兰州大学机构库

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Druggable negative allosteric site of P2X3 receptors 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 19, 页码: 4939-4944
Authors:  Wang, J;  Wang, Y;  Cui, WW;  Huang, YC;  Yang, Y;  Liu, Y;  Zhao, WS;  Cheng, XY;  Sun, WS;  Cao, P...Wang, J;  Wang, Y;  Cui, WW;  Huang, YC;  Yang, Y;  Liu, Y;  Zhao, WS;  Cheng, XY;  Sun, WS;  Cao, P;  Zhu, MX;  Wang, R;  Hattori, M;  Yu, Y;  Hattori, M (reprint author), Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Sch Life Sci, Dept Physiol & Biophys,State Key Lab Genet Engn, Shanghai 200438, Peoples R China.;  Yu, Y (reprint author), Shanghai Jiao Tong Univ, Sch Med, Inst Med Sci, Dept Pharmacol & Chem Biol, Shanghai 200025, Peoples R China.;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.;  Yu, Y (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200025, Peoples R China.
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P2X3 receptors  allosteric inhibition  X-ray crystallography  AF-219  AF-353  
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 页码: 988-1002
Authors:  Liu, K;  Fang, LJ;  Sun, HY;  Pan, ZY;  Zhang, JC;  Chen, JT;  Shao, XM;  Wang, W;  Tan, YY;  Ding, ZH...Liu, K;  Fang, LJ;  Sun, HY;  Pan, ZY;  Zhang, JC;  Chen, JT;  Shao, XM;  Wang, W;  Tan, YY;  Ding, ZH;  Ao, LJ;  Wu, CL;  Liu, XQ;  Li, HS;  Wang, R;  Su, W;  Li, HC;  Li, HC (reprint author), Shenzhen Inst Adv Technol, 1068 Xueyuan Blvd, Shenzhen 518055, Guangdong, Peoples R China.;  Su, W (reprint author), Lanzhou Univ, 199 West Donggang Rd, Lanzhou 730020, Gansu, Peoples R China.
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Seneca Valley Virus 3C(pro) abrogates the IRF3-and IRF7-mediated innate immune response by degrading IRF3 and IRF7 期刊论文
VIROLOGY, 2018, 卷号: 518, 期号: 19, 页码: 1-7
Authors:  Xue, Q;  Liu, HS;  Zhu, ZX;  Yang, F;  Ma, LN;  Cai, XP;  Xue, QH;  Zheng, HX;  Zheng, HX (reprint author), Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol,Minist Agr, Natl Foot & Mouth Dis Reference Lab,Key Lab Anim, Lanzhou 730046, Gansu, Peoples R China.
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Seneca Valley Virus  Innate immunity  3C-like protease  IRF3  IRF7  
Prolonged intervals during Mycobacterium tuberculosis subunit vaccine boosting contributes to eliciting immunity mediated by central memory-like T cells 期刊论文
TUBERCULOSIS, 2018, 卷号: 110, 期号: 5-6, 页码: 104-111
Authors:  Bai, CX;  He, JJ;  Niu, HX;  Hu, LN;  Luo, YP;  Liu, X;  Peng, L;  Zhu, BD;  Zhu, BD (reprint author), Lanzhou Univ, Inst Pathogen Biol, Sch Basic Med Sci, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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Mycobacterium tuberculosis  Subunit vaccine  Immunization schedules  Immune memory  Protective efficacy  
Tuberculosis vaccines: Opportunities and challenges 期刊论文
RESPIROLOGY, 2018, 卷号: 23, 期号: 6, 页码: 359-368
Authors:  Zhu, BD;  Dockrell, HM;  Ottenhoff, THM;  Evans, TG;  Zhang, Y;  Zhu, BD (reprint author), Lanzhou Univ, Lanzhou Ctr TB Res, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.;  Zhu, BD (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Pathogen Biol, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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biomarkers  clinical trials  immunity  tuberculosis  vaccines  
Analysis of the Registration Information on Interventions of Acupuncture and Moxibustion Trials in the International Clinical Trials Registry Platform 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018
Authors:  Liu, YL;  Chen, WJ;  Tan, YX;  Yang, XY;  Liu, J;  Lu, TT;  Yan, SY;  He, LY;  Liu, BY;  Liu, BY (reprint author), China Acad Chinese Med Sci, Beijing 100700, Peoples R China....Liu, YL;  Chen, WJ;  Tan, YX;  Yang, XY;  Liu, J;  Lu, TT;  Yan, SY;  He, LY;  Liu, BY;  Liu, BY (reprint author), China Acad Chinese Med Sci, Beijing 100700, Peoples R China.
