|Alternative Title||Diagnostic and Prognostic Value of Serum HE4 in Patients with Epithelial Ovarian Cancer
|Place of Conferral||兰州
|Other Abstract||Objectives：In this experimental,serum HE4 was determined by enzyme-linked immunosorbent assay in samples from overian tumor patients and healthy female volunteers.
Methods： We recruited 36 primary epithelial ovarian cancer patients,48 patients of ovarian benign masses and 32 healthy volunteers during July 2010 to July 2011 from the gynecology-oncology
1 ovarian cancer were higher than the group of benign ovarian tumors and healthy volunteers. However, the HE4 was no significant difference between ovarian benign tumor patients and healthy volunteers.
2 It is no sinificant difference between the histologic subtypes of ovarian cancer.
3 The serum HE4 values measured in stage Ⅲ-ⅣEOC patients were higher than in stage Ⅰ-Ⅱ EOC patients.
1 Serum HE4 level that was evaluated by ELISA kit of overian cancer were higher than in benign overian tumors and healthy volunteers.
2 serum HE4 has a higher sensitivity and specificity than CA125.
3 The serum HE4 after surgery was significantly lower compared with preoperative.
Key words： Epithelial ovarian cancer, tumor marker,early diagnosis|
宋晓玲. HE4在卵巢上皮性癌早期诊断及病情监测中的价值[D]. 兰州. 兰州大学,2012.
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