别: SCIE ; EI
出版日期: 2016-09
刊名: SENSORS AND ACTUATORS B-CHEMICAL
卷号: 232, 页码:492-498
出版者: ELSEVIER
出版地: LAUSANNE
英文摘要: Two new 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) dyes (1 and 2) with piperazine subunits on position 3 or 5 were synthesized. Their absorption and steady-state fluorescence properties were investigated as a function of solvent. In water/MeCN (9:1, V/V) solution, the dyes show fluorescent enhancement upon increasing the acidity of the solution. They can be used in water/MeCN (9:1, V/V) solution as fluorescent pH probes excitable with visible light, with pK(a) values near-neutral (around 6.5 and 6.8). Dyes 1 and 2 are readily taken up by biological cells in the cytosol where it has no obvious toxic effects. (C) 2016 Elsevier B.V. All rights reserved.
关键词: BODIPY ; Piperazine ; Near-neutral pH ; Biological cells
作者部门: [Qin, Wenwu] Lanzhou Univ, Coll Chem & Chem Engn, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China ; Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
通讯作者: Qin, WW (reprint author), Lanzhou Univ, Coll Chem & Chem Engn, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China.
学科分类: Chemistry; Electrochemistry; Instruments & Instrumentation
文章类型: Article
所属项目编号: National Science Foundation for Fostering Talents in Basic Research of the National Natural Science Foundation of China [J1103307]
所属项目名称: 国家基础科学人才培养基金项目
项目资助者: NSFC
语种: 英语
DOI: 10.1016/j.snb.2016.04.003
ISSN号: 0925-4005
WOS记录号: WOS:000375483000063
EI记录号: 20161602244327
IR记录号: WOS:000375483000063
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内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/180558
Appears in Collections:化学化工学院_期刊论文

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Recommended Citation:
Deng, M,Yang, CD,Gong, DY,et al. BODIPY-derived piperazidine fluorescent near-neutral pH indicator and its bioimaging[J]. SENSORS AND ACTUATORS B-CHEMICAL,2016,232:492-498.
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