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题名: Bacterial community of saliva in adults with and without periodontitis
作者: Zhou, JY; Jiang, N; Jiao, KL; Yu, ZH; Zheng, X; Zhang, JM; Wu, F; Li, JP; Li, ZQ
收录类别: SCIE
出版日期: 2016
刊名: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
卷号: 9, 期号:1-8, 页码:16192-16198
出版者: E-CENTURY PUBLISHING CORP
出版地: MADISON
英文摘要: Objective: The studies of microbial polymorphism of periodontitis were limited and mainly focused on the subgingival plaque. This study was to compare the bacterial community in the saliva of adults with and without periodontitis. Methods: 29 adults samples (15 periodontitis and 14 healthy) who lived in same place were selected. 16S rDNA cloning library technology, ClustalX2, and Mothur v. 1.32.1ect. software and the vegan package of R. LDA Effect Size (LEfSe) were used to compare the bacterial community in the saliva. Results: The major phyla were similar in adults with and without periodontitis. Especially, the genus Prevotella was considered to be the feature in periodontitis samples, while the proportion of Lactobacillus and Granulicatella were lower in adults with periodontitis. Conclusions: These results indicate that the change of the bacterial community at the lower taxonomic levels in saliva of adults may be one pathogenic factor of the periodontitis. This would be taken into account in further treatment or prevention of the periodontitis.
关键词: Periodontitis ; bacterial community ; 16S rDNA cloning library
作者部门: [Zhou, Jianye ; Jiao, Kangli ; Zheng, Xin ; Zhang, Jumei ; Li, Zhiqiang] Northwest Univ Nationalities, Key Lab Oral Dis Gansu Prov, Key Lab Stomatol State Ethn Affairs Commiss, Lanzhou 730030, Gansu, Peoples R China ; [Jiang, Nan] Chinese Acad Sci, Inst Appl Ecol, Shenyang 110016, Liaoning, Peoples R China ; [Yu, Zhanhai ; Wu, Fang ; Li, Junping] Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Gansu, Peoples R China
通讯作者: Li, ZQ (reprint author), Northwest Univ Nationalities, Key Lab Oral Dis Gansu Prov, Key Lab Stomatol State Ethn Affairs Commiss, Lanzhou 730030, Gansu, Peoples R China.
学科分类: Research & Experimental Medicine
文章类型: Article
所属项目编号: National Natural Science Foundation of China (NSFC) [31360124/C0309, 31560159/C0309] ; Science and Technology Support Project in Gansu Province [144WCGA167]
所属项目名称: 国家自然科学基金项目 ; 国家科技支撑计划 ; 甘肃省科技支撑计划
项目资助者: NSFC ; MOST ; GSSTD
语种: 英语
ISSN号: 1940-5901
WOS记录号: WOS:000385837700138
IR记录号: WOS:000385837700138
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内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/189088
Appears in Collections:口腔医学院_期刊论文

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Recommended Citation:
Zhou, JY,Jiang, N,Jiao, KL,et al. Bacterial community of saliva in adults with and without periodontitis[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2016,9(1-8):16192-16198.
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