|Alternative Title||Distribution and antibacterial resistance of pathogens in Intensive Care Unit of the Children’s Hospital of Gansu Province
|Place of Conferral||兰州
|Other Abstract||Objective To investigate the condition of bacterial distribution and drug resistance of pathogens in Pediatric Intensive Care Unit,then instruct clinical application of antibiotics reasonably.
Methods Selected 1449 samples of hospitalized children in Pediatric Intensive Care Unit of the Children’s Hospital of Gansu Province from May 2011 to April 2012,actualized bacterial culture,then test of drug sensitivity ,and the results were statistically analyzed.
Results A total of 207 strains were included in the study.126 strains of the pathogens were Gram-negative bacilli,which were mainly Escherichia coli,Klebsiella pneumonia and Acinetobacter baumannii. Gram-postive cocci contained 61 strains,which were mainly Staphylococcus aureus, Excrement enterococcus, Epidermis staphylococcus and Streptococcus pneumonia. Fungi were 20 strains,and the most common was Candida albicans.The cefotaxime,ceftriaxone and ceftazidime resistant rates of Escherichia coli,Klebsiella pneumonia and Acinetobacter baumannii were more than 60%,the cefoperazone and sulbactam resistant rate of Escherichia coli,Klebsiella pneumonia and Acinetobacter baumannii were less than 35.3%.The penicillin resistant rate of Staphylococcus was 100%.The erythromycin resistant rate of Staphylococcus was more than 72.2%.The gentamicin resistant rate of Gram-postive cocci was more than 22.2%.No vancomycin and linezolid resistant Gram-postive cocci strains were isolated.The ketoconazole resistant rate of Candida albicans was 0.4%.
Conclusion Gram-negative bacilli,which include Escherichia coli, Klebsiella pneumonia and Acinetobacter baumannii,are dominant pathogens in Pediatric Intensive Care Unit of the Children’s Hospital of Gansu Province. Gram-postive cocci contains Staphylococcus aureus,Excrement enterococcus,Epidermis staphylococcus and Streptococcus pneumonia. The most common fungus is Candida albicans .The multi-drug resistance of pathogens are serious.It is important to carry out surveillance of bacterial resistance for appropriately using antibiotics.|
邸春阳. 甘肃省儿童医院重症监护病房病原菌分布及耐药分析[D]. 兰州. 兰州大学,2013.
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