兰州大学机构库
Biologically active isoquinoline alkaloids covering 2014-2018
Shang, Xiao-Fei1,2; Yang, Cheng-Jie1; MorrisNatschke, Susan L.3; Li, Jun-Cai1; Yin, Xiao-Dan1; Liu, YQ(刘映前)1; Guo, Xiao4; Peng, Jing-Wen1; Goto, Masuo3; Zhang, Ji-Yu2; Lee, Kuo-Hsiung3,5
2020-07-29
Online publication date2020-07
Source PublicationMEDICINAL RESEARCH REVIEWS   Impact Factor & Quartile Of Published Year  The Latest Impact Factor & Quartile
ISSN0198-6325
EISSN1098-1128
Volume40Issue:6Pages:2212-2289
page numbers78
AbstractIsoquinoline alkaloids, an important class ofN-based heterocyclic compounds, have attracted considerable attention from researchers worldwide since the early 19th century. Over the past 200 years, many compounds from this class were isolated, and most of them and their analogs possess various bioactivities. In this review, we survey the updated literature on bioactive alkaloids and highlight research achievements of this alkaloid class during the period of 2014-2018. We reviewed over 400 molecules with a broad range of bioactivities, including antitumor, antidiabetic and its complications, antibacterial, antifungal, antiviral, antiparasitic, insecticidal, anti-inflammatory, antioxidant, neuroprotective, and other activities. This review should provide new indications or directions for the discovery of new and better drugs from the original naturally occurring isoquinoline alkaloids.
Keywordantitumor berberine biological activities isoquinoline alkaloids
PublisherWILEY
DOI10.1002/med.21703
Indexed BySCIE
Language英语
Funding ProjectKey Program for International S&T Cooperation Projects of China Gansu Province[18YF1WA115] ; National Natural Science Foundation of China[21672092][31371975][31772790] ; National Key Research and Development Program of China[2017YFD0201404][2016YFE0129000] ; Central Public-Interest Scientific Institution Basal Research Fund[Y2019XK14] ; NIH from the National Cancer Institute[CA177584]
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000553350000001
PublisherWILEY
Original Document TypeReview
PMID 32729169
Citation statistics
Document Type期刊论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/441794
Collection兰州大学
药学院
Corresponding AuthorLiu, Ying-Qian; Lee, Kuo-Hsiung
Affiliation
1.Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China
2.Chinese Acad Agr Sci, Lanzhou Inst Husb & Pharmaceut Sci, Lanzhou, Peoples R China
3.Univ N Carolina, UNC Eshelman Sch Pharm, Nat Prod Res Labs, Chapel Hill, NC 27599 USA
4.China Med Univ & Hosp, Chinese Med Res & Dev Ctr, Taichung, Taiwan
5.Qinghai Univ, Tibetan Med Coll, Tibetan Med Res Ctr, Xining, Peoples R China
First Author AffilicationSchool of Pharmacy
Corresponding Author AffilicationSchool of Pharmacy
First Signature AffilicationSchool of Pharmacy
Recommended Citation
GB/T 7714
Shang, Xiao-Fei,Yang, Cheng-Jie,MorrisNatschke, Susan L.,et al. Biologically active isoquinoline alkaloids covering 2014-2018[J]. MEDICINAL RESEARCH REVIEWS,2020,40(6):2212-2289.
APA Shang, Xiao-Fei.,Yang, Cheng-Jie.,MorrisNatschke, Susan L..,Li, Jun-Cai.,Yin, Xiao-Dan.,...&Lee, Kuo-Hsiung.(2020).Biologically active isoquinoline alkaloids covering 2014-2018.MEDICINAL RESEARCH REVIEWS,40(6),2212-2289.
MLA Shang, Xiao-Fei,et al."Biologically active isoquinoline alkaloids covering 2014-2018".MEDICINAL RESEARCH REVIEWS 40.6(2020):2212-2289.
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