兰州大学机构库

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Novel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 3, 页码: 690-702
Authors:  Xie, JQ;  Zhao, Q;  Li, SS;  Yan, ZB;  Li, J;  Li, Y;  Mou, LY;  Zhang, BZ;  Yang, WL;  Miao, XK...Xie, JQ;  Zhao, Q;  Li, SS;  Yan, ZB;  Li, J;  Li, Y;  Mou, LY;  Zhang, BZ;  Yang, WL;  Miao, XK;  Jiang, XX;  Wang, R;  Wang, R (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou, Guangdong, Peoples R China.
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analogs  antibiofilm  antimicrobial peptides  multidrug-resistant bacteria  stability  
MEL-N16: A Series of Novel Endomorphin Analogs with Good Analgesic Activity and a Favorable Side Effect Profile 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 17, 页码: 2180-2193
Authors:  Liu, X;  Zhao, L;  Wang, Y;  Zhou, JJ;  Wang, D;  Zhang, YX;  Zhang, XH;  Wang, ZJ;  Yang, DX;  Mou, LY...Liu, X;  Zhao, L;  Wang, Y;  Zhou, JJ;  Wang, D;  Zhang, YX;  Zhang, XH;  Wang, ZJ;  Yang, DX;  Mou, LY;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.
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antinociception  blood-brain barrier  endomorphin  side effect  stability  opioid peptide  
Endomorphin-1 analogs containing alpha-methyl-beta-amino acids exhibit potent analgesic activity after peripheral administration 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 12, 期号: 23, 页码: 4951-4955
Authors:  Wang, Y;  Yang, JX;  Liu, X;  Zhao, L;  Yang, DX;  Zhou, JJ;  Wang, D;  Mou, LY;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Dept Pharmacol, Inst Biochem & Mol Biol,Sch Basic Med Sci, Lanzhou 730000, Peoples R China....Wang, Y;  Yang, JX;  Liu, X;  Zhao, L;  Yang, DX;  Zhou, JJ;  Wang, D;  Mou, LY;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Dept Pharmacol, Inst Biochem & Mol Biol,Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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beta-Arrestin 1 has an essential role in neurokinin-1 receptor-mediated glioblastoma cell proliferation and G(2)/M phase transition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 21, 页码: 8933-8947
Authors:  Zhang, YX;  Li, XF;  Yuan, GQ;  Hu, H;  Song, XY;  Li, JY;  Miao, XK;  Zhou, TX;  Yang, WL;  Zhang, XW...Zhang, YX;  Li, XF;  Yuan, GQ;  Hu, H;  Song, XY;  Li, JY;  Miao, XK;  Zhou, TX;  Yang, WL;  Zhang, XW;  Mou, LY;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Inst Biochem & Mol Biol, Sch Life Sci, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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arrestin  cell cycle  cell proliferation  cyclin-dependent kinase (CDK)  glioblastoma  neurokinin-1 receptor  
Neurokinin-1 receptor mediated breast cancer cell migration by increased expression of MMP-2 and MMP-14 期刊论文
EUROPEAN JOURNAL OF CELL BIOLOGY, 2016, 卷号: 95, 期号: 1-10, 页码: 368-377
Authors:  Li, JY;  Zeng, Q;  Zhang, YX;  Li, XF;  Hu, H;  Miao, XK;  Yang, WL;  Zhang, W;  Song, XY;  Mou, LY...Li, JY;  Zeng, Q;  Zhang, YX;  Li, XF;  Hu, H;  Miao, XK;  Yang, WL;  Zhang, W;  Song, XY;  Mou, LY;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Inst Biochem & Mol Biol, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Breast cancer  Neurokinin-1 receptor  Hemokinin-1  Cell migration  Matrix metalloproteinases  
Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors 期刊论文
PEPTIDES, 2016, 卷号: 83, 页码: 8-15
Authors:  Zhang, YX;  Li, XF;  Li, JY;  Hu, H;  Miao, XK;  Song, XY;  Yang, WL;  Zeng, Q;  Mou, LY;  Wang, R(王锐)...Zhang, YX;  Li, XF;  Li, JY;  Hu, H;  Miao, XK;  Song, XY;  Yang, WL;  Zeng, Q;  Mou, LY;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Inst Biochem & Mol Biol, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Hemokinin-1  Melanoma  Neurokinin-1 receptor  Cell migration  Matrix metalloproteinases  
Design and Synthesis of a Novel Series of Opioid Dipeptides and Evaluation of Their Analgesic Effect in Vivo 期刊论文
ACTA CHIMICA SINICA, 2016, 卷号: 74, 期号: 1, 页码: 44-48
Authors:  Liu, X;  Zhao, L;  Wang, Y;  Mou, LY;  Zhang, YX;  Zhou, JJ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.;  Wang, R (reprint author), Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China.
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opioid peptide  antinociception  structure-activity relationship  blood-brain barrier  unnatural amino acid  
一类全新阿片样二肽的设计合成及镇痛活性研究 期刊论文
化学学报, 2016, 卷号: 74, 期号: 1, 页码: 44-48
Authors:  刘鑫;  赵龙;  王媛;  牟凌云;  张艺馨;  周静静;  王锐
Favorite  |  View/Download:22/0  |  Submit date:2018/05/28
阿片肽  镇痛  构效关系  血脑屏障  非天然氨基酸  
Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 22, 页码: 5393-5397
Authors:  Liu, X;  Zhao, L;  Wang, Y;  Mou, LY;  Yang, JX;  Zhang, YX;  Wang, D;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Dept Pharmacol,Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Inst Biochem & Mol Biol,Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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Endomorphin  Analgesia  Blood-brain barrier  Unnatural amino acid  
Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria 会议论文
JOURNAL OF PEPTIDE SCIENCE, Datong City, PEOPLES R CHINA, JUN 30-JUL 04, 2014
Authors:  Xie, JQ;  Gou, YM;  Zhao, Q;  Li, SS;  Zhang, W;  Song, JJ;  Mou, LY;  Li, JY;  Wang, KR;  Zhang, BZ...Xie, JQ;  Gou, YM;  Zhao, Q;  Li, SS;  Zhang, W;  Song, JJ;  Mou, LY;  Li, JY;  Wang, KR;  Zhang, BZ;  Yang, WL;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
Favorite  |  View/Download:138/0  |  Submit date:2017/01/17
Multidrug-resistant Bacteria  Cell-penetrating Peptides  Transportan 10  Structure-activity Relationships  Action Mechanism