兰州大学机构库 >生命科学学院
Ethnic Differences Shape the Alpha but Not Beta Diversity of Gut Microbiota from School Children in the Absence of Environmental Differences
Liu, Ke1; Zhang, Yongling1; Li, Qinglin1; Li, Huan1; Long, Danfeng1; Yan, Shijuan1,2; Huang, Wenjie2; Long, Ruijun3; Huang, Xiaodan1
2020-02
Source PublicationMICROORGANISMS   Impact Factor & Quartile Of Published Year  The Latest Impact Factor & Quartile
EISSN2076-2607
Volume8Issue:2
page numbers15
AbstractAlthough the human gut microbiome is shaped by factors such as diet, environment, and genetic background, most studies investigating the relationship between ethnicity and microbiota have compared groups living in separate geographical locations. To isolate the effects of ethnicity on microbial diversity by minimizing environmental differences, we selected 143 school children from Han, Tibetan, and Hui populations from the same town on the Qinghai-Tibetan Plateau for fecal microbiome 16S rDNA sequencing. We characterized the diversity, identified signature taxa, and performed correlation analysis between diet and community composition. Firmicutes (47.61%) and Bacteroidetes (38.05%) were dominant phyla among the three ethnic groups; seven genera showed significant differences in relative abundance. Tibetan populations had a higher relative abundance of Oscillibacter and Barnesiella, compared with Han and Hui populations. Alpha diversity analyses (observed species, ACE, and Shannon indices) showed that the Tibetan population had the highest diversity compared to the Hui and Han groups, whereas beta diversity analysis revealed no significant differences between groups. The consumption of grains, milk, eggs, and fruits were positively correlated with specific taxa. Under similar environments and diet, ethnic background significantly contributed to differences in alpha diversity but not beta diversity of gut microbiota.
KeywordQinghai Tibetan Plateau dietary habit ethnicity gut microbial diversity Miseq
PublisherMDPI
DOI10.3390/microorganisms8020254
Indexed BySCIE
Language英语
Funding ProjectNSFC[31500101][31661143020] ; fundamental research funds for the central university[lzujbky-2019-48][lzujbky-2018-16] ; special fund for scientific innovation strategy-construction of high level Academy of Agriculture Science[R2017PY-QY005]
WOS Research AreaMicrobiology
WOS SubjectMicrobiology
WOS IDWOS:000519618200110
PublisherMDPI
Original Document TypeArticle
PMID 32075068
Citation statistics
Document Type期刊论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/419162
Collection生命科学学院
Corresponding AuthorLong, Ruijun; Huang, Xiaodan
Affiliation
1.Lanzhou Univ, Sch Publ Hlth, 222 TianshuiNanlu, Lanzhou 730000, Peoples R China
2.Guangzhou Acad Agr Sci, Agrobiol Gene Res Ctr, Guangzhou 510640, Peoples R China
3.Lanzhou Univ, Sch Life Sci, 222 TianshuiNanlu, Lanzhou 730000, Peoples R China
Recommended Citation
GB/T 7714
Liu, Ke,Zhang, Yongling,Li, Qinglin,et al. Ethnic Differences Shape the Alpha but Not Beta Diversity of Gut Microbiota from School Children in the Absence of Environmental Differences[J]. MICROORGANISMS,2020,8(2).
APA Liu, Ke.,Zhang, Yongling.,Li, Qinglin.,Li, Huan.,Long, Danfeng.,...&Huang, Xiaodan.(2020).Ethnic Differences Shape the Alpha but Not Beta Diversity of Gut Microbiota from School Children in the Absence of Environmental Differences.MICROORGANISMS,8(2).
MLA Liu, Ke,et al."Ethnic Differences Shape the Alpha but Not Beta Diversity of Gut Microbiota from School Children in the Absence of Environmental Differences".MICROORGANISMS 8.2(2020).
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