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题名: Two New Asymmetric Sesquiterpene Dimers from the Rhizomes of Ligularia muliensis
作者: Fei, DQ(费冬青); Wu, QH; Li, SG; Gao, K(高坤)
收录类别: SCIE ; PubMed ; MEDLINE ; BIOSIS
出版日期: 2010-04
刊名: CHEMICAL & PHARMACEUTICAL BULLETIN
卷号: 58, 期号:4
出版者: PHARMACEUTICAL SOC JAPAN
出版地: TOKYO
英文摘要: Two new asymmetric eremophilane-type sesquiterpene dimers, ligulamulienin A (1) and B (2), were isolated from the rhizomes of Ligularia muliensis. Their structures were determined based on their spectroscopic data, including IR, EI-MS, HR-electrospray ionization (ESI)-MS, ID and 2D-NMR spectroscopy. The cytotoxicity of compounds 1 and 2 was measured in in vitro human carcinoma (MGC-803), human hepatoma (HEP-G2), and murine sarcoma (S-180) cell lines.
关键词: Ligularia muliensis ; sesquiterpene dimer ; ligulamulienin A ; ligulamulienin B ; cytotoxic activity
作者部门: [Fei, Dong-Qing ; Wu, Qiu-Hong ; Gao, Kun] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China ; [Fei, Dong-Qing] Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China ; [Li, Shi-Gang] Lanzhou Univ, Inst Basic Med, Lanzhou 730000, Peoples R China
通讯作者: Gao, K (reprint author), Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
学科分类: Pharmacology & Pharmacy;Chemistry
文章类型: Article
所属项目编号: National Basic Research Program of China [2007CB108903] ; National Natural Science Foundation of China [20621091]
所属项目名称: 国家自然科学基金项目 ; 国家重点基础研究发展计划以及国家重大科学研究计划(973计划)
项目资助者: NSFC ; MOST
语种: 英语
ISSN号: 0009-2363
WOS记录号: WOS:000276065200006
PM记录号: 20410625
BIOSIS记录号: BIOSIS:PREV201000212704
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内容类型: 期刊论文
URI标识: http://ir.lzu.edu.cn/handle/262010/75933
Appears in Collections:化学化工学院_期刊论文

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Fei, DQ; Wu, QH; Li, SG; Gao, K.Two New Asymmetric Sesquiterpene Dimers from the Rhizomes of Ligularia muliensis,CHEMICAL & PHARMACEUTICAL BULLETIN,2010,58(4):
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