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A self-assembled nanophotosensitizer targets lysosomes and induces lysosomal membrane permeabilization to enhance photodynamic therapy
期刊论文
Chemical Science, 2023, 卷号: 14, 期号: 19, 页码: 5106-5115
Authors:
Li, Youyou
;
Han, Wenbo
;
Gong, Deyan
;
Luo, Taokun
;
Fan, Yingjie
;
Mao, Jianming
;
Qin, Wenwu
;
Lin, Wenbin
Favorite
  |  
  
Submit date:2023/05/25
Cell proliferation
Lipid bilayers
Molecular dynamics
Photosensitizers
Self assembly
Tumors
Amphiphilics
Breast tumour
Co-localization studies
Dynamics simulation
Light irradiations
Live-cell imaging
Lysosomal membranes
Membrane permeabilization
Photosensitiser
Sub-cellular
Potent Antimicrobial and Antibiofilm Activities of Feleucin-K3 Analogs Modified by alpha-(4-Pentenyl)-Ala against Multidrug-Resistant Bacteria
期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 5
Authors:
Guo, Xiaomin
;
Yan, Tiantian
;
Rao, Jing
;
Yue, Xin
;
Pei, Xiong
;
Deng, Jiahui
;
Sun, Wangsheng
;
Yang, Wenle
;
Zhang, Bangzhi
;
Xie, JQ(谢俊秋)
...
Guo, Xiaomin
;
Yan, Tiantian
;
Rao, Jing
;
Yue, Xin
;
Pei, Xiong
;
Deng, Jiahui
;
Sun, Wangsheng
;
Yang, Wenle
;
Zhang, Bangzhi
;
Xie, JQ(谢俊秋)
Adobe PDF(5637Kb)
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Submit date:2021/06/17
antimicrobial peptide analogsunnatural hydrophobic amino acidalpha-(4-pentenyl)-Alaantimicrobial activityantibiofilm activity
Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 158
Authors:
Zhu, Ningyi
;
Zhong, Chao
;
Liu, Tianqi
;
Zhu, Yuewen
;
Gou, Sanhu
;
Bao, Hexin
;
Yao, Jia
;
Ni, Jingman
Favorite
  |  
  
Submit date:2021/04/16
Antimicrobial peptides
Cell selectivity
Antibiotic adjuvant
Rifampin
Rifampin-resistant Escherichia coli
Gram-negative bacteria
Multiple action mechanism and in vivo antimicrobial efficacy of antimicrobial peptide Jelleine-I
期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2021, 卷号: 27, 期号: 3
Authors:
Jia, Fengjing
;
Wang, Jiayi
;
Zhang, Lishi
;
Zhou, Jingjing
;
He, Yuhang
;
Lu, Yaqi
;
Liu, Kexin
;
Yan, Wenjin
;
Wang, Kairong
Adobe PDF(13051Kb)
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Submit date:2021/04/16
action mode
antimicrobial agent
antimicrobial peptide
Jelleine‐
I
Hepatoprotective effect of crude polysaccharide isolated from Lycium barbarum L. against alcohol-induced oxidative damage involves Nrf2 signaling
期刊论文
Food Science & Nutrition, 2020, 卷号: 8, 期号: 12, 页码: 6528-6538
Authors:
Wang, Han
;
Li, Yongsheng
;
Liu, Jianfei
;
Di, Duolong
;
Liu, Yewei
;
Wei, Jianteng
Adobe PDF(1642Kb)
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Submit date:2020/12/18
alcohol
apoptosis
Lycium barbarum L.
oxidative damage
polysaccharide
Synthesis and anti-pseudomonal activity of new beta-Ala modified analogues of the antimicrobial peptide anoplin
期刊论文
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2020, 卷号: 310, 期号: 5
Authors:
Zhong, Chao
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Liu, Tianqi
;
Gou, Sanhu
;
Zhang, Fangyan
;
Yao, JIa
;
Xie, Junqiu
;
Ni, Jingman
Favorite
  |  
  
Submit date:2020/12/20
beta-Ala
Antimicrobial peptides
Pseudomonas aeruginosa
Multidrug-resistant strains
Biological activitiy
Study on the effects of different dimerization positions on biological activity of partial D-Amino acid substitution analogues of Anoplin
期刊论文
MICROBIAL PATHOGENESIS, 2020, 卷号: 139
Authors:
Zhong, Chao
;
Gou, Sanhu
;
Liu, Tianqi
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Liu, Hui
;
Zhang, Yun
;
Xie, Junqiu
;
Guo, Xiaomin
;
Ni, Jingman
...
Zhong, Chao
;
Gou, Sanhu
;
Liu, Tianqi
;
Zhu, Yuewen
;
Zhu, Ningyi
;
Liu, Hui
;
Zhang, Yun
;
Xie, Junqiu
;
Guo, Xiaomin
;
Ni, Jingman
Adobe PDF(9995Kb)
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Submit date:2020/08/27
Multidrug-resistant bacteria
Anoplin
Dimer antimicrobial peptides
Different dimerization positions
Biological activity
An acute lytic cell death induced by xanthohumol obstructed ROS detecting in HL-60 cells
期刊论文
TOXICOLOGY IN VITRO, 2020, 卷号: 62
Authors:
Wang, Chun-Ming
;
Huo, Xiang
;
Chen, Jun
;
Liu, Jia-Wei
;
Yang, Ting-Yu
;
Mi, Xiang-Quan
;
Meng, Yue
;
Zhou, Li
;
Lin, Chang-Jun
;
Liu, Jing
...
Wang, Chun-Ming
;
Huo, Xiang
;
Chen, Jun
;
Liu, Jia-Wei
;
Yang, Ting-Yu
;
Mi, Xiang-Quan
;
Meng, Yue
;
Zhou, Li
;
Lin, Chang-Jun
;
Liu, Jing
Adobe PDF(2157Kb)
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Submit date:2020/08/06
Xanthohumol
Reactive oxygen species
Pro-oxidant
Acute lytic cell death
Cell rupture
Symmetry breaking in hydrodynamic forces drives meiotic spindle rotation in mammalian oocytes
期刊论文
Science Advances, 2020, 卷号: 6, 期号: 14
Authors:
Wang, HaiYang
;
Li, Yizeng
;
Yang, Jing
;
Duan, Xing
;
Kalab, Petr
;
Sun, Sean X.
;
Li, Rong
Adobe PDF(3292Kb)
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Submit date:2020/08/04
Antimicrobial peptides conjugated with fatty acids on the side chain of D-amino acid promises antimicrobial potency against multidrug-resistant bacteria
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 卷号: 141
Authors:
Zhong, Chao
;
Zhu, Ningyi
;
Zhu, Yuewen
;
Liu, Tianqi
;
Gou, Sanhu
;
Xie, Junqiu
;
Yao, Jia
;
Ni, Jingman
Favorite
  |  
  
Submit date:2020/08/27
Antimicrobial peptides
Anoplin
Fatty acids conjugation
Side chain
D-amino acid
Hydrophobicity
Antimicrobial activity