兰州大学机构库

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Mitochondria-targeted ruthenium(II)-based phosphorescent chemodosimeter for peroxynitrite detection in drug-induced liver injury 期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2023, 卷号: 396
Authors:  Kou, Manchang;  Wang, Kun;  Zhang, Xinfeng;  Cui, Xiang;  Zhang, Wanchao;  Wang, Baoyan;  Tang, Xiaoliang;  Liu, Weisheng
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Ruthenium complex  Peroxynitrite  Chemodosimeter  Mitochondria  Drug-induced liver injury  
New insights into regulatory cell death and acute pancreatitis 期刊论文
Heliyon, 2023, 卷号: 9, 期号: 7
Authors:  Li, Hongyao;  Wu, Ding;  Zhang, Haidan;  Li, Peiwu
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Acute pancreatitis  RCD  Autophagy  Necroptosis  Pyroptosis  Ferroptosis  
MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products 期刊论文
Aging and Disease, 2023
Authors:  Chan, Ka Iong;  Zhang, Siyuan;  Li, Guodong;  Xu, Yida;  Cui, Liao;  Wang, Yitao;  Su, Huanxing;  Tan, Wen;  Zhong, Zhangfeng
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MYC  cancer  immune response  multidrug resistance  natural product  herbal medicine  
Pharmacokinetics, absorption and transport mechanism for ginseng polysaccharides 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 162
Authors:  Zhang, Juanhong;  He, Jiaxin;  Huang, Jumin;  Li, Xuefeng;  Fan, Xiaoqing;  Li, Wenbin;  Wu, Guofan;  Xie, Chun;  Fan, Xing-Xing;  Zhang, Junmim...Zhang, Juanhong;  He, Jiaxin;  Huang, Jumin;  Li, Xuefeng;  Fan, Xiaoqing;  Li, Wenbin;  Wu, Guofan;  Xie, Chun;  Fan, Xing-Xing;  Zhang, Junmim;  Yao, Xiaojun;  Wang, Rong;  Leung, Elaine Lai-Han
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Panax ginseng  Ginseng polysaccharide  Pharmacokinetics  Absorption  HPLC-MS/MS  Lattice proteins  
SMAD2 转录激活 BUB1 增强 TGFβ 信号途 径促进肝癌 DNA 损伤、增殖以及迁移 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  齐文博
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肝细胞癌, BUB1, SMAD2,增殖和迁移, TGFβ 信号通路  HCC  BUB1  SMAD2  proliferation and migration  TGFβ signaling pathway  
MCC-950通过抑制NLRP3介导的细胞焦亡对小鼠肠淤血再灌注损伤的改善作用 学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:  蒲唯高
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肠淤血再灌注损伤  Intestinal congestion reperfusion injury (ICRI)  细胞焦亡  nucleotide-binding oligomerization domain-like receptor protein 3  核苷酸结合寡聚化结构域样受体蛋 白 3  pyroptosis  半胱氨酸天冬酶 1  Caspase 1  
共表达IL-7/IL-21靶向c-Met的CAR-T细胞在治疗胃癌的临床前研究 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  张正潮
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胃癌  Gastric cancer  c-Met  c-Met  组织芯片  Tissue chip  靶向治疗  Targeted therapy  单克隆抗体  Monoclonal antibody  微流控技术  Microfluidic technology  scFv  scFv  CAR-T  CAR-T  IL-7  IL-7  IL-21  IL-21  免疫治疗  Immunotherapy  PDX模型  PDX model  
吴茱萸碱衍生物的设计合成及抗肝细胞癌活性研究 学位论文
医学硕士, 兰州: 兰州大学, 2023
Authors:  雷芳
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吴茱萸碱衍生物  evodiamine derivatives  肝细胞癌  hepatocellular carcinoma  构效关系  structure-activity relationship  Top1/Top2双重抑制剂  Top1/Top2 dual inhibitor  抗癌活性  anticancer activity  
Itaconate诱导DC免疫耐受缓解AIH发病的生物学机制研究 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  张奇煜
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自身免疫性肝炎  Autoimmune Hepatitis  衣康酸  Itaconate  树突状细胞  Dendritic cells  自噬  Autophagy  mTOR信号  mTOR signalling  
HSTP1修饰的huc-MSCs来源的外泌体治疗肝纤维化实验研究 学位论文
医学博士, 兰州: 兰州大学, 2023
Authors:  林岩
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外泌体  exosomes  人脐带间充质干细胞  human umbilical cord mesenchymal stem cells  肝纤维化  liver fibrosis  肝星状细胞  hepatic stellate cells  靶向肽  targeting peptide