兰州大学机构库

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Endomorphins: potential roles and therapeutic indications in the development of opioid peptide analgesic drugs 期刊论文
MEDICINAL RESEARCH REVIEWS, 2012, 卷号: 32, 期号: 3, 页码: 536-580
Authors:  Liu, WX;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Inst Biochem & Mol Biol, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci,State Key Lab Appl Organ Chem, 222 Tianshui S Rd, Lanzhou 730000, Peoples R China.
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Endomorphins  Analgesic Drugs  Structure-activity Relationships  Bioavailability  Blood-brain Barrier  
The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2010, 卷号: 628, 期号: 1-3, 页码: 42-50
Authors:  Dai, X;  Song, HJ;  Cui, SG;  Wang, T;  Liu, Q;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 222 Tian Shui S Rd, Lanzhou 730000, Peoples R China.
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Endomorphin-1  Endomorphin-2  Deltorphin I  Angiogenesis  HUVEC  
C-terminal amide to alcohol conversion changes the cardiovascular effects of endomorphins in anesthetized rats 期刊论文
PEPTIDES, 2006, 卷号: 27, 期号: 1, 页码: 136-143
Authors:  Yu, Y;  Wang, CL;  Cui, Y;  Fan, YZ;  Liu, J;  Shao, X;  Liu, HM;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Dept Biochem & Mol Biol, 222 Tian Shui S Rd, Lanzhou 730000, Peoples R China.
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endomorphin1-ol  endomorphin2-ol  C-terminal amide to alcohol  conversion  DD25  system arterial pressure  heart rate  
Endogenous opioid peptides, endomorphin-1 and -2 and deltorphin I, stimulate angiogenesis in the CAM assay 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2008, 卷号: 579, 期号: 1-3, 页码: 269-275
Authors:  Dai, X;  Cui, SG;  Wang, T;  Liu, Q;  Song, HJ;  Wang, R(王锐);  Wang, R (reprint author), Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, State Key Lab Chinese Med & Mol Pharmacol, Kowloon, Hong Kong, Peoples R China.
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endomorphin-1  endomorphin-2  deltorphin 1  angiogenesis  CAM  
Abnormal modulation of cholinergic neurotransmission by endomorphin 1 and endomorphin 2 in isolated bronchus of type 1 diabetic rats 期刊论文
PEPTIDES, 2006, 卷号: 27, 期号: 11, 页码: 2770-2777
Authors:  Yu, Y;  Wang, X;  Cui, Y;  Fan, YZ;  Liu, J;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Dept Biochem & Mol Biol, Sch Life Sci, 222 Tian Shui S Rd, Lanzhou 730000, Peoples R China.
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type 1 diabetic rats  endomorphin 1  endomorphin 2  electrical field stimulation  cholinergic bronchoconstriction  
Design, Synthesis, and Pharmacological Characterization of Novel Endomorphin-1 Analogues as Extremely Potent mu-Opioid Agonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 7, 页码: 3102-3114
Authors:  Liu, X;  Wang, Y;  Xing, YH;  Yu, J;  Ji, H;  Kai, M;  Wang, ZL;  Wang, D;  Zhang, YX;  Zhao, DP...Liu, X;  Wang, Y;  Xing, YH;  Yu, J;  Ji, H;  Kai, M;  Wang, ZL;  Wang, D;  Zhang, YX;  Zhao, DP;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
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Endomorphin-1 analogs with enhanced metabolic stability and systemic analgesic activity: Design, synthesis, and pharmacological characterization 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 卷号: 15, 期号: 4, 页码: 1694-1702
Authors:  Liu, HM;  Zhang, BZ(张邦治);  Liu, XF;  Wang, CL;  Ni, JM(倪京满);  Wang, R(王锐);  Ni, JM (reprint author), Lanzhou Univ, Sch Life Sci, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
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endomorphin-1  systematic chemical modification  metabolic stability  antinociceptive activity  
A New Class of Highly Potent and Selective Endomorphin-1 Analogues Containing alpha-Methylene-beta-aminopropanoic Acids (Map) 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 13, 页码: 6224-6236
Authors:  Wang, Y;  Xing, YH;  Liu, X;  Ji, H;  Kai, M;  Chen, ZY;  Yu, J;  Zhao, DP;  Ren, H;  Wang, R(王锐)...Wang, Y;  Xing, YH;  Liu, X;  Ji, H;  Kai, M;  Chen, ZY;  Yu, J;  Zhao, DP;  Ren, H;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Inst Biochem & Mol Biol,Sch Life Sci, Lanzhou 730000, Peoples R China.
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Endomorphin 1[psi] and endomorphin 2[psi], endomorphins analogues containing a reduced (CH2NH) amide bond between Tyr(1) and Pro(2), display partial agonist potency but significant antinociception 期刊论文
LIFE SCIENCES, 2005, 卷号: 77, 期号: 10, 页码: 1155-1165
Authors:  Zhao, QY;  Chen, Q(陈强);  Yang, DJ;  Feng, Y;  Long, Y;  Wang, P;  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Dept Biochem & Mol Biol, Lanzhou 730000, Peoples R China.
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endomorphins  analogues  reduced amide bond  antinociception  intracebroventricular  tail-flick  formalin-model  
Endomorphin1 and endomorphin2, endogenous potent inhibitors of electrical field stimulation (EFS)-induced cholinergic contractions of rat isolated bronchus 期刊论文
PEPTIDES, 2006, 卷号: 27, 期号: 7, 页码: 1846-1851
Authors:  Yu, Y;  Cui, Y;  Wang, X;  Fan, YZ;  Liu, J;  Yan, X(严祥);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Dept Biochem & Mol Biol, 222 Tian Shui S Rd, Lanzhou 73000, Peoples R China.
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endomorphin1  endomorphin2  endogenous MOR agonists  electrical field stimulation  cholinergic bronchoconstriction