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兰州大学机构库

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Antimicrobial activity of natural and semi-synthetic carbazole alkaloids 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259
Authors:  Ding, Yan-Yan;  Zhou, Han;  Peng-Deng, Bao-Qi;  Zhang, Bao-Qi;  Zhang, Zhi-Jun;  Wang, Guang-Han;  Zhang, Shao-Yong;  Wu, Zheng-Rong;  Wang, Yi-Rong;  Liu, Ying-Qian...Ding, Yan-Yan;  Zhou, Han;  Peng-Deng, Bao-Qi;  Zhang, Bao-Qi;  Zhang, Zhi-Jun;  Wang, Guang-Han;  Zhang, Shao-Yong;  Wu, Zheng-Rong;  Wang, Yi-Rong;  Liu, Ying-Qian
Favorite  |    Submit date：2023/11/28
Carbazole  Alkaloids  Antibacterial activity  Antifungal activity  
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139
Authors:  Zhang, Mi;  Zhu, Li-Zu;  Yang, Cheng-Jie;  Yan, Jia-Xuan;  Wang, Zhi-Ping;  Bai, Yin-Peng;  Peng, Li-Zeng;  Luo, Hong-Bo;  Zhang, Zhi-Jun;  Li, Lei...Zhang, Mi;  Zhu, Li-Zu;  Yang, Cheng-Jie;  Yan, Jia-Xuan;  Wang, Zhi-Ping;  Bai, Yin-Peng;  Peng, Li-Zeng;  Luo, Hong-Bo;  Zhang, Zhi-Jun;  Li, Lei;  Xu, Chuan-Rui;  Liu, Ying-Qian
Favorite  |    Submit date：2023/11/28
Anti -tumor activity  Camptothecin  Fluorine  Synthesis  Hepatocellular carcinoma  
新白叶藤碱衍生物 Z24对灰葡萄孢菌的作用机制及靶标研究 学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:  赵文斌
Favorite  |    Submit date：2023/11/15
新白叶藤碱衍生物Z24  neocryptolepine derivative Z24  灰葡萄孢菌  B. cinerea  分子靶标  molecular target  硫胺噻唑合酶  thiaminothiazole synthase  可变剪接  variable splicing  硫胺素代谢  thiamine metabolism  虚拟筛选  virtual screening  
Design, synthesis, and biological evaluation of 1-styrenyl isoquinoline derivatives for anti-hepatocellular carcinoma activity and effect on mitochondria 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256
Authors:  Wang, Yuqing;  Long, Lin;  Zhuo, Linsheng;  Zhang, Honghua;  Luo, Tian;  Deng, Jiedan;  Wang, Yuying;  Li, Zhao;  Wang, Zhen;  Peng, Xue...Wang, Yuqing;  Long, Lin;  Zhuo, Linsheng;  Zhang, Honghua;  Luo, Tian;  Deng, Jiedan;  Wang, Yuying;  Li, Zhao;  Wang, Zhen;  Peng, Xue
Favorite  |    Submit date：2023/07/18
Hepatocellular carcinoma  Mitochondria  1-Styryl isoquinoline  Resveratrol  Apoptosis  
N(14)-substituted evodiamine derivatives as dual topoisomerase 1/tubuli- n-Inhibiting anti-gastrointestinal tumor agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 255
Authors:  Deng, Jiedan;  Long, Lin;  Peng, Xue;  Jiang, Weifan;  Peng, Ying;  Zhang, Xi;  Zhao, Yuting;  Tian, Ying;  Wang, Zhen;  Zhuo, Linsheng...Deng, Jiedan;  Long, Lin;  Peng, Xue;  Jiang, Weifan;  Peng, Ying;  Zhang, Xi;  Zhao, Yuting;  Tian, Ying;  Wang, Zhen;  Zhuo, Linsheng
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Top 1  tubulin inhibitor  Evodiamine derivatives  Anti -Tumor  
