兰州大学机构库

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Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 18, 页码: 824-832
Authors:  Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM...Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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antimicrobial peptides  intramolecular cyclization  click chemistry  stability  antimicrobial activity  secondary structure  mechanism of action  
Design of novel antimicrobial peptide dimer analogues with enhanced antimicrobial activity in vitro and in vivo by intermolecular triazole bridge strategy 期刊论文
PEPTIDES, 2017, 卷号: 88, 页码: 115-125
Authors:  Liu, BJ;  Huang, HF;  Yang, ZB;  Liu, BY;  Gou, SH;  Zhong, C;  Han, XF;  Zhang, Y;  Ni, JM;  Wang, R(王锐)...Liu, BJ;  Huang, HF;  Yang, ZB;  Liu, BY;  Gou, SH;  Zhong, C;  Han, XF;  Zhang, Y;  Ni, JM;  Wang, R(王锐);  Liu, BJ (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.;  Liu, BJ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Click chemistry  Dimer analogues  Antimicrobial activity  alpha Helical structure  Drug resistance  
Catalytic Desymmetrization of meso-Aziridines with Benzofuran-2(3H)-Ones Employing a Simple In Situ-Generated Magnesium Catalyst 期刊论文
ACS CATALYSIS, 2015, 卷号: 5, 期号: 12, 页码: 7432-7436
Authors:  Li, D;  Wang, LQ;  Yang, DX;  Zhang, BZ(张邦治);  Wang, R(王锐);  Zhang, BZ (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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desymmetrization  meso-aziridines  benzofuran-2(3H)-ones  magnesium catalyst  BINOL  
Catalytic Asymmetric Michael Reaction of 5H-Oxazol-4-Ones with alpha,beta-Unsaturated Acyl Imidazoles 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2015, 卷号: 21, 期号: 48, 页码: 17234-17238
Authors:  Zhang, BZ(张邦治);  Han, FX;  Wang, LQ;  Li, D;  Yang, DX;  Yang, XL;  Yang, JX;  Li, XF;  Zhao, DP;  Wang, R(王锐)...Zhang, BZ(张邦治);  Han, FX;  Wang, LQ;  Li, D;  Yang, DX;  Yang, XL;  Yang, JX;  Li, XF;  Zhao, DP;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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asymmetric synthesis  heterocycles  ligand design  Michael addition  zinc  
Catalytic Asymmetric [3+2] Cyclization Reactions of 3-lsothiocyanato Oxindoles and Alkynyl Ketones Via an in Situ Generated Magnesium Catalyst 期刊论文
ORGANIC LETTERS, 2015, 卷号: 17, 期号: 17, 页码: 4260-4263
Authors:  Wang, LQ;  Yang, DX;  Li, D;  Liu, XH;  Zhao, Q;  Zhu, RR;  Zhang, BZ(张邦治);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Sch Life Sci, Lanzhou 730000, Peoples R China.
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Application of a C-C Bond-Forming Conjugate Addition Reaction in Asymmetric Dearomatization of beta-Naphthols 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 33, 页码: 9523-9527
Authors:  Yang, DX;  Wang, LQ;  Kai, M;  Li, D;  Yao, XJ(姚小军);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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arenes  aromaticity  DFT calculations  magnesium  naphthols  
Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria 会议论文
JOURNAL OF PEPTIDE SCIENCE, Datong City, PEOPLES R CHINA, JUN 30-JUL 04, 2014
Authors:  Xie, JQ;  Gou, YM;  Zhao, Q;  Li, SS;  Zhang, W;  Song, JJ;  Mou, LY;  Li, JY;  Wang, KR;  Zhang, BZ...Xie, JQ;  Gou, YM;  Zhao, Q;  Li, SS;  Zhang, W;  Song, JJ;  Mou, LY;  Li, JY;  Wang, KR;  Zhang, BZ;  Yang, WL;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Multidrug-resistant Bacteria  Cell-penetrating Peptides  Transportan 10  Structure-activity Relationships  Action Mechanism  
Catalytic Enantioselective Ring-Opening and Ring-Closing Reactions of 3-Isothiocyanato Oxindoles and N-(2-Picolinoyl)aziridines 期刊论文
ORGANIC LETTERS, 2015, 卷号: 17, 期号: 12, 页码: 3004-3007
Authors:  Wang, LQ;  Yang, DX;  Li, D;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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Development and Application of alpha-Heteroatom Ketones in Asymmetric Michael Reaction with beta-trans-Nitroalkenes 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2015, 卷号: 80, 期号: 9, 页码: 4336-4348
Authors:  Yang, DX;  Li, D;  Wang, LQ;  Zhao, DP;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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Intermolecular Enantioselective Dearomatization Reaction of beta-Naphthol Using meso-Aziridine: A Bifunctional In Situ Generated Magnesium Catalyst 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 7, 页码: 2185-2189
Authors:  Yang, DX;  Wang, LQ;  Han, FX;  Li, D;  Zhao, DP;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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arenes  aromaticity  intermolecular reactions  ligand design  magnesium