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YC-1 potentiates the antitumor activity of gefitinib by inhibiting HIF-1 alpha and promoting the endocytic trafficking and degradation of EGFR in gefitinib-resistant non-small-cell lung cancer cells
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2020, 卷号: 874
Authors:
Hu, Hui
;
Miao, XK(苗小康)
;
Li, Jing-Yi
;
Zhang, Xiao-Wei
;
Xu, Jing-Jie
;
Zhang, Jing-Ying
;
Zhou, Tian-Xiong
;
Hu, Ming-Ning
;
Yang, Wen-Le
;
Mou, LY(牟凌云)
...
Hu, Hui
;
Miao, XK(苗小康)
;
Li, Jing-Yi
;
Zhang, Xiao-Wei
;
Xu, Jing-Jie
;
Zhang, Jing-Ying
;
Zhou, Tian-Xiong
;
Hu, Ming-Ning
;
Yang, Wen-Le
;
Mou, LY(牟凌云)
Favorite
  |  
View/Download:1/0
  |  
Submit date:2020/08/20
NSCLC
Gefitinib
YC-1
EGFR
HIF-1 alpha
Degradation
CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor
期刊论文
CANCERS, 2019, 卷号: 11, 期号: 4
Authors:
Liu, Bin
;
Song, Shanshan
;
Setroikromo, Rita
;
Chen, Siwei
;
Hu, Wenteng
;
Chen, Deng
;
van der Wekken, Anthonie J.
;
Melgert, Barbro N.
;
Timens, Wim
;
van den Berg, Anke
...
Liu, Bin
;
Song, Shanshan
;
Setroikromo, Rita
;
Chen, Siwei
;
Hu, Wenteng
;
Chen, Deng
;
van der Wekken, Anthonie J.
;
Melgert, Barbro N.
;
Timens, Wim
;
van den Berg, Anke
;
Saber, Ali
;
Haisma, Hidde J.
Favorite
  |  
View/Download:3/0
  |  
Submit date:2019/10/21
epidermal growth factor receptor (EGFR)
CXCR7
KRAS
lung cancer
targeted therapy
gene editing
Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18
Authors:
Bing, Zhitong
;
Cheng, Zhiyuan
;
Shi, Danfeng
;
Liu, Xinkui
;
Tian, JH(田金徽)
;
Yao, XJ(姚小军)
;
Zhang, Jingyun
;
Wang, Yongfeng
;
Yang, KH(杨克虎)
Favorite
  |  
View/Download:5/0
  |  
Submit date:2019/10/28
Systems pharmacology
Fuzhengkangai formula
Herbal medicines
Molecular docking
吉非替尼与化疗一线治疗晚期非鳞非小细胞肺癌患者的疗效分析
学位论文
硕士, 兰州: 兰州大学, 2018
Authors:
张皓珍
Favorite
  |  
View/Download:8/0
  |  
Submit date:2019/01/17
吉非替尼
化疗
非鳞非小细胞肺癌
表皮生长因子受体
Gefitinib enhances sensitivity of endometrial cancer cells to progestin therapy via dual-specificity phosphatase 1
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 14, 页码: 115360-115369
Authors:
Yang, Y
;
Zhou, JY
;
Li, XP
;
Zhao, LJ
;
Cheng, Y
;
Lin, YY
;
Wang, JQ
;
Wei, LH
;
Dong, YF
;
Wang, JL
...
Yang, Y
;
Zhou, JY
;
Li, XP
;
Zhao, LJ
;
Cheng, Y
;
Lin, YY
;
Wang, JQ
;
Wei, LH
;
Dong, YF
;
Wang, JL
;
Wang, JL (reprint author), Peking Univ, Peoples Hosp, Dept Obstet & Gynecol, Beijing, Peoples R China.
