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Mitochondria-targeted ruthenium(II)-based phosphorescent chemodosimeter for peroxynitrite detection in drug-induced liver injury
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2023, 卷号: 396
Authors:
Kou, Manchang
;
Wang, Kun
;
Zhang, Xinfeng
;
Cui, Xiang
;
Zhang, Wanchao
;
Wang, Baoyan
;
Tang, Xiaoliang
;
Liu, Weisheng
Favorite
  |  
  
Submit date:2023/11/28
Ruthenium complex
Peroxynitrite
Chemodosimeter
Mitochondria
Drug-induced liver injury
New insights into regulatory cell death and acute pancreatitis
期刊论文
Heliyon, 2023, 卷号: 9, 期号: 7
Authors:
Li, Hongyao
;
Wu, Ding
;
Zhang, Haidan
;
Li, Peiwu
Favorite
  |  
  
Submit date:2023/11/28
Acute pancreatitis
RCD
Autophagy
Necroptosis
Pyroptosis
Ferroptosis
MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products
期刊论文
Aging and Disease, 2023
Authors:
Chan, Ka Iong
;
Zhang, Siyuan
;
Li, Guodong
;
Xu, Yida
;
Cui, Liao
;
Wang, Yitao
;
Su, Huanxing
;
Tan, Wen
;
Zhong, Zhangfeng
Favorite
  |  
  
Submit date:2023/11/28
MYC
cancer
immune response
multidrug resistance
natural product
herbal medicine
Pharmacokinetics, absorption and transport mechanism for ginseng polysaccharides
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 162
Authors:
Zhang, Juanhong
;
He, Jiaxin
;
Huang, Jumin
;
Li, Xuefeng
;
Fan, Xiaoqing
;
Li, Wenbin
;
Wu, Guofan
;
Xie, Chun
;
Fan, Xing-Xing
;
Zhang, Junmim
...
Zhang, Juanhong
;
He, Jiaxin
;
Huang, Jumin
;
Li, Xuefeng
;
Fan, Xiaoqing
;
Li, Wenbin
;
Wu, Guofan
;
Xie, Chun
;
Fan, Xing-Xing
;
Zhang, Junmim
;
Yao, Xiaojun
;
Wang, Rong
;
Leung, Elaine Lai-Han
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  |  
  
Submit date:2023/11/28
Panax ginseng
Ginseng polysaccharide
Pharmacokinetics
Absorption
HPLC-MS/MS
Lattice proteins
SMAD2 转录激活 BUB1 增强 TGFβ 信号途 径促进肝癌 DNA 损伤、增殖以及迁移
学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:
齐文博
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  |  
  
Submit date:2023/11/15
肝细胞癌, BUB1, SMAD2,增殖和迁移, TGFβ 信号通路
HCC
BUB1
SMAD2
proliferation and migration
TGFβ signaling pathway
MCC-950通过抑制NLRP3介导的细胞焦亡对小鼠肠淤血再灌注损伤的改善作用
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
蒲唯高
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  |  
  
Submit date:2023/11/15
肠淤血再灌注损伤
Intestinal congestion reperfusion injury (ICRI)
细胞焦亡
nucleotide-binding oligomerization domain-like receptor protein 3
核苷酸结合寡聚化结构域样受体蛋 白 3
pyroptosis
半胱氨酸天冬酶 1
Caspase 1
共表达IL-7/IL-21靶向c-Met的CAR-T细胞在治疗胃癌的临床前研究
学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:
张正潮
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  |  
  
Submit date:2023/11/15
胃癌
Gastric cancer
c-Met
c-Met
组织芯片
Tissue chip
靶向治疗
Targeted therapy
单克隆抗体
Monoclonal antibody
微流控技术
Microfluidic technology
scFv
scFv
CAR-T
CAR-T
IL-7
IL-7
IL-21
IL-21
免疫治疗
Immunotherapy
PDX模型
PDX model
吴茱萸碱衍生物的设计合成及抗肝细胞癌活性研究
学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:
雷芳
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  |  
  
Submit date:2023/11/15
吴茱萸碱衍生物
evodiamine derivatives
肝细胞癌
hepatocellular carcinoma
构效关系
structure-activity relationship
Top1/Top2双重抑制剂
Top1/Top2 dual inhibitor
抗癌活性
anticancer activity
Itaconate诱导DC免疫耐受缓解AIH发病的生物学机制研究
学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:
张奇煜
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  |  
  
Submit date:2023/11/15
自身免疫性肝炎
Autoimmune Hepatitis
衣康酸
Itaconate
树突状细胞
Dendritic cells
自噬
Autophagy
mTOR信号
mTOR signalling
HSTP1修饰的huc-MSCs来源的外泌体治疗肝纤维化实验研究
学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:
林岩
Favorite
  |  
  
Submit date:2023/11/15
外泌体
exosomes
人脐带间充质干细胞
human umbilical cord mesenchymal stem cells
肝纤维化
liver fibrosis
肝星状细胞
hepatic stellate cells
靶向肽
targeting peptide