兰州大学机构库

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Druggable negative allosteric site of P2X3 receptors 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 19, 页码: 4939-4944
Authors:  Wang, J;  Wang, Y;  Cui, WW;  Huang, YC;  Yang, Y;  Liu, Y;  Zhao, WS;  Cheng, XY;  Sun, WS;  Cao, P...Wang, J;  Wang, Y;  Cui, WW;  Huang, YC;  Yang, Y;  Liu, Y;  Zhao, WS;  Cheng, XY;  Sun, WS;  Cao, P;  Zhu, MX;  Wang, R;  Hattori, M;  Yu, Y;  Hattori, M (reprint author), Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Sch Life Sci, Dept Physiol & Biophys,State Key Lab Genet Engn, Shanghai 200438, Peoples R China.;  Yu, Y (reprint author), Shanghai Jiao Tong Univ, Sch Med, Inst Med Sci, Dept Pharmacol & Chem Biol, Shanghai 200025, Peoples R China.;  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Gansu, Peoples R China.;  Yu, Y (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200025, Peoples R China.
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P2X3 receptors  allosteric inhibition  X-ray crystallography  AF-219  AF-353  
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 页码: 988-1002
Authors:  Liu, K;  Fang, LJ;  Sun, HY;  Pan, ZY;  Zhang, JC;  Chen, JT;  Shao, XM;  Wang, W;  Tan, YY;  Ding, ZH...Liu, K;  Fang, LJ;  Sun, HY;  Pan, ZY;  Zhang, JC;  Chen, JT;  Shao, XM;  Wang, W;  Tan, YY;  Ding, ZH;  Ao, LJ;  Wu, CL;  Liu, XQ;  Li, HS;  Wang, R;  Su, W;  Li, HC;  Li, HC (reprint author), Shenzhen Inst Adv Technol, 1068 Xueyuan Blvd, Shenzhen 518055, Guangdong, Peoples R China.;  Su, W (reprint author), Lanzhou Univ, 199 West Donggang Rd, Lanzhou 730020, Gansu, Peoples R China.
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Prolonged intervals during Mycobacterium tuberculosis subunit vaccine boosting contributes to eliciting immunity mediated by central memory-like T cells 期刊论文
TUBERCULOSIS, 2018, 卷号: 110, 期号: 5-6, 页码: 104-111
Authors:  Bai, CX;  He, JJ;  Niu, HX;  Hu, LN;  Luo, YP;  Liu, X;  Peng, L;  Zhu, BD;  Zhu, BD (reprint author), Lanzhou Univ, Inst Pathogen Biol, Sch Basic Med Sci, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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Mycobacterium tuberculosis  Subunit vaccine  Immunization schedules  Immune memory  Protective efficacy  
Tuberculosis vaccines: Opportunities and challenges 期刊论文
RESPIROLOGY, 2018, 卷号: 23, 期号: 6, 页码: 359-368
Authors:  Zhu, BD;  Dockrell, HM;  Ottenhoff, THM;  Evans, TG;  Zhang, Y;  Zhu, BD (reprint author), Lanzhou Univ, Lanzhou Ctr TB Res, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.;  Zhu, BD (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Pathogen Biol, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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biomarkers  clinical trials  immunity  tuberculosis  vaccines  
Histone Deacetylase 1 Inhibition Protects Against Hypoxia-Induced Swelling in H9c2 Cardiomyocytes Through Regulating Cell Stiffness 期刊论文
CIRCULATION JOURNAL, 2018, 卷号: 82, 期号: 10, 页码: 192
Authors:  Li, Y;  Zhang, ZY;  Zhou, XN;  Li, R;  Cheng, Y;  Shang, B;  Han, Y;  Liu, B;  Xie, XD;  Xie, XD (reprint author), Lanzhou Univ, Inst Med Genet, Sch Basic Med Sci, 222 Tianshuinan Rd, Lanzhou 730000, Gansu, Peoples R China....Li, Y;  Zhang, ZY;  Zhou, XN;  Li, R;  Cheng, Y;  Shang, B;  Han, Y;  Liu, B;  Xie, XD;  Xie, XD (reprint author), Lanzhou Univ, Inst Med Genet, Sch Basic Med Sci, 222 Tianshuinan Rd, Lanzhou 730000, Gansu, Peoples R China.;  Liu, B (reprint author), Lanzhou Univ, Sch Stomatol, 222 Tianshuinan Rd, Lanzhou 730000, Gansu, Peoples R China.