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Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 18, 页码: 824-832
Authors:  Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM...Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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antimicrobial peptides  intramolecular cyclization  click chemistry  stability  antimicrobial activity  secondary structure  mechanism of action  
The pH stability of foot-and-mouth disease virus 期刊论文
VIROLOGY JOURNAL, 2017, 卷号: 14
Authors:  Yuan, H;  Li, PH;  Ma, XQ;  Lu, ZJ;  Sun, P;  Bai, XW;  Zhang, J;  Bao, HF;  Cao, YM;  Li, D...Yuan, H;  Li, PH;  Ma, XQ;  Lu, ZJ;  Sun, P;  Bai, XW;  Zhang, J;  Bao, HF;  Cao, YM;  Li, D;  Fu, YF;  Chen, YL;  Bai, QF;  Zhang, J;  Liu, ZX;  Liu, ZX (reprint author), Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol, OIE China Foot & Mouth Dis Reference Lab, 1 Xujiaping, Lanzhou 730046, Gansu, Peoples R China.
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FMDV  pH stability  Substitutions  Uncoating  
Immunogenicity and protective efficacy of multistage vaccine candidates (Mtb8.4-HspX and HspX-Mtb8.4) against Mycobacterium tuberculosis infection in mice 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2017, 卷号: 53, 期号: 6, 页码: 83-89
Authors:  Liu, WB;  Li, JJ;  Niu, HX;  Lin, XF;  Li, RY;  Wang, Y;  Xin, Q;  Yu, HJ;  Wu, YM;  Zhu, BD...Liu, WB;  Li, JJ;  Niu, HX;  Lin, XF;  Li, RY;  Wang, Y;  Xin, Q;  Yu, HJ;  Wu, YM;  Zhu, BD;  Tan, JY;  Tan, JY (reprint author), Lanzhou Univ, Sch Basic Med Sci, Gansu Prov Key Lab Evidence Based Med, Lanzhou 7300004, Gansu, Peoples R China.;  Tan, JY (reprint author), Lanzhou Univ, Sch Basic Med Sci, Lanzhou Ctr TB Res, Lanzhou 7300004, Gansu, Peoples R China.;  Zhu, BD (reprint author), Lanzhou Univ, Inst Pathogen Biol, Sch Basic Med Sci, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.;  Tan, JY (reprint author), Sch Basic Med Sci, Immunol, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.;  Tan, JY (reprint author), Sch Basic Med Sci, Gansu Prov Key Lab Evidence Based Med & Clin Tran, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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Mycobacterium tuberculosis  Protein vaccine  Mtb8.4  HspX  Protein sequential order  Antigen dose  
IRE1 alpha/XBP1s branch of UPR links HIF1 alpha activation to mediate ANGII-dependent endothelial dysfunction under particulate matter (PM) 2.5 exposure 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: 6
Authors:  Xu, XD;  Qimuge, AD;  Wang, HL;  Xing, C;  Gu, Y;  Liu, SS;  Xu, H;  Hu, MR;  Song, L;  Song, L (reprint author), Beijing Inst Basic Med Sci, Dept Stress Med, 27 Taiping Rd, Beijing 100850, Peoples R China....Xu, XD;  Qimuge, AD;  Wang, HL;  Xing, C;  Gu, Y;  Liu, SS;  Xu, H;  Hu, MR;  Song, L;  Song, L (reprint author), Beijing Inst Basic Med Sci, Dept Stress Med, 27 Taiping Rd, Beijing 100850, Peoples R China.;  Song, L (reprint author), Anhui Med Univ, 81 Meishan Rd, Hefei 230032, Anhui, Peoples R China.;  Song, L (reprint author), Guangxi Med Univ, 22 Shuangyong Rd, Nanning 530021, Peoples R China.
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