| 多层螺旋CT冠状动脉钙化积分在冠心病诊断的应用及其与心功能评价的相关性 |
| Alternative Title | The Clinical Application of Coronary Artery Calcification Score with Multi-slice Spiral CT in the Diagnosis of Coronary Artery Disease and its relevance with Left ventricular function
|
| 曹平平 |
| Thesis Advisor | 徐香玖
|
| 2013-05-24
|
| Degree Grantor | 兰州大学
|
| Place of Conferral | 兰州
|
| Degree Name | 硕士
|
| Keyword | 冠状动脉粥样硬化性心脏病
体层摄影术
X线计算机
钙化积分
左心室功能
|
| Abstract | 目的：研究多层螺旋CT冠状动脉钙化积分与年龄、性别及冠状动脉狭窄之间的关系，并初步探讨冠状动脉钙化积分与心功能评价的相关性。方法：对78例同期行128层螺旋CT冠状动脉成像（CTA）及超声心动图连续患者进行回顾分析，评价钙化积分与冠脉狭窄及左室功能的关系。 结果：患者钙化积分与年龄、狭窄程度均呈正相关（r=0.389、0.361、P<0.01）,对于不同年龄组钙化积分性别差异用独立样本t检验，得出在50～70岁男女之间存在统计学差异（t=2.24、2.85,P<0.05）。冠状动脉钙化积分与左心室射血分数<50%比例存在负相关性(r=-0.93,P<0.05)。当钙化积分>100时，钙化积分值与局限性室壁运动异常发生率呈正相关（r=0.87，P<0.01）。 结论：多层螺旋CT冠脉钙化积分可用于评价冠脉粥样硬化的冠脉狭窄程度，且与左心室室壁运动异常相关，是临床冠状动脉疾病评估的重要指标。 |
| Other Abstract | Objective: To investigate Coronary Artery Calcification Score’s (CACS) correlation with Age, Gender and coronary artery stenosis and to find the relevance between CACS and left ventricular function. Methods: We reviewed the data of 78 patients who underwent both multi-slice spiral computed tomography coronary angiography (CTA) and echocardiography, then evaluated the correlation of CACS and coronary artery stenosis and left ventricular function. Results: The results showed that CACS had a positive relationship with age and the severity of coronary artery stenosis（r=0.389,0.361; P<0.01）. For the subjects 50～70 years old, there was a statistical difference (r=0.389、0.361、P<0.05) between the calcification scores of the male and female. There was a negative correlation between Coonary artey calcium score and Left ventricular ejection fraction<50% (r=-0.93, P<0.05).Patients having a CACS of 100 or higher were showed to have positive correlation with regional wall motion abnormalities (RWMAs) （r=0.87，P<0.01）. Conclusions：MSCT coronary calcification score can be applied to evaluate the severity of the coronary atherosclerosis and was correlated with the left ventricular RWMA，hence CACS could be used as a marker for the diagnosis of subclinical coronary artery disease in the clinical practice. |
| URL | 查看原文
|
| Language | 中文
|
| Document Type | 学位论文
|
| Identifier | https://ir.lzu.edu.cn/handle/262010/223615
|
| Collection | 学院待认领
|
| Affiliation | 临床医学院
|
Recommended Citation
GB/T 7714 |
曹平平. 多层螺旋CT冠状动脉钙化积分在冠心病诊断的应用及其与心功能评价的相关性[D]. 兰州. 兰州大学,2013.
|
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
