兰州大学机构库 >化学化工学院
One-Pot Multicomponent Mechanosynthesis of Polysubstituted trans-2,3-Dihydropyrroles and Pyrroles from Amines, Alkyne Esters, and Chalcones
Xu, H; Liu, HW; Chen, K; Wang, GW; Wang, GW (reprint author), Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, iChEM Collaborat Innovat Ctr Chem Energy Mat, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China.; Wang, GW (reprint author), Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China.; Wang, GW (reprint author), Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China.
收录类别SCIE ; PUBMED
2018-06-01
发表期刊JOURNAL OF ORGANIC CHEMISTRY
卷号83期号:1页码:6035-6049
出版者AMER CHEMICAL SOC
出版地WASHINGTON
摘要An efficient and practical one-pot multicomponent reaction of amines with alkyne esters and chalcones promoted by I-2/PhI(OAc)(2) has been developed under solvent-free ball-milling conditions to afford a variety of polysubstituted trans-2,3-dihydropyrroles in moderate to good yields. The present method features a short reaction time, mild reaction conditions, broad substrate scope, and feasibility of large-scale synthesis. Intriguingly, this protocol can also furnish the corresponding synthetically more attractive pyrroles with the addition of an oxidant in a one-pot way.
作者部门[Xu, Hui;
Liu, Hong-Wei;
Chen, Kuan;
Wang, Guan-Wu] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, iChEM Collaborat Innovat Ctr Chem Energy Mat, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China;
[Xu, Hui;
Liu, Hong-Wei;
Chen, Kuan;
Wang, Guan-Wu] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China;
[Wang, Guan-Wu] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China
学科领域Chemistry
所属项目编号National Natural Science Foundation of China [21372211] ; Strategic Priority Research Program of the Chinese Academy of Sciences [XDB20000000]
资助项目国家自然科学基金项目
项目资助者NSFC
DOI10.1021/acs.joc.8b00665
ISSN0022-3263
文章类型Article
语种英语
WOS记录号WOS:000434367700015
PM记录号29745226
第一机构
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文献类型期刊论文
条目标识符http://ir.lzu.edu.cn/handle/262010/196912
Collection化学化工学院
通讯作者Wang, GW (reprint author), Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, iChEM Collaborat Innovat Ctr Chem Energy Mat, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China.; Wang, GW (reprint author), Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China.; Wang, GW (reprint author), Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China.
Recommended Citation:
GB/T 7714
Xu, H,Liu, HW,Chen, K,et al. One-Pot Multicomponent Mechanosynthesis of Polysubstituted trans-2,3-Dihydropyrroles and Pyrroles from Amines, Alkyne Esters, and Chalcones[J]. JOURNAL OF ORGANIC CHEMISTRY,2018,83(1):6035-6049.
APA Xu, H.,Liu, HW.,Chen, K.,Wang, GW.,Wang, GW .,...&Wang, GW .(2018).One-Pot Multicomponent Mechanosynthesis of Polysubstituted trans-2,3-Dihydropyrroles and Pyrroles from Amines, Alkyne Esters, and Chalcones.JOURNAL OF ORGANIC CHEMISTRY,83(1),6035-6049.
MLA Xu, H,et al."One-Pot Multicomponent Mechanosynthesis of Polysubstituted trans-2,3-Dihydropyrroles and Pyrroles from Amines, Alkyne Esters, and Chalcones".JOURNAL OF ORGANIC CHEMISTRY 83.1(2018):6035-6049.
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