兰州大学机构库 >基础医学院
Efficacy and safety of carbon-ion radiotherapy for the malignant melanoma: A systematic review
Li, Chengcheng1; Zhang, Qiuning2,3; Li, Zheng2; Feng, Shuangwu1; Luo, Hongtao2; Liu, Ruifeng2; Wang, Lina1; Geng, Yichao1; Zhao, Xueshan1; Yang, Zhen4; Li, Qiang2; Yang, KH(杨克虎)5; Wang, Xiaohu1,2,3
2020-06-10
Source PublicationCANCER MEDICINE
ISSN2045-7634
AbstractMalignant melanomas (MMs) were the fifth most common cancer in men and the sixth most common cancer in women in 2018, respectively. These are characterized by high metastatic rates and poor prognoses. We systematically reviewed safety and efficacy of carbon-ion radiotherapy (CIRT) for treating MMs. Eleven studies were eligible for review, and the data showed that MM patients showed better local control with low recurrence and mild toxicities after CIRT. Survival rates were slightly higher in patients with cutaneous or uveal MMs than in those with mucosal MMs. CIRT in combination with chemotherapy produced higher progression-free survival rates than CIRT only. In younger patients, higher rates of distant metastases of gynecological MMs were observed. The data indicated that CIRT is effective and safe for treating MMs; however, a combination with systemic therapy is recommended to ensure the best possible prognosis for MMs.
Keywordcarbon-ion radiotherapy malignant melanoma systematic review
DOI10.1002/cam4.3134
Indexed BySCIE
Language英语
Funding ProjectLanzhou Innovation and Entrepreneurship Talent Project[2017-RC-23]
WOS Research AreaOncology
WOS SubjectOncology
WOS IDWOS:000539184400001
PublisherWILEY
Original Document TypeReview ; Early Access
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.lzu.edu.cn/handle/262010/405819
Collection基础医学院
Corresponding AuthorWang, Xiaohu
Affiliation1.Lanzhou Univ, Sch Clin Med 1, 1 Donggang West Rd, Lanzhou, Gansu, Peoples R China
2.Chinese Acad Sci, Inst Modern Phys, 1 Donggang West Rd, Lanzhou, Gansu, Peoples R China
3.Lanzhou Heavy Ions Hosp, 1 Donggang West Rd, Lanzhou, Gansu, Peoples R China
4.Lanzhou Univ, Basic Med Coll, Lanzhou, Peoples R China
5.Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, Lanzhou, Peoples R China
First Author AffilicationFirst Clinical School
Corresponding Author AffilicationFirst Clinical School;  School of Nuclear Science and Technology
Recommended Citation
GB/T 7714
Li, Chengcheng,Zhang, Qiuning,Li, Zheng,et al. Efficacy and safety of carbon-ion radiotherapy for the malignant melanoma: A systematic review[J]. CANCER MEDICINE,2020.
APA Li, Chengcheng.,Zhang, Qiuning.,Li, Zheng.,Feng, Shuangwu.,Luo, Hongtao.,...&Wang, Xiaohu.(2020).Efficacy and safety of carbon-ion radiotherapy for the malignant melanoma: A systematic review.CANCER MEDICINE.
MLA Li, Chengcheng,et al."Efficacy and safety of carbon-ion radiotherapy for the malignant melanoma: A systematic review".CANCER MEDICINE (2020).
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