| 多层螺旋CT灌注成像技术在诊断肾肿瘤中的临床应用价值 |
| Alternative Title | The clinical application in the diagnosis of renal tumors with Multi-slice spiral CT perfusion imaging
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| 马娅琼 |
| Thesis Advisor | 徐香玖
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| 2011-05-20
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| Degree Grantor | 兰州大学
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| Place of Conferral | 兰州
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| Degree Name | 硕士
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| Keyword | 肾透明细胞癌
肾错构瘤
灌注成像
分期
体层摄影术
X线计算机
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| Abstract | 目的：利用多层螺旋CT(MSCT) 灌注成像技术测定肾脏肿瘤的灌注参数值，探讨其在肿瘤定性及肾透明细胞癌临床分期中的应用价值。方法：回顾性分析经病理证实的28 例肾透明细胞癌（分Ⅰ-Ⅳ期）、20例肾错构瘤的多层螺旋CT 灌注成像结果，对肿瘤感兴趣区血流量(BF)、血容量(BV)、平均通过时间(MTT) 与表面通透性（PS）值进行统计学分析，研究其规律性。结果：（1）正常肾皮质BV/A 和BF值明显高于肾透明细胞癌和错构瘤（P < 0.01）；肾透明细胞癌BV/A和BF值明显高于肾错构瘤（P < 0.01）；正常肾皮质及肾透明细胞癌PS值明显高于肾错构瘤组（P < 0.01）（2）①肾透明细胞癌Ⅱ期、Ⅲ-Ⅳ期BV/A值、BF值与PS值明显高于肾透明细胞癌Ⅰ期患者（P < 0.05）；②肾透明细胞癌Ⅱ期与Ⅲ-Ⅳ期之间相比较：BV/A值与PS值呈上升趋势，前者有统计学意义（P < 0.05），BF值呈下降趋势，比较无统计学意义（P > 0.05）；（3）三组之间MTT值比较无统计学差异。结论：肾脏肿瘤MSCT灌注参数具有一定的规律， 在肾肿瘤的诊断中有重要的临床应用价值。 |
| Other Abstract | Objective: To investigate the qualitative and clinical stage of the renal tumor with the MSCT perfusion imaging。 Methods: Make a retrospective analysis of the relevant parametes between 28 cases of renal clear cell carcinoma (Sub-Ⅰ～Ⅳstage)and 20 cases of renal angiomyolipoma confirmed by pathology，and to study the regularities between them．Results: (1) The values of BV/A and BF in the normal renal cortex were higher than that of the renal clear cell carcinoma and angiomyolipoma significantly (P ＜ 0.01)；The values of BV/A and BF in the renal clear cell carcinoma were higher than that of the renal angiomyolipoma significantly (P ＜ 0.01)；The values of PS in normal renal cortex and renal clear cell carcinoma were higher than that of the renal angiomyolipoma significantly (P ＜ 0.01) (2) ①The values of BV/A 、BF and PS of the renal clear cell carcinoma in Ⅱ、 Ⅲ-Ⅳstage were higher than them in stage Ⅰof clear renal cell carcinoma patients significantly (P ＜ 0.05)；②The values of the Ⅱ stage and Ⅲ-Ⅳstage in renal clear cell carcinoma：the values of BV/A and PS been in a rise trend，the former has a significant difference (P ＜ 0.05)，The values of BF been in a decline trend，but has no significant difference (P ＞ 0.05) (3) The values of MTT between the three groups showed no significant difference。 Conclusion: MSCT perfusion imaging has important clinical value in the diagnosis of renal tumors in that it has certain laws in perfusion parameters． |
| URL | 查看原文
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| Language | 中文
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| Document Type | 学位论文
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| Identifier | https://ir.lzu.edu.cn/handle/262010/223614
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| Collection | 学院待认领
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| Affiliation | 临床医学院
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Recommended Citation
GB/T 7714 |
马娅琼. 多层螺旋CT灌注成像技术在诊断肾肿瘤中的临床应用价值[D]. 兰州. 兰州大学,2011.
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