| 冠心病危险因素对PCI治疗预后的影响 |
| Alternative Title | Influence of the risk factors of coronary heart disease on the prognosis of percutaneous coronary interventions
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| 陈曼丽 |
| Thesis Advisor | 张钲
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| 2010-05-12
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| Degree Grantor | 兰州大学
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| Place of Conferral | 兰州
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| Degree Name | 硕士
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| Keyword | 冠心病
危险因素
PCI治疗
预后
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| Abstract | 目的：探讨冠心病危险因素对经皮冠状动脉介入术(percutaneous coronary intervention,PCI) 治疗预后的影响。
方法：回顾性分析2007年1月至2008年7月在兰州大学第一医院确诊为冠心病且行PCI治疗的住院患者的冠心病危险因素。随访观察术后12个月内发生主要不良心脏事件的情况，分析其与冠心病危险因素的相关性。
结果：入选的446例患者,年龄32～80岁，平均年龄60.23±9.75岁；男性84.97%（379/446），有冠心病家族史者2.24%（10/446）；合并糖尿病者20.63%（92/446）；合并高血压病者52.26％（242/446）；血脂异常者42.15%（118/446）；超重者62.33%（278/446）；吸烟者57.85％（258/446）。随访12个月内MACE发生率5.83%。经 分析：女性、冠心病家族史、超重、高血压及吸烟患者在PCI术后12个月内MACE的发生分别与无以上危险因素的患者人群相比，差异均有统计学意义( 值分别为4.133、6.848、3.997、3.939、4.120，P均<0.05)。Logistic回归分析结果示MACE与家族史、超重、性别相关（OR值分别为7.383、10.504、0.058，P均<0.05）。
结论：冠心病患者接受PCI治疗总体预后良好。PCI术后，冠心病危险因素（吸烟、高血压、超重等）仍需加以控制，以减少MACE的发生。 |
| Other Abstract | Objective:To assess the influence of risk factors of coronary heart disease (CHD) on the prognosis of percutaneous coronary interventions(PCI).
Methods:Retrospective analyze the cardiovascular risk factors in patients,who admitted to the First Hospital of Lanzhou University and received PCI treatment from January 2007 to July 2008.And analyze the relationship between cardiovascular risks and the major adverse cardiac event (MACE) in the 12-month follow-up.
Results:The mean age of all 446 CHD patients was 60.23 ± 9.75 years.Among all the patients,84.97%(379/446) was male,2.24%(10/446) had family history of CHD, 20.63%(92/446) was complicated with diabetes,52.26% (242/446) with hypertension,42.15% (118/446) with dyslipidemia,62.33%(278/446) of the patients was overweight,57.85%(258/446) was smoker.Within 12 months of follow-up,MACE incidence rate were 5.83%.The MACE incidence rate of various risk factors group including female,family history,overweight,hypertension and smoking were significantly different with the no risk group (X2=4.133,6.848,3.997,3.939,4.120，P<0.05).Logistic regression analysis showed family history and overweight increased the risk of MACE（OR=7.383 and 10.504,P <0.05）,being male protected against MACE(OR=0.058,P <0.05).
Conclusion: The patients accepted PCI showed well prognosis. After PCI, the risk factors of CHD such as smoking,hypertension,overweight,etcshould be under control to decrease the occurrence of MACE. |
| URL | 查看原文
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| Language | 中文
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| Document Type | 学位论文
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| Identifier | https://ir.lzu.edu.cn/handle/262010/223363
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| Collection | 学院待认领
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| Affiliation | 临床医学院
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Recommended Citation
GB/T 7714 |
陈曼丽. 冠心病危险因素对PCI治疗预后的影响[D]. 兰州. 兰州大学,2010.
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