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Itaconate诱导DC免疫耐受缓解AIH发病的生物学机制研究
学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:
张奇煜
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  |  
  
Submit date:2023/11/15
自身免疫性肝炎
Autoimmune Hepatitis
衣康酸
Itaconate
树突状细胞
Dendritic cells
自噬
Autophagy
mTOR信号
mTOR signalling
Dual-targetable fluorescent probe for mapping the fluctuation of peroxynitrite in drug-induced liver injury model
期刊论文
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2023, 卷号: 286
Authors:
Wang, Yingzhe
;
Liu, Yu
;
Song, Xuerui
;
Feng, Y(冯燕)
;
Jing, Chunlin
;
Zhang, GL(张国林)
;
Huang, Yongwei
;
Liu, WS(刘伟生)
Favorite
  |  
  
Submit date:2023/01/03
Biocompatibility
Diagnosis
Diseases
Fluorescence
Mitochondria
Drug-induced liver injury
Endogenous ONOO−
Fluorescent probes
Injury models
Liver injuries
Liver-targeted
Mitochondrial-targeted
Mitochondrias
Peroxynitrites
Therapeutic effects
Dual-targetable fluorescent probe for mapping the fluctuation of peroxynitrite in drug-induced liver injury model
期刊论文
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2023, 卷号: 286
Authors:
Wang, Yingzhe
;
Liu, Yu
;
Song, Xuerui
;
Feng, Y(冯燕)
;
Jing, Chunlin
;
Zhang, GL(张国林)
;
Huang, Yongwei
;
Liu, WS(刘伟生)
Favorite
  |  
  
Submit date:2023/07/18
Biocompatibility
Diagnosis
Diseases
Fluorescence
Mitochondria
Drug-induced liver injury
Endogenous ONOO−
Fluorescent probes
Injury models
Liver injuries
Liver-targeted
Mitochondrial-targeted
Mitochondrias
Peroxynitrites
Therapeutic effects
Dual-targetable fluorescent probe for mapping the fluctuation of peroxynitrite in drug-induced liver injury model
期刊论文
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2023, 卷号: 286
Authors:
Wang, Yingzhe
;
Liu, Yu
;
Song, Xuerui
;
Feng, Y(冯燕)
;
Jing, Chunlin
;
Zhang, GL(张国林)
;
Huang, Yongwei
;
Liu, WS(刘伟生)
Favorite
  |  
  
Submit date:2023/04/12
Biocompatibility
Diagnosis
Diseases
Fluorescence
Mitochondria
Drug-induced liver injury
Endogenous ONOO−
Fluorescent probes
Injury models
Liver injuries
Liver-targeted
Mitochondrial-targeted
Mitochondrias
Peroxynitrites
Therapeutic effects
7, 8-Dihydroxy-4-methyl coumarin alleviates cholestasis via activation of the Farnesoid X receptor in vitro and in vivo
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 370
Authors:
Refat, Moath
;
Zhang, Guoqiang
;
Saad, Abdulaziz Ahmed
;
Baldi, Salem
;
Zheng, Fang
;
Wu, Xin 'an
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  |  
  
Submit date:2023/04/12
8-Dihydroxy-4-methylcoumarin
Farnesoid X receptor
Hepatic transporters
Liver enzymes
Cholestatic liver injuries
Cholestasis
The role of hepatic microenvironment in hepatic fibrosis development
期刊论文
ANNALS OF MEDICINE, 2022, 卷号: 54, 期号: 1, 页码: 2830-2844
Authors:
Meng, Ying
;
Zhao, Tong
;
Zhang, Zhengyi
;
Zhang, Dekui
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  |  
  
Submit date:2023/01/03
Hepatic fibrosis
microenvironment
therapy
Development of peroxynitrite-responsive fluorescence probe for recognition of drug-induced liver injury
期刊论文
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2022, 卷号: 283
Authors:
Wang, Bing-Dan
;
Wei, Ran
;
Gao, Meng-Jiao
;
Wang, Yi-Hua
;
Zhang, Chu-Fan
;
Guo, Xiao-Han
;
Liang, Zi-shan
;
Zhou, Jia-Tong
;
Sun, Jia-Xing
;
Xu, Jia-Qi
...
Wang, Bing-Dan
;
Wei, Ran
;
Gao, Meng-Jiao
;
Wang, Yi-Hua
;
Zhang, Chu-Fan
;
Guo, Xiao-Han
;
Liang, Zi-shan
;
Zhou, Jia-Tong
;
Sun, Jia-Xing
;
Xu, Jia-Qi
;
Kang, Yan-Fei
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  |  
  
Submit date:2023/01/03
Cells
Cytology
Diagnosis
Diseases
Fluorescence
Physiology
Active substance
Balance functions
Bio-imaging
Cell functions
Fluorescence probes
Liver injuries
Living cell
Peroxynitrites
Physiological process
Zebrafish
Screening and validation of biomarkers for cadmium-induced liver injury based on targeted bile acid metabolomics
期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 300
Authors:
Tian, Meng
;
Yan, Jun
;
Zhang, Honglong
;
Wei, Yuhui
;
Zhang, Mingtong
;
Rao, Zhi
;
Zhang, Mingkang
;
Wang, Haiping
;
Wang, Yanping
;
Li, X(李汛)
...
Tian, Meng
;
Yan, Jun
;
Zhang, Honglong
;
Wei, Yuhui
;
Zhang, Mingtong
;
Rao, Zhi
;
Zhang, Mingkang
;
Wang, Haiping
;
Wang, Yanping
;
Li, X(李汛)
Favorite
  |  
  
Submit date:2022/07/01
Biomarkers
Chlorine compounds
Heavy metals
High performance liquid chromatography
III-V semiconductors
Mass spectrometry
Rats
Bile acid
Biochemical parameters
Cadmium exposure
Glycolithocholic acids
Liver injuries
Metabolomics
Rat livers
Sprague-Dawley rats
Toxic heavy metals
Liver injury
Bile acid (BA)
Screening and validation of biomarkers for cadmium-induced liver injury based on targeted bile acid metabolomics
期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 300
Authors:
Tian, Meng
;
Yan, Jun
;
Zhang, Honglong
;
Wei, Yuhui
;
Zhang, Mingtong
;
Rao, Zhi
;
Zhang, Mingkang
;
Wang, Haiping
;
Wang, Yanping
;
Li, X(李汛)
...
Tian, Meng
;
Yan, Jun
;
Zhang, Honglong
;
Wei, Yuhui
;
Zhang, Mingtong
;
Rao, Zhi
;
Zhang, Mingkang
;
Wang, Haiping
;
Wang, Yanping
;
Li, X(李汛)
Favorite
  |  
  
Submit date:2022/11/08
Mass spectrometry
Cadmium chloride
Diseases
Heavy metals
Chlorine compounds
High performance liquid chromatography
Rats
Bile acid
Biochemical parameters
Cadmium exposure
Glycolithocholic acids
Liver injuries
Metabolomics
Rat livers
Sprague-Dawley rats
Toxic heavy metals
Impact of Liver Functions by Repurposed Drugs for COVID-19 Treatment
期刊论文
Journal of Clinical and Translational Hepatology, 2022, 卷号: 10, 期号: 4, 页码: 748-756
Authors:
Zhang, Rongzhi
;
Wang, Qiang
;
Yang, Jianshe
Adobe PDF(618Kb)
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  |  
  
Submit date:2022/07/01
Liver injury
Hepatotoxicity
COVID-19
Antivirals
Aminotransferases
DILI