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题名: A "turn-on'' fluorescent probe for the detection of Cu2+ in living cells based on a signaling mechanism of N=N isomerization
作者: Cao, S; Jin, QY; Geng, L; Mu, LY; Dong, SL
收录类别: SCIE ; CPCI-S
出版日期: 2016-07-01
英文摘要: A novel fluorescent probe A based on coumarin associated with a N=N double bond was conveniently designed and synthesized for Cu2+, and both rapid colorimetric and fluorescence turn-on detection can be achieved, showing a visible color change from pink to yellow and a significant fluorescence enhancement, respectively. The probe exhibits high selectivity toward Cu2+ over other metal ions and excellent sensitivity with a detection limit of 20 nM, and it can be monitored in a wide range of pH (3-10) in aqueous systems. Besides, the probe has been applied in living cells.
作者部门: [Cao, Shuo ; Jin, Qiaoying ; Geng, Lin ; Mu, Lingyun ; Dong, Shouliang] Lanzhou Univ, Sch Life Sci, Inst Biochem & Mol Biol, 222 Tianshui South Rd, Lanzhou 730000, Peoples R China ; [Jin, Qiaoying] Lanzhou Univ, Hosp 2, Med Genet Lab, Lanzhou 730030, Peoples R China ; [Jin, Qiaoying] Key Lab Digest Syst Tumors Gansu Prov, Lanzhou 730030, Peoples R China ; [Dong, Shouliang] Key Lab Preclin Study New Drugs Gansu Prov, 222 Tianshui South Rd, Lanzhou 730000, Peoples R China
通讯作者: Dong, SL (reprint author), Lanzhou Univ, Sch Life Sci, Inst Biochem & Mol Biol, 222 Tianshui South Rd, Lanzhou 730000, Peoples R China. ; Dong, SL (reprint author), Key Lab Preclin Study New Drugs Gansu Prov, 222 Tianshui South Rd, Lanzhou 730000, Peoples R China.
学科分类: Chemistry
会议录: NEW JOURNAL OF CHEMISTRY
卷号: 40
期号: 7
页码: 6264-6269
出版者: ROYAL SOC CHEMISTRY
出版地: CAMBRIDGE
语种: 英语
DOI: 10.1039/c5nj03649f
ISSN号: 1144-0546
WOS记录号: WOS:000385869600075
IR记录号: WOS:000385869600075
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内容类型: 会议论文
URI标识: http://ir.lzu.edu.cn/handle/262010/189628
Appears in Collections:生命科学学院_会议论文

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Cao, S,Jin, QY,Geng, L,et al. A "turn-on'' fluorescent probe for the detection of Cu2+ in living cells based on a signaling mechanism of N=N isomerization[C]. 见:.
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