| Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis | |
| 2021-01-14 | |
| Source Publication | Frontiers in Pharmacology Impact Factor & Quartile |
| ISSN | 1663-9812 |
| Volume | 11 |
| page numbers | 7 |
| Abstract | Tripterygium wilfordii Hook F (TwHF) is one of the most commonly used and effective traditional Chinese herbal medicines against rheumatoid arthritis (RA). Both Tripterygium Glycoside Tablets (TGT) and Tripterygium wilfordii Tablets (TWT) are the representative TwHF-based agents enrolled into the 2019 edition of Medicine Catalog for National Basic Medical Insurance, Injury Insurance, and Maternity Insurance. However, individual differences in TGT/TWT response across patients usually exist in the process of treating RA, implying that the clinical application of the two agents may not be standardized leading to the ineffective treatment and the risk of side effects. Growing evidence show that the bioactive constituents of TwHF may often have toxicity, the package insert of TGT and TWT may not be described in detail, and the therapeutic windows of the two agents are narrow. Thus, it is an urgent task to develop a standardized clinical practice guideline for TGT and TWT in the treatment of RA. In the current study, a group of clinical experts of traditional Chinese medicine and Western medicine in the research field of rheumatism diseases, pharmacists, and methodologists of evidence-based medicine were invited to select the clinical questions, to determine the levels of the evidence and the strength of the recommendations, and to develop the recommendations and good practice points. The guideline is formed based on the combination of clinical research evidence and expert experience (evidence-based, consensus, supplemented by experience). The clinical problems which are supported by clinical evidence may form recommendations, and the clinical problems without clinical evidence may form experts' suggestions. Both recommendations and experts' suggestions in this guideline summarized the clinical indications, usage, dosage, combined medication, and safety of TGT and TWT against RA systematically and comprehensively, which may offer a professional guidance in the context of the clinical application of the two TwHF-based agents. |
| Keyword | Tripterygium glycoside tablet Tripterygium wilfordii tablets rheumatoid arthritis clinical practice guideline rational drug use |
| Publisher | FRONTIERS MEDIA SA |
| DOI | 10.3389/fphar.2020.608703 |
| Indexed By | SCOPUS ; SCIE |
| Language | 英语 |
| WOS Research Area | Pharmacology & Pharmacy |
| WOS Subject | Pharmacology & Pharmacy |
| WOS ID | WOS:000612798100001 |
| Original Document Type | Article |
| PMID | 33519474 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | https://ir.lzu.edu.cn/handle/262010/448986 |
| Collection | 兰州大学 |
| Corresponding Author | Lin, Na |
| Affiliation | 1.China Acad Chinese Med Sci, Inst Chinese Mat Med, Beijing, Peoples R China; 2.China Acad Chinese Med Sci, Guanganmen Hosp, Beijing, Peoples R China; 3.Tianjin Univ Tradit Chinese Med, Teaching Hosp 1, Tianjin, Peoples R China; 4.Anhui Univ Tradit Chinese Med, Affiliated Hosp 1, Hefei, Peoples R China; 5.Guangdong Prov Hosp Tradit Chinese Med, Guangzhou, Peoples R China; 6.Fujian Univ Tradit Chinese Med, Peoples Hosp 2, Fuzhou, Peoples R China; 7.Huazhong Univ Sci & Technol, Tongji Med Sch, Tongji Hosp, Wuhan, Peoples R China; 8.Hubei Prov Hosp Tradit Chinese Med, Dept Honghu, Honghu, Peoples R China; 9.Beijing Univ Chinese Med, Affiliated Hosp 3, Beijing, Peoples R China; 10.Capital Med Univ, Xuanwu Hosp, Beijing, Peoples R China; 11.Henan Univ Tradit Chinese Med, Affiliated Hosp 1, Zhengzhou, Peoples R China; 12.Army Med Univ, Southwest Hosp, Chongqing, Peoples R China; 13.Beijing Univ Chinese Med, Ctr Evidence Based Chinese Med, Beijing, Peoples R China; 14.Bethune Int Peace Hosp, Peoples Liberat Army, Shijiazhuang, Hebei, Peoples R China; 15.Shanghai Guanghua Hosp Integrated Tradit & Wester, Shanghai, Peoples R China; 16.Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, Lanzhou, Peoples R China; 17.Henan Rheumatism Hosp, Zhengzhou, Peoples R China; 18.China Japan Friendship Hosp, Beijing, Peoples R China; 19.Peking Univ, Shenzhen Hosp, Shenzhen, Peoples R China; 20.Zhongnan Hosp Wuhan Univ, Ctr Evidence Based & Translat Med, Wuhan, Peoples R China; 21.China Acad Chinese Med Sci, Inst Basic Res Clin Med, Beijing, Peoples R China |
| Recommended Citation GB/T 7714 | Lin, Na,Zhang, Yan-Qiong,Jiang, Quan,et al. Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis[J]. Frontiers in Pharmacology,2021,11. |
| APA | Lin, Na.,Zhang, Yan-Qiong.,Jiang, Quan.,Liu, Wei.,Liu, Jian.,...&Wang, Xiao-Yue.(2021).Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis.Frontiers in Pharmacology,11. |
| MLA | Lin, Na,et al."Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis".Frontiers in Pharmacology 11(2021). |
| Files in This Item: | There are no files associated with this item. | ||||
