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题名: The relationship between serum uric acid and metabolic syndrome in premenopausal and postmenopausal women in the Jinchang Cohort
作者: He, SJ; Chan, C; Xie, ZD; Shi, D; Hu, XB; Li, HY; Wang, D; Wang, MZ; Bai, YN
收录类别: SCIE ; PubMed ; MEDLINE
出版日期: 2017-02
刊名: GYNECOLOGICAL ENDOCRINOLOGY
卷号: 33, 期号:1-2, 页码:141-144
出版者: TAYLOR & FRANCIS
出版地: ABINGDON
英文摘要: The aim of the study was to explore the association between serum uric acid (SUA) and metabolic syndrome (MetS) in premenopausal and postmenopausal women in the Jinchang Cohort. We studied 3808 female Jinchuan Nonferrous Metals Corporation workers aged 40-60 years. Cohort data from epidemiological surveys and medical exams were used. MetS was defined using the 2009 Joint Interim Society criteria. The relationship between SUA and MetS was evaluated using multiple logistic regression after adjusting for potential confounders. MetS and hyperuricemia were more prevalent in postmenopausal women than premenopausal ones (35.3% versus 15.2% and 9.2% versus 4.2%, respectively). Premenopausal and postmenopausal women with hyperuricemia had 2.81 (95% CI: 1.72-4.61) and 2.10 (95% CI: 1.44-3.08), respectively, times the odds of having MetS than their counterparts without hyperuricemia. Even within normal SUA quartiles, only premenopausal women in the highest and second-highest quartile had 3.57 (95% CI: 2.24-5.68) and 2.78 (95% CI: 1.71-4.50), respectively, times the odds of having MetS than those in the lowest quartile. Even in the normal range, the odds ratios for MetS increased gradually according to SUA levels in all women (P-trend<0.001). In conclusion, there was a significant correlation between SUA levels and MetS, and the association was stronger in premenopausal women than postmenopausal ones.
关键词: Jinchang Cohort ; metabolic syndrome ; postmenopausal ; premenopausal ; uric acid
作者部门: [He, Shi-Jiao ; Xie, Zhi-Dong ; Shi, Dian ; Hu, Xiao-Bin ; Wang, Min-Zhen ; Bai, Ya-Na] Lanzhou Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Lanzhou 730000, Peoples R China ; [Chan, Cynthia ; Wang, Dennis] Yale Univ, Sch Publ Hlth, New Haven, CT USA ; [Li, Hai-Yan] Jinchuan Workers Hosp, Jinchang, Gansu, Peoples R China
通讯作者: Bai, YN (reprint author), Lanzhou Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Lanzhou 730000, Peoples R China.
学科分类: Endocrinology & Metabolism; Obstetrics & Gynecology
文章类型: Article
所属项目编号: Project of Science and Technology of the Jinchuan Nonferrous Metals Corporation [JKB20120013]
语种: 英语
DOI: 10.1080/09513590.2016.1214261
ISSN号: 0951-3590
WOS记录号: WOS:000395036200013
PM记录号: 27558970
IR记录号: WOS:000395036200013
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内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/189124
Appears in Collections:公共卫生学院_期刊论文

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Recommended Citation:
He, SJ,Chan, C,Xie, ZD,et al. The relationship between serum uric acid and metabolic syndrome in premenopausal and postmenopausal women in the Jinchang Cohort[J]. GYNECOLOGICAL ENDOCRINOLOGY,2017,33(1-2):141-144.
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