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兰州大学机构库

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新型酸激活肽的设计、合成及抗肿瘤活性研究 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  常琳琳
Favorite  |    Submit date：2023/11/15
抗癌肽  anticancer peptides  穿膜肽  cell penetrating peptides  酸激活  acid-activated  抗肿瘤活性  antitumor activity  低毒性  low toxicity  
New designed pH-responsive histidine-rich peptides with antitumor activity 期刊论文
JOURNAL OF DRUG TARGETING, 2021, 卷号: 29, 期号: 6, 页码: 651-659
Authors:  Chang, Linlin;  Bao, Hexin;  Yao, Jia;  Liu, Hui;  Gou, Sanhu;  Zhong, Chao;  Zhang, Yun;  Ni, Jingman
Favorite  |    Submit date：2021/04/16
Histidine-rich peptide  acid-activatable  antitumor  high efficiency  low toxicity  
Tryptic Stability and Antimicrobial Activity of the Derivatives of Polybia-CP with Fine-Tuning Modification in the Side Chain of Lysine 期刊论文
International Journal of Peptide Research and Therapeutics, 2020, 卷号: 27, 期号: 2, 页码: 851-862
Authors:  Jia, Fengjing;  Liang, Xiaolei;  Wang, Jiayi;  Zhang, Lishi;  Zhou, Jingjing;  He, Yuhang;  Zhang, Fangfang;  Yan, Wenjin;  Wang, Kairong
Adobe PDF(2182Kb)  |  Favorite  |    Submit date：2020/12/18
Cationic antimicrobial peptide  Polybia-CP  Tryptic stability  Fine-tuning of side chain  
Diversity of Antimicrobial Peptides in Three Partially Sympatric Frog Species in Northeast Asia and Implications for Evolution 期刊论文
GENES, 2020, 卷号: 11, 期号: 2
Authors:  Wang, Qing;  Xia, Rui;  Ji, Jing Jing;  Zhu, Qian;  Li, Xiao Ping;  Ma, Yue;  Xu, Yan Chun
Adobe PDF(5625Kb)  |  Favorite  |    Submit date：2020/08/04
antimicrobial peptides  transcriptome  diversity  frog  adaptive evolution  
Enhanced Fluorescence for Bioassembly by Environment-Switching Doping of Metal Ions 期刊论文
Advanced Functional Materials, 2020, 卷号: 30, 期号: 10
Authors:  Tao, Kai;  Chen, Yu;  Orr, Asuka A.;  Tian, Zhen;  Makam, Pandeeswar;  Gilead, Sharon;  Si, MS(司明苏);  Rencus-Lazar, Sigal;  Qu, Songnan;  Zhang, Mingjun...Tao, Kai;  Chen, Yu;  Orr, Asuka A.;  Tian, Zhen;  Makam, Pandeeswar;  Gilead, Sharon;  Si, MS(司明苏);  Rencus-Lazar, Sigal;  Qu, Songnan;  Zhang, Mingjun;  Tamamis, Phanourios;  Gazit, Ehud
Adobe PDF(1228Kb)  |  Favorite  |    Submit date：2020/08/04
aromatic cyclodipeptides  bioinspired LEDs  metal ion doping  supramolecular fluorescence  very initial oligomerization  
Design of a new pH-activatable cell-penetrating peptide for drug delivery into tumor cells 期刊论文
Chemical Biology & Drug Design, 2019, 卷号: 94, 期号: 5, 页码: 1884-1893
Authors:  Zhang, Yun;  Li, Li;  Chang, Linlin;  Liu, Hui;  Song, Jingjing;  Liu, Yue;  Bao, Hexin;  Liu, Beijun;  Wang, Rui;  Ni, Jingman...Zhang, Yun;  Li, Li;  Chang, Linlin;  Liu, Hui;  Song, Jingjing;  Liu, Yue;  Bao, Hexin;  Liu, Beijun;  Wang, Rui;  Ni, Jingman
Favorite  |    Submit date：2020/08/20
acid-activated  anticancer drug delivery  cell-penetrating peptides  low cytotoxicity  pH-dependent antitumor activity  
Design of new acid-activated cell-penetrating peptides for tumor drug delivery 期刊论文
PeerJ, 2017, 卷号: 6
Authors:  Yao, J;  Ma, YY;  Zhang, W;  Li, L;  Zhang, Y;  Zhang, L;  Liu, H;  Ni, JM;  Wang, R;  Ni, JM (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou, Gansu, Peoples R China....Yao, J;  Ma, YY;  Zhang, W;  Li, L;  Zhang, Y;  Zhang, L;  Liu, H;  Ni, JM;  Wang, R;  Ni, JM (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou, Gansu, Peoples R China.
