兰州大学机构库 >学院待认领
18F-FDG PET和99Tcm-MDP骨扫描对乳腺癌骨转移诊断价值的Meta分析
Alternative TitleThe diagnostic value of 18F-FDG PET and 99Tcm-MDP bone scintigraphy for bone metastases of breast cancer:a meta analysis
牛晶晶
Thesis Advisor徐香玖
2012-05-21
Degree Grantor兰州大学
Place of Conferral兰州
Degree Name硕士
Keyword乳腺癌 骨转移 PET 骨扫描 Meta分析
Abstract目的 应用Meta分析方法评价18F-FDG PET(氟脱氧葡萄糖正电子发射体层成像)和99Tcm-MDP(亚甲基二膦酸盐)骨扫描诊断乳腺癌骨转移的诊断价值。 方法 检索PubMed(1966-2011.5)、EMBASE(1974-2011.5)、Cochrane 图书馆(1993-2011.5)及中国生物医学文献数据库(CBM,1978-2011.5)、中国期刊全文数据库(CNKI,1994-2011.5)、中文科技期刊数据库(VIP,1989-2011.5)、万方数字化期刊群(1982-2011.5)等数据库,计算合并敏感度、特异度、诊断比值比及其95%可信区间(95%CI)和SROC曲线下面积(AUC)。 结果 共纳入6个研究(222例患者/1349个病灶),Meta分析结果显示:与手术、病理相比结论 当前证据提示,99Tcm-MDP骨扫描可以作为乳腺癌患者骨转移筛查的首选方法,而当MDP显像呈不典型骨病变且临床怀疑骨转移时,可考虑行PET显像确诊。
Other AbstractObjective To perform a meta-analysis to evaluate the diagnostic accuracy of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) and technetium-99m methylene diphosphonate (MDP) bone scintigraphy (BS) in osseous metastases detection in patients with breast cancer. Methods Studies were systematically searched in the PubMed(1966-2011.5), EMBASE(1974-2011.5), the Cochrane library(1993-2011.5), CBM(1978-2011.5), CNKI(1994-2011.5), VIP (1989-2011.5)and WanFang databases(1982-2011.5). Additional studies were manually searched using the references of the retrieved articles.
URL查看原文
Language中文
Document Type学位论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/224306
Collection学院待认领
Affiliation临床医学院
Recommended Citation
GB/T 7714
牛晶晶. 18F-FDG PET和99Tcm-MDP骨扫描对乳腺癌骨转移诊断价值的Meta分析[D]. 兰州. 兰州大学,2012.
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