兰州大学机构库 >口腔医学院
Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane
Ma HaiBin1,3; Su WenXin2; Tai ZhiXin1; Sun DongFei1; Yan XingBin1; Liu Bin2; Xue QunJi1
2012-08
Source PublicationCHINESE SCI BULL   Impact Factor & Quartile Of Published Year  The Latest Impact Factor & Quartile
ISSN1001-6538
Volume57Issue:23Pages:3051-3058
AbstractA series of polylactic acid (PLA) based nanocomposite fibrous membranes, including neat PLA, PLA/hydroxyapatite (HA) and PLA/HA/graphene oxide (GO), were fabricated via electrospinning method. The morphology and composition were investigated by scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) respectively. The thermal stability was determined by thermogravimetric analysis (TGA). To estimate the cytocompatibility of asprepared PLA/HA/GO fibrous membrane, MC3T3-E1 cells were cultured, and the corresponding cell adhesion and differentiation capability were investigated by fluorescence microscopy, SEM and MTT test. The electrospun ternary PLA/HA/GO membrane exhibited three-dimensional fibrous structure with relatively rough surface morphology, which made itself ideal for cell attachment and proliferation in bone tissue regeneration. The fluorescence microscopy, SEM and MTT test confirmed that the PLA/HA/GO nanocomposite fibrous membrane created a proper environment for the seeding and proliferation of MC3T3-E1 cells.
Keywordpolylactic acid hydroxyapatite graphene oxide fibrous membranes
Subject AreaScience & Technology - Other Topics
PublisherSCIENCE CHINA PRESS
DOI10.1007/s11434-012-5336-3
Publication PlaceBEIJING
Indexed BySCIE
Language英语
First Inst
Funding Project国家自然科学基金项目
Host of Journal中国科学院
Project NumberHundred Talents Program of Chinese Academy of Sciences ; National Natural Science Foundation of China [51005225]
WOS IDWOS:000307277800015
Funding OrganizationNSFC
SubtypeArticle
Department[Ma HaiBin;
Tai ZhiXin;
Sun DongFei;
Yan XingBin;
Xue QunJi] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China;
[Su WenXin;
Liu Bin] Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China;
[Ma HaiBin] Gansu Prov Hosp Tradit Chinese Med, Lanzhou 730050, Peoples R China
Citation statistics
Document Type期刊论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/122096
Collection口腔医学院
Corresponding AuthorYan XingBin
Affiliation
1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China
2.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China
3.Gansu Prov Hosp Tradit Chinese Med, Lanzhou 730050, Peoples R China
Recommended Citation
GB/T 7714
Ma HaiBin,Su WenXin,Tai ZhiXin,et al. Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane[J]. CHINESE SCI BULL,2012,57(23):3051-3058.
APA Ma HaiBin.,Su WenXin.,Tai ZhiXin.,Sun DongFei.,Yan XingBin.,...&Xue QunJi.(2012).Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane.CHINESE SCI BULL,57(23),3051-3058.
MLA Ma HaiBin,et al."Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane".CHINESE SCI BULL 57.23(2012):3051-3058.
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