兰州大学机构库 >学院待认领
重症下肢缺血性疾病的腔内治疗
Alternative TitleExperience of Endovascular Treatment of Critical Limb Ischemia
杨川
Thesis Advisor周栋
2015-05-20
Degree Grantor兰州大学
Place of Conferral兰州
Degree Name硕士
Keyword重症下肢缺血 腔内治疗 经皮腔内血管成形术 球囊扩张 支架植入
Abstract目的 探讨与分析重症下肢缺血的腔内治疗效果及其临床价值,提高下肢重症缺血性疾病的治疗成功率。 方法 回顾性分析兰大二院血管外科2011年9月~2014年9月住院的确诊为重症下肢缺血并行血管腔内治疗的患者32例共35条患肢的详细临床资料和相关随访资料。评估分析术前术后临床症状改善、ABI值变化及CTA影像学改变,观察术后即时效果、住院期间临床疗效、有无并发症、ABI值的变化。随访6~24个月,观察血管再通情况及患者下肢缺血症状改善状况。 结果 髂动脉的开通率及支架植入的成功率为100%,股腘动脉的球囊扩张及支架植入的成功率为100%,膝下动脉的球囊扩张成功率为81.2%。术后患者症状改善,患者即感下肢皮温增高,静息痛缓解或消失,溃疡逐渐愈合。围手术期截肢3例,截肢率为8.9%。患者术后平均ABI为0.70 ,与术前相比有显著性差异(P<0.05)。随访期间死亡率7.1%,截肢率3.5%,溃疡复发率7.1%,再狭窄率21.4%。结论 血管腔内技术是治疗重症下肢缺血安全有效的方式。由于该疾病仍具有较高的致残率,依然需要进一步研究。
Other AbstractMethods Clinical data and follow-up data of 32 patients(35 limbs) with critical limb ischemia treated by endovascular treatment in department of vascular surgery of Lanzhou university second hospital from September 2011~September 2013 were analyzed and summarized. Analysis and assess the clinical symptoms before and after surgery, the changes of ABI and the effects of CTA. Observed immediate effects after surgery, clinical efficacy during hospitalization, complications, changes of ABI. The situation of recanalization and ischemic symptoms of lower limb of patients was observed in the follow-up of 6~24 months. Results The success rate of endovascular procedure was 100% for iliac arteries and femoral-popliteal arteries,and 81.2% for infrapopliteal artery. Temperature of lower limb skin increased ,rest pain eased or disappeared and the ulcers were healed after the operations.1 patient received amputation during the perioperative period ,the rate of amputation was 8.9%. Compared with the preoperative , there was a significant difference (P<0.05) for the average of ABI patients was 0.70. Mortality of patients endovascular intervened is 7.1%, the amputation rate is 3.5%,recurrence rate of ulcer is 7.1% and restenosis rate is 21.4%. Conclusion Endovascular technique is safe and effective in the treatment of critical limb ischemia. CLI still need further study cause it has a high morbidity.
URL查看原文
Language中文
Document Type学位论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/222184
Collection学院待认领
Affiliation临床医学院
Recommended Citation
GB/T 7714
杨川. 重症下肢缺血性疾病的腔内治疗[D]. 兰州. 兰州大学,2015.
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