兰州大学机构库 >学院待认领
甘肃省胃镜检出食管癌回顾性分析
Alternative TitleA retrospective analysis of the esophageal carcinoma diagnosed by endoscopy in Gansu
郝晓雯
Thesis Advisor黄晓俊
2008-05-24
Degree Grantor兰州大学
Place of Conferral兰州
Degree Name硕士
Keyword甘肃省 食管癌 内镜 临床流行病学 回顾性分析
Abstract【目 的】 了解甘肃省近30年间由内镜检出、经病理确诊的食管癌的临床发病特点及变化趋势,探讨食管癌发病规律,为病因学研究提供线索,为甘肃省食管癌防治规划的制定及预防效果的评价提供客观依据。 【方 法】 选择甘肃省163家医院近30年间胃镜检查并经病理确诊的食管癌患者的病历资料,对其主要的内镜下改变、临床及组织学特点进行回顾性分析。全部统计数据应用SPSS10.0软件进行分析,其中分类变量采用卡方检验,等级资料采用秩和检验。 【结 果】1977年—2006年甘肃省有效胃镜受检人数689348人,内镜检出并经病理确诊食管癌9736例,年平均检出率为1.41%。9736例食管癌平均年龄为58.22岁,中位年龄为60岁;食管癌高发于50-69岁,共占食管癌总数的68.21%。随时间推移,60岁以上老年人所占比例逐年增加,检出率高峰年龄段后移。食管癌以男性多见,9736例食管癌中,男性7726例(79.35%),女性2010例(20.65%),男:女为3.84:1。鳞癌多见(91.20%),其次为腺癌(8.78%),食管腺鳞癌极为少见(0.02%)。食管癌好发于食管中段(54.78%),其次为下段(35.90%),上段最少(8.88%)。老年患者、腺癌患者及男性患者在下段癌中所占的比例高。检出率河西地区>兰州地区>陇东南地区,其中以位于河西地区东端的武威市最高(5.07%)。 【结 论】:我省食管癌仍以鳞癌为主,腺癌无明显上升趋势。食管腺癌好发于食管下段,而鳞癌多发于食管中、上段。食管癌检出率男性高于女性,男女比例随年龄增长而呈增高趋势。女性食管癌好发部位较男性偏上。低年龄组食管癌检出率逐年降低,而高年龄组逐年增高,预示食管癌的发病率应该会在一定的时间出现下降趋势,这种下降需经历较长时间且先出现在低年龄组。检出率以武威地区最高,在当地开展食管癌早期防治工作意义重大。
Other AbstractObjective To investigate the clinical epidemiological characteristics of esophageal carcinoma and its trend during the past 30 years in Gansu province.Method Patients with esophageal carcinoma which were diagnosed by endoscopy and pathology from Jan 1977 to Dec 2006 were selected.The main clinical data,epidemiological,endoscopic manifestation and the pathological characteristics were studied .All datas collected were analyzed by a SPSS 10.0 software package with 、t test. A statistically significant difference was indicated by a P<0.05. Results Totally 689348 patients received gastroscopy examination during the past 30 years,and 9736 patients were diagnosed as esophageal carcinoma.The overall diagnosis rate of esophageal carcinoma was 1.41% in the past 30 years.The median age of the 9736 patients with esophageal carcinoma was 60 years old,with the predominant age ranged from 50 to 69 years old. The ratio between male and female was 3.84:1,which was gradually increased with increasing of age. The constituent ratio of the upper,middle,or lower segment have not changed obviously.The proportion of esophageal adenocarcinoma(8.78%) was significantly lower than squamous cancer(91.20%),and the esophageal adenosquamous was rare(0.02%).The highest rate of detection was in Wuwei(5.07%).Conclusions The proportion of esophageal adenocarcinoma was significantly lower than squamous cancer. Esophageal adenocarcinoma occurred most frequently in the lower ,but esophageal squamous cancer occurred most frequently in the middle or upper.The mean age of the esophageal cancer patients has rose over the past thirty years.Wuwei is a high-incidence area of esophageal cancer.Early prevention and control work for esophageal carcinoma in Wuwei has great significance.
URL查看原文
Language中文
Document Type学位论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/223494
Collection学院待认领
Affiliation临床医学院
Recommended Citation
GB/T 7714
郝晓雯. 甘肃省胃镜检出食管癌回顾性分析[D]. 兰州. 兰州大学,2008.
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