钆塞酸二钠的临床应用研究——对肝脏恶性肿瘤诊断价值的Meta分析及对肝细胞期适宜延迟时间的初步探讨

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	钆塞酸二钠的临床应用研究——对肝脏恶性肿瘤诊断价值的Meta分析及对肝细胞期适宜延迟时间的初步探讨
Alternative Title	Gadoxetic Acid Disodium (Gd-EOB-DTPA)-Enhanced Magnetic Resonance Imaging for the Detection of hepatocellular malignant tumor:A Meta-Analysis and the relationship between the optimum delay time in hepatobiliary phase and liver function
	王寅中
Thesis Advisor	雷军强
	2014-05-27
Degree Grantor	兰州大学
Place of Conferral	兰州
Degree Name	硕士
Keyword	Gd-EOB-DTPA 普美显延迟时间磁共振动态增强肝细胞期结节特性 Child-Pugh分级肝硬化
Abstract	目的：全面评价肝功能正常或不正常的患者Gd-EOB-DTPA增强检查肝细胞期适宜的延迟时间，从而满足临床需要。方法：连续选取2013年1月-2014年1月怀疑患有肝脏占位性病变行Gd-EOB-DTPA增强检查的患者45名，在收集三期动态对比增强图像的基础上延迟5、10、20分钟采集图像，分别评估每期肝脏、肌肉、结节信号值及胆总管不同排泄时间的信号变化，计算肝脏/肌肉信号比、对比噪声比（CNR），信噪比（SNR）；回顾性按Child-Pugh肝功能分级标准分级并分组，与肝细胞期信号变化比较、分析，判定其临床意义
Other Abstract	Objective: To assess the optimum delay time in hepatobiliary phase in patients with or without normal liver function。 Methods：In 45 consecutive patients with suspected focal liver lesions, dynamic MRI was performed after intravenous Gd-EOB-DTPA, followed by hepatobiliary phases at 5, 10and 20 min. The following items were assessed at each hepatobiliary phase: parenchymal enhancement, contrast agent excretion in bile ducts, lesion enhancement characteristics,Lesion-to-liver contrast-to-noise ratios(CNR) and signal-to-noise ratios(SNR).
URL	查看原文
Language	中文
Document Type	学位论文
Identifier	https://ir.lzu.edu.cn/handle/262010/223540
Collection	学院待认领
Affiliation	临床医学院
Recommended Citation GB/T 7714	王寅中. 钆塞酸二钠的临床应用研究——对肝脏恶性肿瘤诊断价值的Meta分析及对肝细胞期适宜延迟时间的初步探讨[D]. 兰州. 兰州大学,2014.

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