兰州大学机构库 >学院待认领
机械与手工食管胃吻合术后吻合口瘘发生率比较的系统评价
Alternative TitleHand-Suture versus Stapling Anastomosis in the Incidence of Anastomotic Leakage Following Esophagogastrostomy:A Systematic Review
张雪飞
Thesis Advisor韩彪
2013-05-29
Degree Grantor兰州大学
Place of Conferral兰州
Degree Name硕士
Keyword食管胃吻合术 吻合口瘘 机械吻合 手工吻合 Meta分析 系统评价 随机对照试验
Abstract目的 系统评价机械与手工食管胃吻合术后吻合口瘘发生率。方法 计算机检索CBM(1978-2012.2)、VIP(1989-2012.2)、CNKI(1994- 2012.2)、WanFang Data(1980-2012.2)、The Cochrane Library、Pubmed( 1966-2012.2)、EMbase(1974-2012.2)以及相关临床试验网站,查找比较机械与手工食管胃吻合术后患者吻合口瘘发生率的随机和半随机对照试验。并运用Google Scholar、Medical Martix 等搜索引擎,查找相关参考文献及灰色文献;手工检索《中华肿瘤学》等相关中文期刊。按照纳入和排除标准筛选文献、提取资料并评价纳入研究的方法学质量后,并用RevMan 5.0软件进行Meta分析。结果 最终纳入9篇RCT,2202例患者,Meta分析结果显示:机械吻合术后患者吻合口瘘的发生率低于手工吻合[OR=0.43,95%CI(0.26-0.71,P<0.01]。结论 机械吻合在降低食管胃吻合术后患者吻合口发生瘘方面优于手工吻合。受纳入研究质量和数量限制,上述结论尚需开展更多高质量研究加以验证。
Other AbstractObjective To assess the effectiveness and safety of hand-suture vs stapling anastomosis in esophagogastrostomy. Methods The following databases such as CBM(1978-2012.2), VIP(1989-2012.2), CNKI(1994- 2012.2),WanFang Data(1980-2012.2), The Cochrane Library,Pubmed ( 1966-2012.2), EMbase(1974-2012.2),and relevant webs of clinical trials were searched to collect the randomized controlled trials(RCTs) and quasi-RCTs about hand-suture vs stapling anastomosis in the incidence of anastomotic leakage following esophagogastrostomy.Moreover,relevant references and grey literature were retrieved on web engines including Google Scholar and Medical Martix,and the Chinese periodicals eg Chinese Journal of onclolgy were also hand-searched. According to the inclusion and exclusion criteria,the literature,was screened,the data were extracted,and the quality of the included studies was assessed.Then meta-analysis was conducted using RevMan 5.0 software. Results A total of 9 RCTs involving 2202 patients were included. The result of meta-analysis were as follows:the incidence of anastomotic leakage in the stapling anastomosis group was lower than that in the hand-suture anastomosis group (OR=0.43,95%CI,0.26-0.71,P<0.01). Conclusion Stapling anastomosis is superior to hand-suture anastomosis in reducing the incidence of anastomotic leakage following esophagogastrostomy.For the limited quality and quantity of the included studies,this conclusion has to be further proved by more high-quality studies.
URL查看原文
Language中文
Document Type学位论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/223287
Collection学院待认领
Affiliation临床医学院
Recommended Citation
GB/T 7714
张雪飞. 机械与手工食管胃吻合术后吻合口瘘发生率比较的系统评价[D]. 兰州. 兰州大学,2013.
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