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Cardiomyocyte  Cellular swelling  Cobalt chloride (CoCl2)  Histone deacetylase 1 (HDAC1)  Stiffness  
Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 18, 页码: 824-832
Authors:  Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM...Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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antimicrobial peptides  intramolecular cyclization  click chemistry  stability  antimicrobial activity  secondary structure  mechanism of action  
Immunogenicity and protective efficacy of multistage vaccine candidates (Mtb8.4-HspX and HspX-Mtb8.4) against Mycobacterium tuberculosis infection in mice 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2017, 卷号: 53, 期号: 6, 页码: 83-89
Authors:  Liu, WB;  Li, JJ;  Niu, HX;  Lin, XF;  Li, RY;  Wang, Y;  Xin, Q;  Yu, HJ;  Wu, YM;  Zhu, BD...Liu, WB;  Li, JJ;  Niu, HX;  Lin, XF;  Li, RY;  Wang, Y;  Xin, Q;  Yu, HJ;  Wu, YM;  Zhu, BD;  Tan, JY;  Tan, JY (reprint author), Lanzhou Univ, Sch Basic Med Sci, Gansu Prov Key Lab Evidence Based Med, Lanzhou 7300004, Gansu, Peoples R China.;  Tan, JY (reprint author), Lanzhou Univ, Sch Basic Med Sci, Lanzhou Ctr TB Res, Lanzhou 7300004, Gansu, Peoples R China.;  Zhu, BD (reprint author), Lanzhou Univ, Inst Pathogen Biol, Sch Basic Med Sci, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.;  Tan, JY (reprint author), Sch Basic Med Sci, Immunol, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.;  Tan, JY (reprint author), Sch Basic Med Sci, Gansu Prov Key Lab Evidence Based Med & Clin Tran, 199 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.
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Mycobacterium tuberculosis  Protein vaccine  Mtb8.4  HspX  Protein sequential order  Antigen dose  
A Genetic Variant in a Homocysteine Metabolic Gene that Increases the Risk of Congenital Cardiac Septal Defects in Han Chinese Populations 期刊论文
IUBMB LIFE, 2017, 卷号: 69, 期号: 28, 页码: 700-705
Authors:  Xie, HH;  Li, J;  Li, PQ;  Zhang, AA;  Li, Y;  Wang, YZ;  Xie, DX;  Xie, XD;  Xie, DX (reprint author), Gansu Cardiovasc Inst, Lanzhou 730050, Gansu, Peoples R China.;  Xie, XD (reprint author), Lanzhou Univ, Sch Basic Med Sci, Lanzhou 730000, Gansu, Peoples R China....Xie, HH;  Li, J;  Li, PQ;  Zhang, AA;  Li, Y;  Wang, YZ;  Xie, DX;  Xie, XD;  Xie, DX (reprint author), Gansu Cardiovasc Inst, Lanzhou 730050, Gansu, Peoples R China.;  Xie, XD (reprint author), Lanzhou Univ, Sch Basic Med Sci, Lanzhou 730000, Gansu, Peoples R China.
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congenital cardiac septal defects  single nucleotidepolymorphisms  homocysteine  SYT9  
Subunit Vaccines Consisting of Antigens from Dormant and Replicating Bacteria Show Promising Therapeutic Effect against Mycobacterium Bovis BCG Latent Infection 期刊论文
SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2017, 卷号: 85, 期号: 6, 页码: 425-432
Authors:  Li, F;  Kang, H;  Li, J;  Zhang, D;  Zhang, Y;  Dannenberg, AM;  Liu, X;  Niu, H;  Ma, L;  Tang, R...Li, F;  Kang, H;  Li, J;  Zhang, D;  Zhang, Y;  Dannenberg, AM;  Liu, X;  Niu, H;  Ma, L;  Tang, R;  Han, X;  Gan, C;  Ma, X;  Tan, J;  Zhu, B;  Zhu, B (reprint author), Lanzhou Univ, Inst Pathogen Biol, Sch Basic Med Sci, 199 West Donggang Rd, Lanzhou 730000, Peoples R China.
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A New Rabbit-Skin Model to Evaluate Protective Efficacy of Tuberculosis Vaccines 期刊论文
FRONTIERS IN MICROBIOLOGY, 2017, 卷号: 8
Authors:  Chen, HY;  Liu, X;  Ma, XM;  Wang, Q;  Yang, G;  Niu, HX;  Li, SX;  He, BZ;  He, SS;  Dannenberg, AM...Chen, HY;  Liu, X;  Ma, XM;  Wang, Q;  Yang, G;  Niu, HX;  Li, SX;  He, BZ;  He, SS;  Dannenberg, AM;  Zhu, BD;  Zhang, Y;  Zhu, BD (reprint author), Lanzhou Univ, Gansu Key Lab Evidence Based Med & Clin Transfer, Lanzhou, Peoples R China.;  Zhu, BD (reprint author), Lanzhou Univ, Lanzhou Ctr TB Res, Lanzhou, Peoples R China.;  Zhu, BD (reprint author), Lanzhou Univ, Inst Pathogen Biol, Sch Basic Med Sci, Lanzhou, Peoples R China.;  Zhang, Y (reprint author), Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD USA.
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tuberculosis  subunit vaccine  BCG  rabbit skin model  pathology