兰州大学机构库

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Design, synthesis and antineoplastic activity of novel 20(S)-acylthiourea derivatives of camptothecin 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 187
Authors:  Yang, Cheng-Jie;  Li, Bin;  Zhang, Zhi-Jun;  Gao, Jian-Mei;  Wang, Mei-Juan;  Zhao, Xiao-Bo;  Song, Zi-Long;  Liu, YQ(刘映前);  Li, Hu;  Chen, Yuyuan...Yang, Cheng-Jie;  Li, Bin;  Zhang, Zhi-Jun;  Gao, Jian-Mei;  Wang, Mei-Juan;  Zhao, Xiao-Bo;  Song, Zi-Long;  Liu, YQ(刘映前);  Li, Hu;  Chen, Yuyuan;  Lee, Kuo-Hsiung;  Morris-Natschke, Susan L.;  Xu, Chuanrui
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Camptothecin  Acylthioureas  Topoisomerase I  Cytotoxicity  
新型喹啉类Top I抑制剂的设计、合成与抗肿瘤活性研究 学位论文
硕士, 兰州: 兰州大学, 2018
Authors:  徐小山
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喹啉  Top I抑制剂  喜树碱  ARC-111  茚并异喹啉  
Treatment mechanism of matrine in combination with irinotecan for colon cancer 期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 14, 页码: 2300-2304
Authors:  Duan, L;  Deng, LJ;  Wang, DB;  Ma, SC;  Li, CM;  Zhao, D;  Zhao, D (reprint author), Lanzhou Univ, Hosp 1, Dept Oncol, 1 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.
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matrine  irinotecan  colon cancer  HT29 cells  apoptosis  
Conjugates of podophyllotoxin and norcantharidin as dual inhibitors of topoisomeraseⅡ and protein phosphatase 2A. 期刊论文
European journal of medicinal chemistry, 2016, 卷号: 123, 页码: 568-576
Authors:  Tang, Zhen-Bo;  Chen, Yao-Zhang;  Zhao, Jie;  Guan, Xiao-Wen;  Bo, Yong-Xin;  Chen, Shi-Wu;  Hui, Ling;  Chen, SW (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.;  Hui, L (reprint author), Gen Hosp Lanzhou Mil Command, Ctr Med Expt, Lanzhou 730050, Peoples R China.
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Podophyllotoxin  Cantharidin  TOP-II  PP2A  Cell-cycle arrest  
Design, synthesis, cytotoxic activity and molecular docking studies of new 20(S)-sulfonylamidine camptothecin derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 115, 页码: 109-120
Authors:  Song, ZL;  Wang, MJ;  Li, LL;  Wu, D;  Wang, YH;  Yan, LT;  Morris-Natschke, SL;  Liu, YQ;  Zhao, YL;  Wang, CY...Song, ZL;  Wang, MJ;  Li, LL;  Wu, D;  Wang, YH;  Yan, LT;  Morris-Natschke, SL;  Liu, YQ;  Zhao, YL;  Wang, CY;  Liu, HX;  Goto, M;  Liu, H;  Zhu, GX;  Lee, KH;  Liu, HX (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.;  Lee, KH (reprint author), Univ N Carolina, Eshelman Sch Pharm, Nat Prod Res Labs, Chapel Hill, NC 27599 USA.;  Lee, KH (reprint author), China Med Univ & Hosp, Chinese Med Res & Dev Ctr, Taichung, Taiwan.
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Camptothecin  Cytotoxic activity  Molecular docking  Sulfonylamidine  Synthesis  
Perspectives on Biologically Active Camptothecin Derivatives 期刊论文
MEDICINAL RESEARCH REVIEWS, 2015, 卷号: 35, 期号: 4, 页码: 753-789
Authors:  Liu, YQ;  Li, WQ;  Morris-Natschke, SL;  Qian, KD;  Yang, L;  Zhu, GX;  Wu, XB;  Chen, AL;  Zhang, SY;  Nan, X...Liu, YQ;  Li, WQ;  Morris-Natschke, SL;  Qian, KD;  Yang, L;  Zhu, GX;  Wu, XB;  Chen, AL;  Zhang, SY;  Nan, X;  Lee, KH;  Lee, KH (reprint author), Univ N Carolina, Eshelman Sch Pharm, Nat Prod Res Labs, Chapel Hill, NC 27599 USA.
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camptothecins  DNA topoisomerase I  biological activities  structure-activity relationship  
Recent Progress on C-4-Modified Podophyllotoxin Analogs as Potent Antitumor Agents 期刊论文
Medicinal Research Reviews, 2015, 卷号: 35, 期号: 1, 页码: 1-62
Authors:  Liu, YQ(刘映前);  Tian, J;  Qian, K;  Zhao, XB;  Morris-Natschke, SL;  Yang, L;  Nan, X;  Tian, X;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China....Liu, YQ(刘映前);  Tian, J;  Qian, K;  Zhao, XB;  Morris-Natschke, SL;  Yang, L;  Nan, X;  Tian, X;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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podophyllotoxin  cytotoxic agents  C-4 position  reviews  
Design and synthesis of novel spin-labeled camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 22, 页码: 6453-6458
Authors:  Zhao, XB;  Wu, D;  Wang, MJ;  Goto, M;  Morris-Natschke, SL;  Liu, YQ(刘映前);  Wu, XB;  Song, ZL;  Zhu, GX;  Lee, KH...Zhao, XB;  Wu, D;  Wang, MJ;  Goto, M;  Morris-Natschke, SL;  Liu, YQ(刘映前);  Wu, XB;  Song, ZL;  Zhu, GX;  Lee, KH;  Liu, YQ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Camptothecin  C-20 position  Cytotoxic activity  Spin-labeled  
Critical Role for Lysine 685 in Gene Expression Mediated by Transcription Factor Unphosphorylated STAT3 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 卷号: 289, 期号: 44, 页码: 30763-30771
Authors:  Dasgupta, M;  Unal, H;  Willard, B;  Yang, JB(杨金波);  Karnik, SS;  Stark, GR;  Stark, GR (reprint author), Cleveland Clin, Dept Mol Genet, Cleveland, OH 44195 USA.
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pH-responsive polymer-drug conjugates as multifunctional micelles for cancer-drug delivery 期刊论文
NANOTECHNOLOGY, 2014, 卷号: 25, 期号: 33, 页码: -
Authors:  Kang, Y;  Ha, W;  Liu, YQ(刘映前);  Ma, Y;  Fan, MM;  Ding, LS;  Zhang, S;  Li, BJ;  Kang, Y (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Key Lab Mt Ecol Restorat & Bioresource Utilizat, Chengdu 610041, Peoples R China.
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micelle  anticancer  drug carrier  podophyllotoxin  pH-responsible cleavage