兰州大学机构库
LncRNA-mediated cell autophagy: An emerging field in bone destruction in rheumatoid arthritis
Lei, Hai-Tao1,2,5; Wang, Jin-Hai3; Yang, Hui-Jun1,2; Wu, Hai-Juan1,2; Nian, Fang-Hong1,2; Jin, Fang-Mei1,2; Yang, Jing4; Tian, Xue-Mei1,2; Wang, Hai-Dong1,2
2023-12
Source PublicationBIOMEDICINE & PHARMACOTHERAPY   Impact Factor & Quartile
ISSN0753-3322 ; 1950-6007
EISSN1950-6007
Volume168
page numbers10
AbstractIn recent years, research on the mechanism of bone destruction in rheumatoid arthritis (RA) has remained in the initial stages, and the mechanism has not been fully elucidated to date. Recent studies have shown that long noncoding RNAs (lncRNAs) participate in RA bone destruction via autophagy, but the specific regulatory mechanism of lncRNA-mediated autophagy is unclear. Therefore, in this article, we review the mechanisms of lncRNA-mediated autophagy in fibroblast-like synoviocytes and chondrocytes in RA bone destruction. We explain that lncRNAs mediate autophagy and participate in many specific pathological processes of RA bone destruction by regulating signalling pathways and the expression of target genes. Specific lncRNAs can be used as markers for molecular diagnosis, mechanistic regulation, treatment and prognosis of RA.
KeywordLncRNAs Autophagy Bone destruction Signalling pathway Rheumatoid arthritis Review
PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI10.1016/j.biopha.2023.115716
Indexed BySCIE
Language英语
WOS Research AreaResearch & Experimental Medicine ; Pharmacology & Pharmacy
WOS SubjectMedicine, Research & Experimental ; Pharmacology & Pharmacy
WOS IDWOS:001094613700001
Original Document TypeReview
PMID 37866
Citation statistics
Document Type期刊论文
Identifierhttps://ir.lzu.edu.cn/handle/262010/569112
Collection兰州大学
Corresponding AuthorTian, Xue-Mei; Wang, Hai-Dong
Affiliation
1.Gansu Prov Hosp Tradit Chinese Med, Dept Rheumatol, Lanzhou 730050, Gansu, Peoples R China;
2.Gansu Prov Hosp Tradit Chinese Med, Orthoped Ctr, Lanzhou 730050, Gansu, Peoples R China;
3.Lanzhou Univ, Tradit Chinese Med Dept, Hosp 2, Lanzhou 730030, Gansu, Peoples R China;
4.Gansu Univ Chinese Med, Clin Coll Tradit Chinese Med, Lanzhou 730000, Gansu, Peoples R China;
5.Gansu Prov Tradit Chinese Med, 418 Guazhou Rd, Lanzhou, Gansu, Peoples R China
Recommended Citation
GB/T 7714
Lei, Hai-Tao,Wang, Jin-Hai,Yang, Hui-Jun,et al. LncRNA-mediated cell autophagy: An emerging field in bone destruction in rheumatoid arthritis[J]. BIOMEDICINE & PHARMACOTHERAPY,2023,168.
APA Lei, Hai-Tao.,Wang, Jin-Hai.,Yang, Hui-Jun.,Wu, Hai-Juan.,Nian, Fang-Hong.,...&Wang, Hai-Dong.(2023).LncRNA-mediated cell autophagy: An emerging field in bone destruction in rheumatoid arthritis.BIOMEDICINE & PHARMACOTHERAPY,168.
MLA Lei, Hai-Tao,et al."LncRNA-mediated cell autophagy: An emerging field in bone destruction in rheumatoid arthritis".BIOMEDICINE & PHARMACOTHERAPY 168(2023).
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