兰州大学机构库

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Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 18, 页码: 824-832
Authors:  Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM...Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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antimicrobial peptides  intramolecular cyclization  click chemistry  stability  antimicrobial activity  secondary structure  mechanism of action  
Antimicrobial activity and stability of the D-amino acid substituted derivatives of antimicrobial peptide polybia-MPI 期刊论文
AMB Express, 2016, 卷号: 6
Authors:  Zhao, YY;  Zhang, M;  Qiu, S;  Wang, JY;  Peng, JX;  Zhao, P;  Zhu, RR;  Wang, HL;  Li, Y;  Wang, KR...Zhao, YY;  Zhang, M;  Qiu, S;  Wang, JY;  Peng, JX;  Zhao, P;  Zhu, RR;  Wang, HL;  Li, Y;  Wang, KR;  Yan, WJ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Antimicrobial peptide  Polybia-MPI  Stability  D-Amino acid substitution  
阳离子抗菌肽polybia-MPI抗真菌活性、作用机制、稳定性及构效关系研究 学位论文
硕士, 兰州: 兰州大学, 2016
Authors:  赵妍妍
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抗菌肽  polybia-MPI  抗真菌活性  细胞膜完整性  构效关系  稳定性  细胞毒性  作用机制  
Functional properties of a novel hybrid antimicrobial peptide NS: potent antitumor activity and efficient plasmid delivery 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2014, 卷号: 20, 期号: 10, 页码: 785-793
Authors:  Zhang, Y;  Song, JJ;  Zhang, W;  Liang, RR;  Ma, YY;  Zhang, L;  Wei, XJ;  Ni, JM(倪京满);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China....Zhang, Y;  Song, JJ;  Zhang, W;  Liang, RR;  Ma, YY;  Zhang, L;  Wei, XJ;  Ni, JM(倪京满);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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Ns  Antitumor Activity  Membrane Disruption  Dna Interaction  Plasmid Transfection  
Dual antifungal properties of cationic antimicrobial peptides polybia-MPI: Membrane integrity disruption and inhibition of biofilm formation 期刊论文
PEPTIDES, 2014, 卷号: 56, 页码: 22-29
Authors:  Wang, KR;  Yan, JX;  Dang, W;  Xie, JQ;  Yan, B;  Yan, WJ;  Sun, MY;  Zhang, BZ(张邦治);  Ma, MX;  Zhao, YY...Wang, KR;  Yan, JX;  Dang, W;  Xie, JQ;  Yan, B;  Yan, WJ;  Sun, MY;  Zhang, BZ(张邦治);  Ma, MX;  Zhao, YY;  Jia, FJ;  Zhu, RR;  Chen, W;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Antifungal activity  Antimicrobial peptide  Polybia-MPI Biofilm formation  
Membrane Perturbation Action Mode and Structure-Activity Relationships of Protonectin, a Novel Antimicrobial Peptide from the Venom of the Neotropical Social Wasp Agelaia pallipes pallipes 期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 卷号: 57, 期号: 10, 页码: 4632-4639
Authors:  Wang, KR;  Dang, W;  Yan, JX;  Chen, R;  Liu, X;  Yan, WJ;  Zhang, BZ(张邦治);  Xie, JQ;  Zhang, JD;  Wang, R(王锐)...Wang, KR;  Dang, W;  Yan, JX;  Chen, R;  Liu, X;  Yan, WJ;  Zhang, BZ(张邦治);  Xie, JQ;  Zhang, JD;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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Design of an Acid-Activated Antimicrobial Peptide for Tumor Therapy 期刊论文
MOLECULAR PHARMACEUTICS, 2013, 卷号: 10, 期号: 8, 页码: 2934-2941
Authors:  Song, JJ;  Zhang, W;  Kai, M;  Chen, JB;  Liang, RR;  Zheng, X;  Li, GL;  Zhang, BZ(张邦治);  Wang, KR;  Zhang, Y...Song, JJ;  Zhang, W;  Kai, M;  Chen, JB;  Liang, RR;  Zheng, X;  Li, GL;  Zhang, BZ(张邦治);  Wang, KR;  Zhang, Y;  Yang, ZB;  Ni, JM(倪京满);  Wang, R(王锐);  Ni, JM (reprint author), Lanzhou Univ, Sch Pharm, 222 South Tianshui Rd, Lanzhou 730000, Peoples R China.
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antimicrobial peptide  antitumor  acid activate  low toxicity  enzymatic stability  
Membrane active antimicrobial activity and molecular dynamics study of a novel cationic antimicrobial peptide polybia-MPI, from the venom of Polybia paulista 期刊论文
PEPTIDES, 2013, 卷号: 39, 页码: 80-88
Authors:  Wang, KR;  Yan, JX;  Dang, W;  Liu, X;  Chen, R;  Zhang, JD;  Zhang, BZ(张邦治);  Zhang, W;  Kai, M;  Yan, WJ...Wang, KR;  Yan, JX;  Dang, W;  Liu, X;  Chen, R;  Zhang, JD;  Zhang, BZ(张邦治);  Zhang, W;  Kai, M;  Yan, WJ;  Yang, ZB;  Xie, JQ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci,Inst Biochem & Mol Biol, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Resistant bacteria  Polybia-MPI  Membrane perturbation  Molecular dynamics study  
Membrane-Active Action Mode of Polybia-CP, a Novel Antimicrobial Peptide Isolated from the Venom of Polybia paulista 期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 卷号: 56, 期号: 6, 页码: 3318-3323
Authors:  Wang, KR;  Yan, JX;  Chen, R;  Dang, W;  Zhang, BZ(张邦治);  Zhang, W;  Song, JJ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Sch Life Sci,Inst Biochem & Mol Biol, Lanzhou 730000, Peoples R China.
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Membrane active antitumor activity of NK-18, a mammalian NK-lysin-derived cationic antimicrobial peptide 期刊论文
BIOCHIMIE, 2012, 卷号: 94, 期号: 1, 页码: 184-191
Authors:  Yan, JX;  Wang, KR;  Chen, R;  Song, JJ;  Zhang, BZ(张邦治);  Dang, W;  Zhang, W;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, 222 S Tianshui Rd, Lanzhou 730000, Peoples R China.
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Antimicrobial peptide  Antitumor  NK-18  Core region  Action mechanism