Highly oxygenated germacrane-type sesquiterpenoids from the whole plant of Salvia cavaleriei H.L'ev. and their biological activities 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 211
Authors:  Chen, Xiao-Han;  Liu, Xu;  Cui, Wen-Bo;  An, Feng-Li;  Liu, Li;  Wu, Qian;  Yu, Jian-Ning;  Dai, Jian-Ye;  Zhang, Zhan-Xin;  Fei, Dong-Qing...Chen, Xiao-Han;  Liu, Xu;  Cui, Wen-Bo;  An, Feng-Li;  Liu, Li;  Wu, Qian;  Yu, Jian-Ning;  Dai, Jian-Ye;  Zhang, Zhan-Xin;  Fei, Dong-Qing
Favorite  |    Submit date：2023/07/18
Salvia cavalerieiH  H.Lev  Lamiaceae  Germacrane-type sesquiterpenoids  Anti-inflammatory  Neuroprotective  Phytotoxic  
Tumor-targeting engineered probiotic Escherichia coli Nissle 1917 inhibits colorectal tumorigenesis and modulates gut microbiota homeostasis in mice 期刊论文
LIFE SCIENCES, 2023, 卷号: 324
Authors:  Tang, Haibo;  Zhou, Tuoyu;  Jin, Weilin;  Zong, Simin;  Mamtimin, Tursunay;  Salama, El-Sayed;  Jeon, Byong-Hun;  Liu, Pu;  Han, Huawen;  Li, Xiangkai...Tang, Haibo;  Zhou, Tuoyu;  Jin, Weilin;  Zong, Simin;  Mamtimin, Tursunay;  Salama, El-Sayed;  Jeon, Byong-Hun;  Liu, Pu;  Han, Huawen;  Li, Xiangkai
Favorite  |    Submit date：2023/07/18
Engineered probiotic  Escherichia coli Nissle 1917  AOM  DSS model  Tumor-targeting treatment  Gut microbiota  
Lanatoside C decelerates proliferation and induces apoptosis through inhibition of STAT3 and ROS-mediated mitochondrial membrane potential transformation in cholangiocarcinoma 期刊论文
Frontiers in Pharmacology, 2023, 卷号: 14
Authors:  Zhang, Chao;  Yang, Hong-Ying;  Gao, Long;  Bai, Ming-Zhen;  Fu, Wen-Kang;  Huang, Chong-Fei;  Mi, Ning-Ning;  Ma, Hai-Dong;  Lu, Ya-Wen;  Jiang, Ning-Zu...Zhang, Chao;  Yang, Hong-Ying;  Gao, Long;  Bai, Ming-Zhen;  Fu, Wen-Kang;  Huang, Chong-Fei;  Mi, Ning-Ning;  Ma, Hai-Dong;  Lu, Ya-Wen;  Jiang, Ning-Zu;  Tian, Liang;  Cai, Teng;  Lin, Yan-Yan;  Zheng, Xing-Xing;  Gao, Kun;  Chen, Jian-Jun;  Meng, Wen-Bo
Favorite  |    Submit date：2023/11/28
Lanatoside C  cholangiocarcinoma  reactive oxygen species  mitochondrial membrane potential  stat3  apoptosis  
小分子药物对细胞氧化还原系统的调控及机制研究 学位论文
理学博士, 兰州: 兰州大学, 2023
Authors:  Miao Zhong
Favorite  |    Submit date：2023/11/15
氧化还原  Redox  活性氧  Reactive oxygen species  抑制剂  Inhibitors  光动力治疗  Photodynamic therapy  Bmi1  Bmi1  
利用超声靶向微泡破坏技术沉默 PDLIM5 探索非小细胞性 肺癌自噬与耐药关系的实验研究 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  张瑶
Favorite  |    Submit date：2023/11/15
非小细胞性肺癌  Non-small-cell lung cancer (NSCLC)  肿瘤细胞耐药  Drug resistance of tumor cell  超声微泡靶向破坏技术  Ultrasound targeted microbubble destruction (UTMD)  纳米材料  nanomaterials  PDLIM5  PDLIM5  细胞自噬  autophagy  基因沉默  gene silencing