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A self-assembled nanophotosensitizer targets lysosomes and induces lysosomal membrane permeabilization to enhance photodynamic therapy
期刊论文
Chemical Science, 2023, 卷号: 14, 期号: 19, 页码: 5106-5115
Authors:
Li, Youyou
;
Han, Wenbo
;
Gong, Deyan
;
Luo, Taokun
;
Fan, Yingjie
;
Mao, Jianming
;
Qin, Wenwu
;
Lin, Wenbin
Favorite
  |  
  
Submit date:2023/05/25
Cell proliferation
Lipid bilayers
Molecular dynamics
Photosensitizers
Self assembly
Tumors
Amphiphilics
Breast tumour
Co-localization studies
Dynamics simulation
Light irradiations
Live-cell imaging
Lysosomal membranes
Membrane permeabilization
Photosensitiser
Sub-cellular
烯烃装订构建高效的两亲性细胞穿膜肽的研究及应用
学位论文
理学博士, 兰州: 兰州大学, 2021
Authors:
李墅
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  |  
  
Submit date:2023/11/15
细胞穿膜肽
cell penetrating peptides, stapled peptide
装订肽
α-helices
α螺旋
amphipathic character,
两亲性特征
cellular uptake
细胞摄取
endosomal escape..
内体逃逸.
Cytotoxic Effect of Graphene Oxide Nanoribbons on Escherichia coli
期刊论文
NANOMATERIALS, 2021, 卷号: 11, 期号: 5
Authors:
Qiang, Shirong
;
Li, Zhengbin
;
Zhang, Li
;
Luo, Dongxia
;
Geng, Rongyue
;
Zeng, Xueli
;
Liang, Jianjun
;
Li, Ping
;
Fan, Qiaohui
Adobe PDF(2673Kb)
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Submit date:2021/06/17
graphene oxide nanoribbonsEcolicytotoxic effectoxidative stresscytomembrane damage
Biologically active indolizidine alkaloids
期刊论文
MEDICINAL RESEARCH REVIEWS, 2020, 卷号: 41, 期号: 2, 页码: 928-960
Authors:
Zhang, Junmin
;
Morris-Natschke, Susan L.
;
Ma, Di
;
Shang, Xiao-Fei
;
Yang, Chen-Jie
;
Liu, Ying-Qian
;
Lee, Kuo-Hsiung
Adobe PDF(5020Kb)
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  |  
  
Submit date:2020/12/18
biological activity
indolizidine alkaloids
natural products
pharmacological effects
Exploration of ovine milk whey proteome during postnatal development using an iTRAQ approach
期刊论文
PeerJ, 2020, 卷号: 8
Authors:
Zhang, Xueying
;
Li, Fadi
;
Qin, Fang
;
Li, Wanhong
;
Yue, Xiangpeng
Adobe PDF(2731Kb)
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  |  
  
Submit date:2020/12/20
Hu sheep
iTRAQ
LC-MS/MS
Proteomics
Whey protein
The protective effects of angelica organic acid against ox-LDL-induced autophagy dysfunction of HUVECs
期刊论文
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2020, 卷号: 20, 期号: 1
Authors:
Li, Xuefeng
;
Zhou, Jing
;
Dou, Yinghuan
;
Shi, Yanbin
;
Wang, Ying
;
Hong, Jianli
;
Zhao, Junnan
;
Zhang, Jiaying
;
Yuan, Yang
;
Zhou, Mengru
...
Li, Xuefeng
;
Zhou, Jing
;
Dou, Yinghuan
;
Shi, Yanbin
;
Wang, Ying
;
Hong, Jianli
;
Zhao, Junnan
;
Zhang, Jiaying
;
Yuan, Yang
;
Zhou, Mengru
;
Wei, Xiangxiang
Adobe PDF(6496Kb)
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Submit date:2020/12/18
Angelica organic acid
Ferulic acid
Ox-LDL
Autophagic flux
Atherosclerosis
RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1
期刊论文
Cancer Medicine, 2019, 卷号: 9, 期号: 4, 页码: 1529-1543
Authors:
Wang, Tao
;
Zhang, Wei-Sheng
;
Wang, Zheng-Xia
;
Wu, Zhi-Wei
;
Du, Bin-Bin
;
Li, Lai-Yuan
;
Chen, Yi-Feng
;
Yang, Xiong-Fei
;
Hao, Xiang-Yong
;
Guo, Tian-Kang
...
Wang, Tao
;
Zhang, Wei-Sheng
;
Wang, Zheng-Xia
;
Wu, Zhi-Wei
;
Du, Bin-Bin
;
Li, Lai-Yuan
;
Chen, Yi-Feng
;
Yang, Xiong-Fei
;
Hao, Xiang-Yong
;
Guo, Tian-Kang
Adobe PDF(3665Kb)
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Submit date:2020/08/06
colorectal cancer
cyclinA2
mTORC1
proliferation
RAPTOR
URB1
Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism
期刊论文
Scientific Reports, 2019, 卷号: 9
Authors:
Law, Betty Yuen Kwan
;
Michelangeli, Francesco
;
Qu, Yuan Qing
;
Xu, Su-Wei
;
Han, Yu
;
Mok, Simon Wing F. Ai
;
Dias, Ivo Ricardo de Seabra Rodrigues
;
Javed, Masood-ul-Hassan
;
Chan, Wai-Kit
;
Xue, Wei-Wei
...
Law, Betty Yuen Kwan
;
Michelangeli, Francesco
;
Qu, Yuan Qing
;
Xu, Su-Wei
;
Han, Yu
;
Mok, Simon Wing F. Ai
;
Dias, Ivo Ricardo de Seabra Rodrigues
;
Javed, Masood-ul-Hassan
;
Chan, Wai-Kit
;
Xue, Wei-Wei
;
Yao, Xiao-Jun
;
Zeng, Wu
;
Zhang, Hui
;
Wang, Jing-Rong
;
Liu, Liang
;
Wong, Vincent Kam Wai
Adobe PDF(12936Kb)
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Submit date:2020/08/04
PPAR delta inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell
期刊论文
International Journal of Medical Sciences, 2019, 卷号: 16, 期号: 12, 页码: 1593-1603
Authors:
Li, Yi
;
Wang, Chenwei
;
Lu, Jiyuan
;
Huang, Ke
;
Hang, Yu
;
Chen, Junlin
;
Yang, Yan
;
Liu, Bin
Adobe PDF(2560Kb)
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Submit date:2020/08/06
Non-alcoholic fatty liver disease
PPAR delta
L02 Cell
BODIPY based phenylthiourea derivatives as highly selective MeHg
+
and Hg
2+
ions fluorescent chemodosimeter and its application to bioimaging
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2017, 卷号: 243, 页码: 195-202
Authors:
Deng, Min
;
Gong, Deyan
;
Han, Shi-Chong
;
Zhu, Xiangtao
;
Iqbal, Anam
;
Liu, WS(刘伟生)
;
Tan, WW(覃文武)
;
Guo, Huichen
Adobe PDF(1531Kb)
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Submit date:2020/07/17