兰州大学机构库 >化学化工学院
Solid-Phase Synthesis of Highly Fluorescent Nitrogen-Doped Carbon Dots for Sensitive and Selective Probing Ferric Ions in Living Cells
Zhang, HJ; Chen, YL(陈永雷); Liang, MJ; Xu, LF; Qi, SD(齐升达); Chen, HL(陈宏丽); Chen, XG(陈兴国); Chen, XG (reprint author), Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
ESI NOTE2017-07-19;Highly Cited Papers
2014-10-06
Source PublicationANALYTICAL CHEMISTRY
ISSN0003-2700
Volume86Issue:19Pages:9846-9852
AbstractCarbon quantum dots (C-Dots) have drawn extensive attention in recent years due to their stable physicochemical and photochemical properties. However, the development of nitrogen-doped carbon quantum dots (N-doped C-Dots) is still on its early stage. In this paper, a facile and high-output solid-phase synthesis approach was proposed for the fabrication of N-doped, highly fluorescent carbon quantum dots. The obtained N-doped C-Dots exhibited a strong blue emission with an absolute quantum yield (QY) of up to 31%, owing to fluorescence enhancement effect of introduced N atoms into carbon dots. The strong coordination of oxygen-rich groups on N-doped C-Dots to Fe3+ caused fluorescence quenching via nonradiative electron-transfer, leading to the quantitative detection of Fe3+. The probe exhibited a wide linear response concentration range (0.01-500 mu M) to Fe3+ with a detection limit of 2.5 nM. Significantly, the N-doped C-Dots possess negligible cytotoxicity, excellent biocompatibility, and high photostability. All these features are favorable for label-free monitoring of Fe3+ in complex biological samples. It was then successfully applied for the fluorescence imaging of intracellular Fe3+. As an efficient chemosensor, the N-doped C-Dots hold great promise to broaden applications in biological systems.
Subject AreaChemistry
PublisherAMER CHEMICAL SOC
DOI10.1021/ac502446m
Publication PlaceWASHINGTON
Indexed BySCIE ; EI ; PubMed ; MEDLINE ; ESI
Language英语
First Inst
Funding Project国家自然科学基金项目 ; 高等学校博士学科点专项科研基金
Project NumberNational Natural Science Foundation of China [21375053] ; Special Doctorial Program Fund from the Ministry of Education of China [20130211110039]
WOS IDWOS:000343017100072
Funding OrganizationNSFC ; MOE
SubtypeArticle
EI ID20144300120619
PMID 25211236
Department
[Zhang, Haijuan;
Chen, Yonglei;
Liang, Meijuan;
Xu, Laifang;
Qi, Shengda;
Chen, Hongli;
Chen, Xingguo] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China;
[Zhang, Haijuan;
Chen, Yonglei;
Liang, Meijuan...更多
Citation statistics
Cited Times:370[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/103274
Collection化学化工学院
Corresponding AuthorChen, XG (reprint author), Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
Recommended Citation
GB/T 7714
Zhang, HJ,Chen, YL,Liang, MJ,et al. Solid-Phase Synthesis of Highly Fluorescent Nitrogen-Doped Carbon Dots for Sensitive and Selective Probing Ferric Ions in Living Cells[J]. ANALYTICAL CHEMISTRY,2014,86(19):9846-9852.
APA Zhang, HJ.,Chen, YL.,Liang, MJ.,Xu, LF.,Qi, SD.,...&Chen, XG .(2014).Solid-Phase Synthesis of Highly Fluorescent Nitrogen-Doped Carbon Dots for Sensitive and Selective Probing Ferric Ions in Living Cells.ANALYTICAL CHEMISTRY,86(19),9846-9852.
MLA Zhang, HJ,et al."Solid-Phase Synthesis of Highly Fluorescent Nitrogen-Doped Carbon Dots for Sensitive and Selective Probing Ferric Ions in Living Cells".ANALYTICAL CHEMISTRY 86.19(2014):9846-9852.
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