| Status of Immunotherapy Acceptance in Chinese Patients With Multiple Sclerosis: Analysis of Multiple Sclerosis Patient Survival Report 2018 | |
| 2021-04-08 | |
| Source Publication | Frontiers in Neurology Impact Factor & Quartile |
| ISSN | 1664-2295 |
| Volume | 12 |
| page numbers | 12 |
| Abstract | Objective: The prevalence of multiple sclerosis (MS) in China is low, although it has been increasing recently. Owing to the paucity of data on immunotherapy acceptance in the Chinese population, we conducted this study to analyze factors affecting the acceptance of immunotherapy and selection of disease-modifying therapies (DMTs) based on personal and clinical data of patients with MS. Methods: In this study, data were obtained from the Multiple Sclerosis Patient Survival Report 2018, which was the first national survey of patients with MS in China. There were 1,212 patients with MS from 31 provinces who were treated at 49 Chinese hospitals over a 4-month period from May 2018 to August 2018, and the patients were asked to complete online questionnaires to assess their understanding of the disease. Results: In general, highly educated patients with frequent relapses were more willing to receive treatment regardless of DMTs or other immunotherapy, and patients with more understanding of the disease opted to be treated. Younger patient population, patients with severe disease course, and those with more symptoms were likely to choose the treatment. Moreover, a higher proportion of women chose to be treated with DMTs than with other immunotherapies. Conclusions: Education status and patient awareness of the disease impact the treatment acceptance in Chinese patients with MS. Therefore, we call for improving the awareness of MS disease and social security to help patients to improve their quality of life. |
| Keyword | multiple sclerosismulticenter studydisease-modifying therapiesimmunosuppressive drugdrug selection |
| Publisher | FRONTIERS MEDIA SA |
| DOI | 10.3389/fneur.2021.651511 |
| Indexed By | SCOPUS ; SCIE |
| Language | 英语 |
| WOS Research Area | Neurosciences & Neurology |
| WOS Subject | Clinical NeurologyNeurosciences |
| WOS ID | WOS:000642089000001 |
| Original Document Type | Article |
| PMID | 33897605 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | https://ir.lzu.edu.cn/handle/262010/450299 |
| Collection | 兰州大学 |
| Corresponding Author | Zeng, Qiuming; Yang, Huan |
| Affiliation | 1.Cent South Univ, Xiangya Hosp, Dept Neurol, Changsha, Peoples R China; 2.Chinese Acad Med Sci & Peking Union Med Coll, Dept Neurol, Peking Union Med Coll Hosp, Beijing, Peoples R China; 3.Hebei Med Univ, Dept Neurol, Second Hosp, Shijiazhuang, Hebei, Peoples R China; 4.Zhengzhou Univ, Affiliated Hosp 1, Dept Neurol, Zhengzhou, Peoples R China; 5.Harbin Med Univ, Affiliated Hosp 2, Dept Neurol, Harbin, Peoples R China; 6.Sichuan Univ, West China Hosp, Dept Neurol, Chengdu, Peoples R China; 7.Shanxi Med Univ, Dept Neurol, Affiliated Hosp 1, Taiyuan, Peoples R China; 8.Chongqing Med Univ, Dept Neurol, Affiliated Hosp 1, Chongqing, Peoples R China; 9.First Hosp Jilin Univ, Dept Neurol, Changchun, Peoples R China; 10.First Hosp Jilin Univ, Neurosci Ctr, Changchun, Peoples R China; 11.Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; 12.Capital Med Univ, Beijing Tongren Hosp, Dept Neurol, Beijing, Peoples R China; 13.Wenzhou Med Univ, Dept Neurol, Affiliated Hosp 1, Wenzhou, Peoples R China; 14.Peking Univ First Hosp, Dept Neurol, Beijing, Peoples R China; 15.Tianjin Med Univ Gen Hosp, Dept Neurol, Tianjin, Peoples R China; 16.Huazhong Univ Sci & Technol, Tongji Hosp, Dept Neurol, Tongji Med Coll, Wuhan, Peoples R China; 17.Inner Mongolia Med Univ, Dept Neurol, Affiliated Hosp, Hohhot, Peoples R China; 18.Capital Med Univ, Xuanwu Hosp, Dept Neurol, Beijing, Peoples R China; 19.Fujian Med Univ, Dept Neurol, Affiliated Hosp 1, Fuzhou, Peoples R China; 20.Sun Yat Sen Univ, Dept Neurol, Affiliated Hosp 1, Guangzhou, Peoples R China; 21.Gen Hosp Peoples Liberat Army, Dept Neurol, Beijing, Peoples R China; 22.Lanzhou Univ, Dept Neurol, Second Hosp, Lanzhou, Peoples R China; 23.Guangxi Med Univ, Affiliated Hosp 1, Dept Neurol, Nanning, Peoples R China; 24.Southern Med Univ, Nanfang Hosp, Dept Neurol, Guangzhou, Peoples R China; 25.Guangzhou Med Univ, Dept Neurol, Affiliated Hosp 2, Guangzhou, Peoples R China; 26.Dalian Med Univ, Dept Neurol, Affiliated Hosp 1, Dalian, Peoples R China; 27.Xiamen Univ, Affiliated Zhongshan Hosp, Dept Neurol, Xiamen, Peoples R China |
| Recommended Citation GB/T 7714 | Zhou, Ran,Zeng, Qiuming,Yang, Huan,et al. Status of Immunotherapy Acceptance in Chinese Patients With Multiple Sclerosis: Analysis of Multiple Sclerosis Patient Survival Report 2018[J]. Frontiers in Neurology,2021,12. |
| APA | Zhou, Ran.,Zeng, Qiuming.,Yang, Huan.,Xu, Yan.,Tan, Guojun.,...&Zheng, Weihong.(2021).Status of Immunotherapy Acceptance in Chinese Patients With Multiple Sclerosis: Analysis of Multiple Sclerosis Patient Survival Report 2018.Frontiers in Neurology,12. |
| MLA | Zhou, Ran,et al."Status of Immunotherapy Acceptance in Chinese Patients With Multiple Sclerosis: Analysis of Multiple Sclerosis Patient Survival Report 2018".Frontiers in Neurology 12(2021). |
| Files in This Item: | |||||
| File Name/Size | DocType | Version | Access | License | |
| 10.3389@fneur.2021.6（2947KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | View Application Full Text |
