兰州大学机构库

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Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 18, 页码: 824-832
Authors:  Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM...Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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antimicrobial peptides  intramolecular cyclization  click chemistry  stability  antimicrobial activity  secondary structure  mechanism of action  
Novel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 3, 页码: 690-702
Authors:  Xie, JQ;  Zhao, Q;  Li, SS;  Yan, ZB;  Li, J;  Li, Y;  Mou, LY;  Zhang, BZ;  Yang, WL;  Miao, XK...Xie, JQ;  Zhao, Q;  Li, SS;  Yan, ZB;  Li, J;  Li, Y;  Mou, LY;  Zhang, BZ;  Yang, WL;  Miao, XK;  Jiang, XX;  Wang, R;  Wang, R (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou, Guangdong, Peoples R China.
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analogs  antibiofilm  antimicrobial peptides  multidrug-resistant bacteria  stability  
Peripheral and central sites of action for anti-allodynic activity induced by the bifunctional opioid/NPFF receptors agonist BN-9 in inflammatory pain model 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2017, 卷号: 813, 期号: 2, 页码: 122-129
Authors:  Zhang, R;  Xu, B;  Zhang, MN;  Zhang, T;  Wang, ZL;  Zhao, G;  Zhao, GH;  Li, N;  Fang, Q;  Wang, R...Zhang, R;  Xu, B;  Zhang, MN;  Zhang, T;  Wang, ZL;  Zhao, G;  Zhao, GH;  Li, N;  Fang, Q;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, 199 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.
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BN-9  Opioid  Neuropeptide FF  Bifunctional agonist  Inflammatory pain  
MEL-N16: A Series of Novel Endomorphin Analogs with Good Analgesic Activity and a Favorable Side Effect Profile 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 17, 页码: 2180-2193
Authors:  Liu, X;  Zhao, L;  Wang, Y;  Zhou, JJ;  Wang, D;  Zhang, YX;  Zhang, XH;  Wang, ZJ;  Yang, DX;  Mou, LY...Liu, X;  Zhao, L;  Wang, Y;  Zhou, JJ;  Wang, D;  Zhang, YX;  Zhang, XH;  Wang, ZJ;  Yang, DX;  Mou, LY;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.
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antinociception  blood-brain barrier  endomorphin  side effect  stability  opioid peptide  
Nickel-Mediated Asymmetric Allylic Alkylation between Nitroallylic Acetates and Acyl Imidazoles 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 6, 页码: 4826-4829
Authors:  Wang, J;  Wang, PX;  Wang, LQ;  Li, D;  Wang, KZ;  Wang, Y;  Zhu, HY;  Yang, DX;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China....Wang, J;  Wang, PX;  Wang, LQ;  Li, D;  Wang, KZ;  Wang, Y;  Zhu, HY;  Yang, DX;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.
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Development of Biligands Magnesium Catalysis in Asymmetric Conjugate Reactions of C3-Pyrrolyl-Oxindoles 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 28, 页码: 4351-4354
Authors:  Wang, KZ;  Wang, LQ;  Liu, XH;  Li, D;  Zhu, HY;  Wang, PX;  Liu, YY;  Yang, DX;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China....Wang, KZ;  Wang, LQ;  Liu, XH;  Li, D;  Zhu, HY;  Wang, PX;  Liu, YY;  Yang, DX;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.
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Sulforaphane increases Nrf2 expression and protects alveolar epithelial cells against injury caused by cigarette smoke extract 期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 16, 期号: 4, 页码: 1241-1247
Authors:  Jiao, ZX;  Chang, JC;  Li, J;  Nie, DM;  Cui, HJ;  Guo, DF;  Jiao, ZX (reprint author), Lanzhou Univ, Sch Basic Med Sci, Res Inst Pathol, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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cigarette smoke extract  alveolar epithelial cells  sulforaphane  nuclear factor erythroid 2 like 2  
Intrahippocampal injection of Cortistatin-14 impairs recognition memory consolidation in mice through activation of sst(2), ghrelin and GABA(A/B) receptors 期刊论文
BRAIN RESEARCH, 2017, 卷号: 1666, 期号: 2, 页码: 38-47
Authors:  Jiang, JH;  Peng, YL;  He, Z;  Wei, LJ;  Jin, WD;  Wang, XL;  Chang, M;  Chang, M (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Life Sci, Inst Biochem & Mol Biol, Lanzhou 730000, Peoples R China.
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Cortistatin-14  Memory impairment  Hippocampus  SST receptors  Ghrelin receptor  GABA(A/B) receptors  
Endomorphin-1 analogs containing alpha-methyl-beta-amino acids exhibit potent analgesic activity after peripheral administration 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 12, 期号: 23, 页码: 4951-4955
Authors:  Wang, Y;  Yang, JX;  Liu, X;  Zhao, L;  Yang, DX;  Zhou, JJ;  Wang, D;  Mou, LY;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Dept Pharmacol, Inst Biochem & Mol Biol,Sch Basic Med Sci, Lanzhou 730000, Peoples R China....Wang, Y;  Yang, JX;  Liu, X;  Zhao, L;  Yang, DX;  Zhou, JJ;  Wang, D;  Mou, LY;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Dept Pharmacol, Inst Biochem & Mol Biol,Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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Magnesium Catalysis Mediated Tetrazoles in Desymmetrization Reaction of Aziridines 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 12, 页码: 3211-3214
Authors:  Li, D;  Wang, KZ;  Wang, LQ;  Wang, Y;  Wang, PX;  Liu, X;  Yang, DX;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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