兰州大学机构库

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Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 18, 页码: 824-832
Authors:  Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM...Liu, BJ;  Zhang, W;  Gou, SH;  Huang, HF;  Yao, J;  Yang, ZB;  Liu, H;  Zhong, C;  Liu, BY;  Ni, JM;  Wang, R;  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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antimicrobial peptides  intramolecular cyclization  click chemistry  stability  antimicrobial activity  secondary structure  mechanism of action  
Design of novel antimicrobial peptide dimer analogues with enhanced antimicrobial activity in vitro and in vivo by intermolecular triazole bridge strategy 期刊论文
PEPTIDES, 2017, 卷号: 88, 页码: 115-125
Authors:  Liu, BJ;  Huang, HF;  Yang, ZB;  Liu, BY;  Gou, SH;  Zhong, C;  Han, XF;  Zhang, Y;  Ni, JM;  Wang, R(王锐)...Liu, BJ;  Huang, HF;  Yang, ZB;  Liu, BY;  Gou, SH;  Zhong, C;  Han, XF;  Zhang, Y;  Ni, JM;  Wang, R(王锐);  Liu, BJ (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.;  Liu, BJ (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
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Click chemistry  Dimer analogues  Antimicrobial activity  alpha Helical structure  Drug resistance  
BN-9, a chimeric peptide with mixed opioid and neuropeptide FF receptor agonistic properties, produces nontolerance-forming antinociception in mice 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2016, 卷号: 173, 期号: 11, 页码: 1864-1880
Authors:  Li, N;  Han, ZL;  Wang, ZL;  Xing, YH;  Sun, YL;  Li, XH;  Song, JJ;  Zhang, T;  Zhang, R;  Zhang, MN...Li, N;  Han, ZL;  Wang, ZL;  Xing, YH;  Sun, YL;  Li, XH;  Song, JJ;  Zhang, T;  Zhang, R;  Zhang, MN;  Xu, BA;  Fang, Q(方泉);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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Catalytic Desymmetrization of meso-Aziridines with Benzofuran-2(3H)-Ones Employing a Simple In Situ-Generated Magnesium Catalyst 期刊论文
ACS CATALYSIS, 2015, 卷号: 5, 期号: 12, 页码: 7432-7436
Authors:  Li, D;  Wang, LQ;  Yang, DX;  Zhang, BZ(张邦治);  Wang, R(王锐);  Zhang, BZ (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
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desymmetrization  meso-aziridines  benzofuran-2(3H)-ones  magnesium catalyst  BINOL  
Catalytic Asymmetric Michael Reaction of 5H-Oxazol-4-Ones with alpha,beta-Unsaturated Acyl Imidazoles 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2015, 卷号: 21, 期号: 48, 页码: 17234-17238
Authors:  Zhang, BZ(张邦治);  Han, FX;  Wang, LQ;  Li, D;  Yang, DX;  Yang, XL;  Yang, JX;  Li, XF;  Zhao, DP;  Wang, R(王锐)...Zhang, BZ(张邦治);  Han, FX;  Wang, LQ;  Li, D;  Yang, DX;  Yang, XL;  Yang, JX;  Li, XF;  Zhao, DP;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Sch Life Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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asymmetric synthesis  heterocycles  ligand design  Michael addition  zinc  
Neuropeptide VF Enhances Cannabinoid Agonist WIN55,212-2-Induced Antinociception in Mice 期刊论文
ANESTHESIA AND ANALGESIA, 2015, 卷号: 121, 期号: 5, 页码: 1360-1368
Authors:  Han, ZL;  Wang, ZL;  Li, XH;  Li, N;  Pan, JX;  Zheng, T;  Fang, Q(方泉);  Wang, R(王锐);  Fang, Q (reprint author), Lanzhou Univ, Sch Basic Med Sci, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
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Antimicrobial peptide protonectin disturbs the membrane integrity and induces ROS production in yeast cells 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2015, 卷号: 1848, 期号: 10, 页码: 2365-2373
Authors:  Wang, KR;  Dang, W;  Xie, JQ;  Zhu, RR;  Sun, MY;  Jia, FJ;  Zhao, YY;  An, XP;  Qiu, S;  Li, XY...Wang, KR;  Dang, W;  Xie, JQ;  Zhu, RR;  Sun, MY;  Jia, FJ;  Zhao, YY;  An, XP;  Qiu, S;  Li, XY;  Ma, ZL;  Yan, WJ;  Wang, R(王锐);  Yan, WJ (reprint author), Lanzhou Univ, Sch Basic Med Sci, 222 Tian Shui South Rd, Lanzhou 730000, Peoples R China.
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Protonectin  Antifungal  ROS production  Biofilm formation  
Catalytic Asymmetric [3+2] Cyclization Reactions of 3-lsothiocyanato Oxindoles and Alkynyl Ketones Via an in Situ Generated Magnesium Catalyst 期刊论文
ORGANIC LETTERS, 2015, 卷号: 17, 期号: 17, 页码: 4260-4263
Authors:  Wang, LQ;  Yang, DX;  Li, D;  Liu, XH;  Zhao, Q;  Zhu, RR;  Zhang, BZ(张邦治);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Sch Life Sci, Lanzhou 730000, Peoples R China.
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Application of a C-C Bond-Forming Conjugate Addition Reaction in Asymmetric Dearomatization of beta-Naphthols 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 33, 页码: 9523-9527
Authors:  Yang, DX;  Wang, LQ;  Kai, M;  Li, D;  Yao, XJ(姚小军);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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arenes  aromaticity  DFT calculations  magnesium  naphthols  
Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes 期刊论文
ORGANIC LETTERS, 2015, 卷号: 17, 期号: 15, 页码: 3826-3829
Authors:  Zhu, YY;  Li, XY;  Chen, Q;  Su, JH;  Jia, FJ;  Qiu, S;  Ma, MX;  Sun, QT;  Yan, WJ;  Wang, KR...Zhu, YY;  Li, XY;  Chen, Q;  Su, JH;  Jia, FJ;  Qiu, S;  Ma, MX;  Sun, QT;  Yan, WJ;  Wang, KR;  Wang, R(王锐);  Yan, WJ (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Pharmacol, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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