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新白叶藤碱衍生物 Z24对灰葡萄孢菌的作用机制及靶标研究
学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:
赵文斌
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  |  
  
Submit date:2023/11/15
新白叶藤碱衍生物Z24
neocryptolepine derivative Z24
灰葡萄孢菌
B. cinerea
分子靶标
molecular target
硫胺噻唑合酶
thiaminothiazole synthase
可变剪接
variable splicing
硫胺素代谢
thiamine metabolism
虚拟筛选
virtual screening
刺激响应性嘌呤霉素前药和嘌呤霉素衍生物 的合成及生物应用
学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:
chang bingbing
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  |  
  
Submit date:2023/11/15
嘌呤霉素
Puromycin
刺激响应性前药
Stimuli-responsive prodrugs
内源性刺激
Endogenous stimuli
外源性刺激
Exogenous stimuli
二硫/二硒结构
Disulfide/diselenide scaffolds
硫氧还蛋白还原酶
Thioredoxin reductase
谷胱甘肽
Glutathione
二硫苏糖醇
Dithiothreitol
1,2,3-三氮唑
1,2,3-Triazoles
基于质谱技术筛选缺血性卒中的组学标志物
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
崔家博
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  |  
  
Submit date:2023/11/15
缺血性卒中
Ischemic stroke
质谱技术
Mass spectrometry technology
蛋白质组学
Proteomics
代谢组学
Metabolomics
抑制糖代谢酶PDK活性对胃癌放疗增敏作用的研究
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
乔万佳
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  |  
  
Submit date:2023/11/15
胃癌
Gastric cancer
Pyruvate dehydrogenase kinase
放射治疗
Radiation therapy
Sodium dichloroacetate
丙酮酸脱氢酶激酶
二氯乙酸钠
Active oxygen
活性氧
The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur
期刊论文
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 18, 页码: 10586-10600
Authors:
Song, Yingjie
;
Zhang, Siping
;
Ye, Zirui
;
Song, Yongyan
;
Chen, Lin
;
Tong, Aiping
;
He, YX(何永兴)
;
Bao, Rui
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  |  
  
Submit date:2022/11/09
Tavaborole-Induced Inhibition of the Aminoacyl-tRNA Biosynthesis Pathway against Botrytis cinerea Contributes to Disease Control and Fruit Quality Preservation
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022, 卷号: 70, 期号: 39, 页码: 12297-12309
Authors:
Zhao, Wen-Bin
;
An, Jun-Xia
;
Hu, Yong-Mei
;
Li, An-Ping
;
Zhang, Shao-Yong
;
Zhang, Bao-Qi
;
Zhang, ZJ(张智军)
;
Luo, Xiong-Fei
;
Bian, Qiang
;
Ma, Yue
...
Zhao, Wen-Bin
;
An, Jun-Xia
;
Hu, Yong-Mei
;
Li, An-Ping
;
Zhang, Shao-Yong
;
Zhang, Bao-Qi
;
Zhang, ZJ(张智军)
;
Luo, Xiong-Fei
;
Bian, Qiang
;
Ma, Yue
;
Ding, Yan-Yan
;
Wang, Rui
;
Liu, YQ(刘映前)
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  |  
  
Submit date:2022/11/08
Amino acids
Biochemistry
Biosynthesis
Cell proliferation
Controlled drug delivery
Disease control
Quality control
Aminoacyl
Aminoacyl-tRNA synthetase
Biosynthesis pathways
Botrytis cinerea
Control quality
Fruit quality
Inhibitory effect
Membrane integrity
Synthetases
Tavaborole
Tavaborole-Induced Inhibition of the Aminoacyl-tRNA Biosynthesis Pathway against Botrytis cinerea Contributes to Disease Control and Fruit Quality Preservation
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022
Authors:
Zhao, Wen-Bin
;
An, Jun-Xia
;
Hu, Yong-Mei
;
Li, An-Ping
;
Zhang, Shao-Yong
;
Zhang, Bao-Qi
;
Zhang, ZJ(张智军)
;
Luo, Xiong-Fei
;
Bian, Qiang
;
Ma, Yue
...
Zhao, Wen-Bin
;
An, Jun-Xia
;
Hu, Yong-Mei
;
Li, An-Ping
;
Zhang, Shao-Yong
;
Zhang, Bao-Qi
;
Zhang, ZJ(张智军)
;
Luo, Xiong-Fei
;
Bian, Qiang
;
Ma, Yue
;
Ding, Yan-Yan
;
Wang, Rui
;
Liu, YQ(刘映前)
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  |  
  
Submit date:2022/11/09
Botrytis cinerea
tavaborole
membrane integrity
aminoacyl-tRNA synthetases
EFNA3 Is a Prognostic Biomarker Correlated With Immune Cell Infiltration and Immune Checkpoints in Gastric Cancer
期刊论文
FRONTIERS IN GENETICS, 2022, 卷号: 12
Authors:
Zheng, Peng
;
Liu, XiaoLong
;
Li, Haiyuan
;
Gao, Lei
;
Yu, Yang
;
Wang, Na
;
Chen, Hao
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  |  
  
Submit date:2022/04/20
gastric cancer
EFNA3
prognosis biomarkers
immune infiltrates
immune checkpoints
Metabolic responses of plasma to extreme environments in overwintering Tibetan frogs Nanorana parkeri: a metabolome integrated analysis
期刊论文
Frontiers in Zoology, 2021, 卷号: 18, 期号: 1
Authors:
Niu, Yonggang
;
Zhang, Xuejing
;
Zhang, Haiying
;
Xu, Tisen
;
Zhu, Lifeng
;
Storey, Kenneth B.
;
Chen, Qiang
Favorite
  |  
  
Submit date:2021/12/15
Overwintering
Nanorana parkeri
Metabolomics
Plasma
不同气候区及乳酸菌影响玉米青贮发酵的微生物组与代谢组学机制研究
学位论文
理学博士, 兰州: 兰州大学, 2021
Authors:
许冬梅
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  |  
  
Submit date:2021/12/06
微生物组
代谢组
气候因子
全株玉米
乳酸菌添加剂