个人详细信息
王少华

王少华

副教授
兰州大学 药学院
王少华,男,副教授,硕士研究生导师,目前主要从事天然活性药物分子及其衍生物的全合成、药物合成方法学、新的药物筛选方法开发等研究。开展了中国传统中药中的活性分子的全合成研究,已合作完成了七个含季碳中心的活性天然产物分子的全合成;同时,开展了构筑常见药用分子骨架的方法学研究。发表SCI论文40余篇,其中SCI一区论文4篇,SCI二区论文20余篇,以第一作者参编国际专著一章。
个人详细信息

研究成果

52 3539 22 17
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[1] Xu, MH,Tu, YQ,Tian, JM,et al. Asymmetric Epoxidation Of Alpha,beta-unsaturated Aldehydes Catalyzed By A Spiro-pyrrolidine-derived Organocatalyst[J]. Tetrahedron-asymmetry,2016,27(6):294-300.
浏览/下载:66/0
[2] Hou, SH,Tu, YQ,Wang, SH,et al. Total Syntheses Of The Tetracyclic Cyclopiane Diterpenes Conidiogenone, Conidiogenol, And Conidiogenoneb[J]. Angewandte Chemie-international Edition,2016,55(14):4456-4460.
浏览/下载:72/0
[3] Dou, QY,Tu, YQ,Zhang, Y,et al. Spiro-pyrrolidine-catalyzed Asymmetric Conjugate Addition Of Hydroxylamine To Enals And 2,4-dienals[J]. Advanced Synthesis & Catalysis,2016,358(6):874-879.
浏览/下载:115/0
[4] Liu, WX,Chen, SK,Tian, JM,et al. A Triazole Organocatalyst With Spiropyrrolidine Framework And Its Application To The Catalytic Asymmetric Addition Of Nitromethane To Alpha,beta-unsaturated Aldehydes[J]. Advanced Synthesis & Catalysis,2015,357(18):3831-3835.
浏览/下载:50/0
[5] Zhu, DY,Xu, MH,Tu, YQ,et al. Catalytic Asymmetric Construction Of -quaternary Cyclopentanones And Its Application To The Syntheses Of (-)-1,14-herbertenediol And (-)-aphanorphine[J]. Chemistry-a European Journal,2015,21(44):15502-15505.
浏览/下载:82/0
[6] Yang, BM,Cai, PJ,Tu, YQ,et al. Organocatalytic Asymmetric Tandem Nazarov Cyclization/semipinacol Rearrangement: Rapid Construction Of Chiral Spiro[4.4]nonane-1,6-diones[J]. Journal Of The American Chemical Society,2015,137(26):8344-8347.
浏览/下载:100/0
[7] Jiao, ZW,Tu, YQ,Zhang, Q,et al. Tandem C-h Oxidation/cyclization/rearrangement And Its Application To Asymmetric Syntheses Of (-)-brussonol And (-)-przewalskine E[J]. Nature Communications,2015,6.
浏览/下载:90/0
[8] Zhu, DY,Zhang, Z,Mou, XQ,et al. Gold(i)/copper(ii)-cocatalyzed Tandem Cyclization/semipinacol Reaction: Construction Of 6-aza/oxa-spiro[4.5]decane Skeletons And Formal Synthesis Of (+/-)-halichlorine[J]. Advanced Synthesis & Catalysis,2015,357(4):747-752.
浏览/下载:79/0
[9] Tian, JM,Yuan, YH,Tu, YQ,et al. The Design Of A Spiro-pyrrolidine Organocatalyst And Its Application To Catalytic Asymmetric Michael Addition For The Construction Of All-carbon Quaternary Centers[J]. Chemical Communications,2015,51(49):9979-9982.
浏览/下载:33/0
[10] Mou, XQ,Xu, ZL,Xu, L,et al. The Synthesis Of Multisubstituted Pyrroles Via A Copper-catalyzed Tandem Three-component Reaction[J]. Organic Letters,2016,18(16):4032-4035.
浏览/下载:39/0
总共6页 当前第1页 1

研究主题

copper[3] semipinacol rearrangement[3] asymmetric catalysis[3] fluorine[2] natural products[2] organocatalysis[2] rearrangement[2] alkaloids[2] Michael addition[2] Didemnaketal A[2] total synthesis[2] 三氟甲基[1] β-环氧醇[1] 全氟烷基[1] 手性联萘酚[1]

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