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兰州大学机构库  > 化学化工学院  > 期刊论文
题名: A dual-color fluorescent biosensing platform based on WS2 nanosheet for detection of Hg2+ and Ag+
其他题名: A dual-color fluorescent biosensing platform based on WS2nanosheet for detection of Hg2+and Ag+
作者: Zuo, XW; Zhang, HG; Zhu, Q; Wang, WF; Feng, J; Chen, XG(陈兴国)
收录类别: SCIE ; EI ; PubMed ; MEDLINE ; BIOSIS
出版日期: 2016-11-15
刊名: BIOSENSORS & BIOELECTRONICS
卷号: 85, 页码:464-470
出版者: ELSEVIER
出版地: OXFORD
英文摘要: In this work, an effective dual-color fluorescent biosensing platform based on WS2 nanosheets was developed for homogeneous detection of Hg2+ and Ag+. This sensing platform was constituted by exploiting the fluorescence quenching ability of WS2 nanosheets and the interactions between WS2 nanosheets and DNA molecules. In the absence of additional any masking agents, the biosensor could achieve detection of Hg2+ and Ag+ in the same solution by monitoring fluorescence intensity changes at 525 nm and 583 nm, respectively. Hg2+ and Ag+ were selectively detected in the concentration range from 6.0-650.0 nM and 5.0-1000.0 nM, respectively, with the detection limit of 3.3 nM and 1.2 nM, respectively. It was also demonstrated that the WS2 nanosheet-based sensing platform was suitable for the simultaneous detection of Hg2+ and Ag+ in drinking water, serum and cell lysate samples. Moreover, the possible mechanism of fluorescence quenching by WS2 nanosheets was revealed to be related to static quenching, dynamic quenching, and Forster resonant energy transfer (FRET). This work extended the application of WS2 nanosheets to environmental monitoring and medical diagnosis. (C) 2016 Elsevier B.V. All rights reserved.
关键词: WS2 nanosheet ; Dual-color fluorescent biosensor ; Hg2+ ; Ag+ ; Homogeneous detection
作者部门: [Zuo, Xianwei ; Zhang, Huige ; Zhu, Qian ; Wang, Weifeng ; Feng, Jie ; Chen, Xingguo] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China ; [Zuo, Xianwei ; Zhang, Huige ; Zhu, Qian ; Wang, Weifeng ; Feng, Jie ; Chen, Xingguo] Lanzhou Univ, Dept Chem, Lanzhou 730000, Peoples R China ; [Chen, Xingguo] Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China ; [Zuo, Xianwei] Key Lab Sensor & Sensor Technol Gansu Prov, Lanzhou 730000, Peoples R China ; [Zuo, Xianwei] Gansu Acad Sci, Inst Sensor Technol, Lanzhou 730000, Peoples R China
通讯作者: Chen, XG (reprint author), Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
学科分类: Biophysics; Biotechnology & Applied Microbiology; Chemistry; Electrochemistry; Science & Technology - Other Topics
文章类型: Article
所属项目编号: National Natural Science Foundation of China [21375053, 21405066] ; Specialized Research Fund for the Doctorial Program of Higher Education [20130211110039]
所属项目名称: 国家自然科学基金项目 ; 高等学校博士学科点专项科研基金
项目资助者: NSFC ; MOE
语种: 英语
DOI: 10.1016/j.bios.2016.05.044
ISSN号: 0956-5663
WOS记录号: WOS:000382410100062
EI记录号: 20162302459605
PM记录号: 27208479
BIOSIS记录号: BCI:BCI201600759782
IR记录号: WOS:000382410100062
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内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/180597
Appears in Collections:化学化工学院_期刊论文

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Recommended Citation:
Zuo, XW,Zhang, HG,Zhu, Q,et al. A dual-color fluorescent biosensing platform based on WS2 nanosheet for detection of Hg2+ and Ag+[J]. BIOSENSORS & BIOELECTRONICS,2016,85:464-470.
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