Favorite
  |  
View/Download:35/0
  |  
Submit date:2018/09/28
endometrial cancer
gefitinib
MPA
DUSP1
targeted therapy
Gefitinib enhances radiotherapeutic effects of I-131-hEGF targeted to EGFR by increasing tumor uptake of hEGF in tumor xenografts
期刊论文
NUCLEAR MEDICINE AND BIOLOGY, 2017, 卷号: 48, 页码: 63-68
Authors:
Lu, X
;
He, P
;
Luo, ZQ
;
Zhang, XL
;
Zhang, XL (reprint author), Capital Med Univ, Beijing Anzhen Hosp, Dept Nucl Med, Beijing, Peoples R China.
;
He, P (reprint author), Peking Univ, Med Isotopes Res Ctr, Beijing, Peoples R China.
Favorite
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View/Download:36/0
  |  
Submit date:2018/01/19
Gefitinib
hEGF
131I
EGFR
Radiotherapy
Detection of microRNA-200b may predict the inhibitory effect of gefitinib on non-small cell lung cancer and its potential mechanism
期刊论文
ONCOLOGY LETTERS, 2016, 卷号: 12, 期号: 6, 页码: 5349-5355
Authors:
Liu, ZW
;
Yao, LQ
;
Tan, BY
;
Li, L
;
Chen, BJ
;
Liu, ZW (reprint author), Lanzhou Univ, Hosp 1, Dept Med Lab Ctr, 1 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.
Favorite
  |  
View/Download:39/0
  |  
Submit date:2017/05/08
non-small cell lung cancer
gefitinib
microRNA
IGF-1R
Combining Whole-Brain Radiotherapy with Gefitinib/Erlotinib for Brain Metastases from Non-Small-Cell Lung Cancer: A Meta-Analysis
期刊论文
BIOMED RESEARCH INTERNATIONAL, 2016
Authors:
Zheng, MH
;
Sun, HT
;
Xu, JG
;
Yang, G
;
Huo, LM
;
Zhang, P
;
Tian, JH(田金徽)
;
Yang, KH(杨克虎)
;
Yang, KH (reprint author), Lanzhou Univ, Evidence Based Med Ctr, Lanzhou 730000, Peoples R China.
;
Yang, KH (reprint author), Key Lab Evidence Based Med & Knowledge Translat G, Lanzhou 730000, Peoples R China.
...
Zheng, MH
;
Sun, HT
;
Xu, JG
;
Yang, G
;
Huo, LM
;
Zhang, P
;
Tian, JH(田金徽)
;
Yang, KH(杨克虎)
;
Yang, KH (reprint author), Lanzhou Univ, Evidence Based Med Ctr, Lanzhou 730000, Peoples R China.
;
Yang, KH (reprint author), Key Lab Evidence Based Med & Knowledge Translat G, Lanzhou 730000, Peoples R China.
Favorite
  |  
View/Download:33/0
  |  
Submit date:2017/01/09
TPCA-1 Is a Direct Dual Inhibitor of STAT3 and NF-kappa B and Regresses Mutant EGFR-Associated Human Non-Small Cell Lung Cancers
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2014, 卷号: 13, 期号: 3, 页码: 617-629
Authors:
Nan, J
;
Du, YP
;
Chen, X
;
Bai, QF
;
Wang, YX
;
Zhang, XX
;
Zhu, N
;
Zhang, J
;
Hou, JW
;
Wang, Q
...
Nan, J
;
Du, YP
;
Chen, X
;
Bai, QF
;
Wang, YX
;
Zhang, XX
;
Zhu, N
;
Zhang, J
;
Hou, JW
;
Wang, Q
;
Yang, JB(杨金波)
;
Yang, JB (reprint author), Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Gansu, Peoples R China.
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  |  
View/Download:118/0
  |  
Submit date:2015/12/14
吉非替尼治疗非小细胞肺癌的meta分析
期刊论文
中国肺癌杂志, 2011, 卷号: 14, 期号: 4, 页码: 351-357
Authors:
郭继武
;
马彬
;
周慧银
;
王瑶
;
张圆
Favorite
  |  
View/Download:14/0
  |  
Submit date:2016/09/09
吉非替尼
肺肿瘤
Meta分析