兰州大学机构库
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Structure-constrained endomorphin analogs display differential antinociceptive mechanisms in mice after spinal administration 期刊论文
PEPTIDES, 2017, 卷号: 91, 页码: 40-48
Authors:  Wang, Y;  Zhou, JJ;  Liu, X;  Zhao, L;  Wang, ZJ;  Zhang, XH;  Wang, KZ;  Wang, LQ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China....Wang, Y;  Zhou, JJ;  Liu, X;  Zhao, L;  Wang, ZJ;  Zhang, XH;  Wang, KZ;  Wang, LQ;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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Spinal antinociception  Endomorphin  Dynorphin  Antagonist  Antibody  
Design of novel antimicrobial peptide dimer analogues with enhanced antimicrobial activity in vitro and in vivo by intermolecular triazole bridge strategy 期刊论文
PEPTIDES, 2017, 卷号: 88, 页码: 115-125
Authors:  Liu, BJ;  Huang, HF;  Yang, ZB;  Liu, BY;  Gou, SH;  Zhong, C;  Han, XF;  Zhang, Y;  Ni, JM;  Wang, R(王锐)...Liu, BJ;  Huang, HF;  Yang, ZB;  Liu, BY;  Gou, SH;  Zhong, C;  Han, XF;  Zhang, Y;  Ni, JM;  Wang, R(王锐);  Liu, BJ (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.;  Liu, BJ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Click chemistry  Dimer analogues  Antimicrobial activity  alpha Helical structure  Drug resistance  
Activation of NPFF2 receptor stimulates neurite outgrowth in Neuro 2A cells through activation of ERK signaling pathway 期刊论文
PEPTIDES, 2016, 卷号: 86, 页码: 24-32
Authors:  Yu, HP;  Zhang, N;  Zhang, T;  Wang, ZL;  Li, N;  Tang, HH;  Zhang, R;  Zhang, MN;  Xu, BA;  Fang, Q...Yu, HP;  Zhang, N;  Zhang, T;  Wang, ZL;  Li, N;  Tang, HH;  Zhang, R;  Zhang, MN;  Xu, BA;  Fang, Q;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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NPFF2 receptor  Neurite outgrowth  Neuro 2A cells  MEK/ERK signaling pathway  
Effects of the cannabinoid 1 receptor peptide ligands hemopressin, (m)RVD-hemopressin(alpha) and (m)VD-hemopressin(alpha) on memory in novel object and object location recognition tasks in normal young and Abeta1-42-treated mice. 期刊论文
NEUROBIOLOGY OF LEARNING AND MEMORY, 2016, 卷号: 134, 页码: 264-274
Authors:  Zhang, Rui-San;  He, Zhen;  Jin, Wei-Dong;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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Cannabinoid receptor  Hemopressin  (m)RVD-hemopressin(alpha)  (m)VD-hemopressin(alpha)  Recognition memory  Alzheimer's disease  
Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance 期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 108, 页码: 364-372
Authors:  Wang, ZL;  Li, N;  Wang, P;  Tang, HH;  Han, ZL;  Song, JJ;  Li, XH;  Yu, HP;  Zhang, T;  Zhang, R...Wang, ZL;  Li, N;  Wang, P;  Tang, HH;  Han, ZL;  Song, JJ;  Li, XH;  Yu, HP;  Zhang, T;  Zhang, R;  Xu, B;  Zhang, MN;  Fang, Q(方泉);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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Chimeric peptide  Endomorphin-2  Neuropeptide FF  Opioid  Antinociception  Non-tolerance  
Endomorphin-1 attenuates A beta(42) induced impairment of novel object and object location recognition tasks in mice 期刊论文
BRAIN RESEARCH, 2015, 卷号: 1629, 页码: 210-220
Authors:  Zhang, RS;  Xu, HJ;  Jiang, JH;  Han, RW;  Chang, M;  Peng, YL;  Wang, Y;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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Endomorphin-1  Amyloid-beta  Alzheimer's disease  Recognition memory  
Effects of neuropeptide FF and related peptides on the antinociceptive activities of VD-hemopressin(alpha) in naive and cannabinoid-tolerant mice 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 卷号: 767, 页码: 119-125
Authors:  Pan, JX;  Wang, ZL;  Li, N;  Zhang, N;  Wang, P;  Tang, HH;  Zhang, T;  Yu, HP;  Zhang, R;  Zheng, T...Pan, JX;  Wang, ZL;  Li, N;  Zhang, N;  Wang, P;  Tang, HH;  Zhang, T;  Yu, HP;  Zhang, R;  Zheng, T;  Fang, Q(方泉);  Wang, R(王锐);  Fang, Q (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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Cannabinoids  Neuropeptide FF  VD-hemopressin(alpha)  Antinociception  Tolerance  Mice  
Antimicrobial peptide protonectin disturbs the membrane integrity and induces ROS production in yeast cells 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2015, 卷号: 1848, 期号: 10, 页码: 2365-2373
Authors:  Wang, KR;  Dang, W;  Xie, JQ;  Zhu, RR;  Sun, MY;  Jia, FJ;  Zhao, YY;  An, XP;  Qiu, S;  Li, XY...Wang, KR;  Dang, W;  Xie, JQ;  Zhu, RR;  Sun, MY;  Jia, FJ;  Zhao, YY;  An, XP;  Qiu, S;  Li, XY;  Ma, ZL;  Yan, WJ;  Wang, R(王锐);  Yan, WJ (reprint author), Lanzhou Univ, Sch Basic Med Sci, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Protonectin  Antifungal  ROS production  Biofilm formation  
The improved blood-brain barrier permeability of endomorphin-1 using the cell-penetrating peptide synB3 with three different linkages 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2014, 卷号: 476, 期号: 1-2, 页码: 1-8
Authors:  Liu, H;  Zhang, W;  Ma, LN;  Fan, LL;  Gao, FY;  Ni, JM(倪京满);  Wang, R(王锐);  Ni, JM (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Life Sci,Sch Pharm, Key Lab Preclin Study New Drugs Gansu Prov, 222 South Tianshui Rd, Lanzhou 730000, Peoples R China.
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Endomorphin-1  Cell penetrating peptides  SynB3  Covalent linkage  Brain delivery  
The role of apelin-13 in novel object recognition memory 期刊论文
PEPTIDES, 2014, 卷号: 62, 页码: 155-158
Authors:  Han, RW;  Xu, HJ;  Zhang, RS;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Apelin-13  APJ  Object recognition  Short-term memory  Long-term memory