Favorite  |    Submit date：2018/01/19
Cell-penetrating peptide  PH-sensitivity  TH analogs  Antitumor  
Stearylated Antimicrobial Peptide Melittin and Its Retro Isomer for Efficient Gene Transfection 期刊论文
BIOCONJUGATE CHEMISTRY, 2013, 卷号: 24, 期号: 11, 页码: 1805-1812
Authors:  Zhang, W;  Song, JJ;  Liang, RR;  Zheng, X;  Chen, JB;  Li, GL;  Zhang, BZ(张邦治);  Yan, X(严祥);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Sch Basic Med Sci, Inst Biochem & Mol Biol,Key Lab Preclin Study New, Lanzhou 730000, Peoples R China....Zhang, W;  Song, JJ;  Liang, RR;  Zheng, X;  Chen, JB;  Li, GL;  Zhang, BZ(张邦治);  Yan, X(严祥);  Wang, R(王锐);  Wang, R (reprint author), Lanzhou Univ, Sch Life Sci, Sch Basic Med Sci, Inst Biochem & Mol Biol,Key Lab Preclin Study New, Lanzhou 730000, Peoples R China.
Adobe PDF(411Kb)  |  Favorite  |    Submit date：2015/12/14
Design of an Acid-Activated Antimicrobial Peptide for Tumor Therapy 期刊论文
MOLECULAR PHARMACEUTICS, 2013, 卷号: 10, 期号: 8, 页码: 2934-2941
Authors:  Song, JJ;  Zhang, W;  Kai, M;  Chen, JB;  Liang, RR;  Zheng, X;  Li, GL;  Zhang, BZ(张邦治);  Wang, KR;  Zhang, Y...Song, JJ;  Zhang, W;  Kai, M;  Chen, JB;  Liang, RR;  Zheng, X;  Li, GL;  Zhang, BZ(张邦治);  Wang, KR;  Zhang, Y;  Yang, ZB;  Ni, JM(倪京满);  Wang, R(王锐);  Ni, JM (reprint author), Lanzhou Univ, Sch Pharm, 222 South Tianshui Rd, Lanzhou 730000, Peoples R China.
Adobe PDF(553Kb)  |  Favorite  |    Submit date：2015/12/22
antimicrobial peptide  antitumor  acid activate  low toxicity  enzymatic stability  
Targeted molecular dynamics (TMD) of the full-length KcsA potassium channel: on the role of the cytoplasmic domain in the opening process 期刊论文
JOURNAL OF MOLECULAR MODELING, 2013, 卷号: 19, 期号: 4
Authors:  Li, Y;  Barbault, F;  Delamar, M;  Zhang, RS(张瑞生);  Hu, RJ(胡荣静);  Delamar, M (reprint author), Univ Paris Diderot, ITODYS, UMR CNRS 7086, 15 Rue J-A de Baif, F-75013 Paris, France.
Adobe PDF(1603Kb)  |  Favorite  |    Submit date：2014/12/05
Cytoplasmic domain  Full-length KcsA  pH sensor  Targeted molecular dynamics (TMD)